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B2HK64 (B2HK64_MYCMM) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetyl-coenzyme A synthetase HAMAP MF_01123
EC=6.2.1.1 HAMAP MF_01123
Alternative name(s):
Acetate--CoA ligase HAMAP MF_01123
Acyl-activating enzyme HAMAP MF_01123
Gene names
Name:acs EMBL ACC43561.1
Synonyms:acsA HAMAP MF_01123
Ordered Locus Names:MMAR_5155
OrganismMycobacterium marinum (strain ATCC BAA-535 / M) [Complete proteome] [HAMAP]
Taxonomic identifier216594 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length651 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA. HAMAP MF_01123

Post-translational modification

Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme By similarity. HAMAP MF_01123

Sequence similarities

Belongs to the ATP-dependent AMP-binding enzyme family. HAMAP MF_01123

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site5241 By similarity HAMAP MF_01123

Amino acid modifications

Modified residue6161N6-acetyllysine By similarity HAMAP MF_01123

Sequences

Sequence LengthMass (Da)Tools
B2HK64 [UniParc].

Last modified June 10, 2008. Version 1.
Checksum: F2995BEB84CA9B19

FASTA65171,279
        10         20         30         40         50         60 
MTATSAEEPS SYPPPAEFIE QANARAELYR EAEEDRLAFW AKQADRLSWA TPFGEVLDWS 

        70         80         90        100        110        120 
DAPFAKWFVG GKLNVAYNCV DRHVEAGNGD RVAIHWVGEP IEDSRTLTYA DLQAEVSKAA 

       130        140        150        160        170        180 
NALTGLGLVA GDRVAIYLPL IPEAVIAMLA CARLGIMHSV VFGGFTANAL HARIVDAQAK 

       190        200        210        220        230        240 
LLITSDGQFR RGHPAPLKDA ADEAVSQPDS PVEHVLVVRR TGIDVSWNDE RDLWWHDVVD 

       250        260        270        280        290        300 
SASPEHTPEP FDAEQPLFLL YTSGTTGKPK GIVHTSGGYL TQCCYTVHTI FDVKPETDVF 

       310        320        330        340        350        360 
WCTADIGWVT GHTYGVYGPL ANGITEVLYE GTPNTPDEHR HFQIIEKYGV TIYYTAPTLI 

       370        380        390        400        410        420 
RTFMKWGRAI PDAHDLSSLR LLGSVGEPIN PEAWRWYRDV VGAGHTPIVD TWWQTETGSA 

       430        440        450        460        470        480 
MISPLPGIAA AKPGSAMTPL PGISAKVVDD HGDPLAPETD EGTHVTGYLV LDQPWPSMLR 

       490        500        510        520        530        540 
GIWGDPARFH YAYWSKFEDK GYYFAGDGAR LDSDGAIWVL GRIDDVMNVS GHRISTAEVE 

       550        560        570        580        590        600 
SALVGHPGVA EAAVVGVVDD TTTQAICAFV VLRGNYEQHD GTSDELRAEV AEAISPIARP 

       610        620        630        640        650 
REVHVVPELP KTRSGKIMRR LLRDIAEKRE LGDTSTLLDP TVFDAIRNAA K

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000854 Genomic DNA. Translation: ACC43561.1.
RefSeqYP_001853416.1. NC_010612.1.

3D structure databases

ProteinModelPortalB2HK64.
ModBaseSearch...

Protein-protein interaction databases

STRINGB2HK64.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBMYCT00000034086; EBMYCP00000032526; EBMYCG00000034081.
GeneID6229449.
GenomeReviewsGene locus MMAR_5155 in contig CP000854_GR.
KEGGmmi:MMAR_5155.
PATRIC18071731. VBIMycMar75906_5521.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000015141.
HOGENOMHBG547964.
OMAVISVSGH.
ProtClustDBPRK00174.

Family and domain databases

HAMAPMF_01123. Ac_CoA_synth.
[Tree]
InterProIPR011904. Ac_CoA_lig.
IPR024597. Acyl-CoA_synth_DUF3448.
IPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
[Graphical view]
KOK01895.
PANTHERPTHR24095:SF42. PTHR24095:SF42. 1 hit.
PfamPF00501. AMP-binding. 1 hit.
PF11930. DUF3448. 1 hit.
[Graphical view]
TIGRFAMsTIGR02188. Ac_CoA_lig_AcsA. 1 hit.
PROSITEPS00455. AMP_BINDING. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB2HK64_MYCMM
AccessionPrimary (citable) accession number: B2HK64
Entry history
Integrated into UniProtKB/TrEMBL: June 10, 2008
Last sequence update: June 10, 2008
Last modified: December 14, 2011
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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