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B2HJL5 (B2HJL5_MYCMM) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
tRNA (guanine-N(1)-)-methyltransferase HAMAP MF_00605
EC=2.1.1.228 HAMAP MF_00605
Alternative name(s):
M1G-methyltransferase HAMAP MF_00605
tRNA [GM37] methyltransferase HAMAP MF_00605
Gene names
Name:trmD HAMAP MF_00605 EMBL ACC40251.1
Ordered Locus Names:MMAR_1802
OrganismMycobacterium marinum (strain ATCC BAA-535 / M) [Complete proteome] [HAMAP]
Taxonomic identifier216594 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length230 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Specifically methylates guanosine-37 in various tRNAs By similarity. HAMAP MF_00605 RuleBase RU003464

Catalytic activity

S-adenosyl-L-methionine + guanine(37) in tRNA = S-adenosyl-L-homocysteine + N(1)-methylguanine(37) in tRNA. HAMAP MF_00605

S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N(1)-methylguanine. RuleBase RU003464

Subunit structure

Homodimer By similarity. HAMAP MF_00605 RuleBase RU003464

Subcellular location

Cytoplasm By similarity HAMAP MF_00605 RuleBase RU003464.

Sequence similarities

Belongs to the RNA methyltransferase TrmD family. HAMAP MF_00605 RuleBase RU003464

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region133 – 1386S-adenosyl-L-methionine binding By similarity HAMAP MF_00605

Sites

Binding site1091S-adenosyl-L-methionine; via amide nitrogen By similarity HAMAP MF_00605

Sequences

Sequence LengthMass (Da)Tools
B2HJL5 [UniParc].

Last modified June 10, 2008. Version 1.
Checksum: FC55445B5CB2D99F

FASTA23025,488
        10         20         30         40         50         60 
MKIDVVTIFP AYLDPLRQSL PGRAIASGLV DLQVHDLRRW TYDVHHSVDD SPYGGGPGMV 

        70         80         90        100        110        120 
MKAPVWGEAL DEICSAETLL VVPTPAGSLF DQATARRWSA EQHLVFACGR YEGIDQRVAE 

       130        140        150        160        170        180 
DSARRMRVEE VSIGDYVLPG GESAAVVMIE AVLRLLTGVL GNPASHQEDS FSPELDRLLE 

       190        200        210        220        230 
GPSYTRPPSW RGLDVPEILL SGDHARIATW RREVSLRRTR ERRPDLAPPE

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000854 Genomic DNA. Translation: ACC40251.1.
RefSeqYP_001850106.1. NC_010612.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB2HJL5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBMYCT00000031986; EBMYCP00000030426; EBMYCG00000031981.
GeneID6226061.
GenomeReviewsGene locus MMAR_1802 in contig CP000854_GR.
KEGGmmi:MMAR_1802.
PATRIC18064481. VBIMycMar75906_1925.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000016420.
HOGENOMHBG285805.
OMAVCGRFEG.
ProtClustDBPRK00026.

Family and domain databases

HAMAPMF_00605. TrmD.
[Tree]
InterProIPR016009. tRNA_m1G_MeTrfase.
IPR002649. tRNA_m1G_MeTrfase_bac.
IPR023148. tRNA_m1G_MeTrfase_C.
[Graphical view]
Gene3DG3DSA:1.10.1270.20. tRNA_m1G_MeTrfase_C. 1 hit.
KOK00554.
PANTHERPTHR10056. PTHR10056. 1 hit.
PfamPF01746. tRNA_m1G_MT. 1 hit.
[Graphical view]
PIRSFPIRSF000386. tRNA_mtase. 1 hit.
TIGRFAMsTIGR00088. TrmD. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB2HJL5_MYCMM
AccessionPrimary (citable) accession number: B2HJL5
Entry history
Integrated into UniProtKB/TrEMBL: June 10, 2008
Last sequence update: June 10, 2008
Last modified: December 14, 2011
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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