B2HJJ5 (B2HJJ5_MYCMM) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Ribonuclease III Rnc EMBL ACC40231.1

Gene names

Name:	rnc EMBL ACC40231.1
Ordered Locus Names:	MMAR_1782

Organism

Mycobacterium marinum (strain ATCC BAA-535 / M) [Complete proteome] [HAMAP]

Taxonomic identifier

216594 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	241 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs By similarity. SAAS SAAS011907
Catalytic activity	Endonucleolytic cleavage to 5'-phosphomonoester. SAAS SAAS011907
Subcellular location	Cytoplasm By similarity SAAS SAAS011907.
Sequence similarities	Contains 1 DRBM (double-stranded RNA-binding) domain. SAAS SAAS011907 Contains 1 RNase III domain. SAAS SAAS011907

Ontologies

Keywords
Cellular component	Cytoplasm SAAS SAAS011907
Ligand	RNA-binding SAAS SAAS011907
Molecular function	Endonuclease SAAS SAAS011907 Hydrolase Nuclease
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	RNA processing Inferred from electronic annotation. Source: InterPro rRNA catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	double-stranded RNA binding Inferred from electronic annotation. Source: InterPro ribonuclease III activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B2HJJ5 [UniParc]. Last modified June 10, 2008. Version 1. Checksum: 0E55F2B0412195B7	FASTA	241	25,390
	10 20 30 40 50 60 MSRQALLDAV GVELPEELVT LALTHRSYAY ENGGLPTNER LEFLGDAVLG LTITDELFHR 70 80 90 100 110 120 HPERSEGDLA KLRASVVNTQ ALADVARHLS EHGLGAHMLL GRGEANTGGA DKSSILADGM 130 140 150 160 170 180 ESLLGAIYLH HGMEVAREAI LRIFGPLLDA APTLGAGLDW KTSLQELTAS RSLGAPSYAV 190 200 210 220 230 240 TSTGPDHHKE FTAVVVVNNT EYGSGVGRSK KEAEQKAAAA AYQALEGLEV LDGAMPGNSS A

References

[1]

"Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis." Stinear T.P., Seemann T., Harrison P.F., Jenkin G.A., Davies J.K., Johnson P.D., Abdellah Z., Arrowsmith C., Chillingworth T., Churcher C., Clarke K., Cronin A., Davis P., Goodhead I., Holroyd N., Jagels K., Lord A., Moule S. , Mungall K., Norbertczak H., Quail M.A., Rabbinowitsch E., Walker D., White B., Whitehead S., Small P.L., Brosch R., Ramakrishnan L., Fischbach M.A., Parkhill J., Cole S.T. Genome Res. 18:729-741(2008) [PubMed: 18403782] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000854 Genomic DNA. Translation: ACC40231.1.
RefSeq	YP_001850086.1. NC_010612.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B2HJJ5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000030876; EBMYCP00000029316; EBMYCG00000030871.
GeneID	6226041.
GenomeReviews	Gene locus MMAR_1782 in contig CP000854_GR.
KEGG	mmi:MMAR_1782.
PATRIC	18064439. VBIMycMar75906_1904.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000017732.
HOGENOM	HBG744556.
OMA	ALTHKSF.
ProtClustDB	PRK00102.
Family and domain databases
HAMAP	MF_00104. RNase_III. [Tree]
InterPro	IPR001159. Ds-RNA-bd. IPR014720. dsRNA-bd-like. IPR000999. RNase_III. IPR011907. RNase_III_bac. [Graphical view]
Gene3D	G3DSA:3.30.160.20. dsRNA-bd-like. 1 hit. G3DSA:1.10.1520.10. RNase_III. 1 hit.
KO	K03685.
PANTHER	PTHR11207. PTHR11207. 1 hit.
Pfam	PF00035. dsrm. 1 hit. PF00636. Ribonuclease_3. 1 hit. [Graphical view]
SMART	SM00358. DSRM. 1 hit. SM00535. RIBOc. 1 hit. [Graphical view]
SUPFAM	SSF69065. RNase_III. 1 hit.
TIGRFAMs	TIGR02191. RNaseIII. 1 hit.
PROSITE	PS50137. DS_RBD. 1 hit. PS00517. RNASE_3_1. 1 hit. PS50142. RNASE_3_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B2HJJ5_MYCMM

Accession

Primary (citable) accession number: B2HJJ5

Entry history

Integrated into UniProtKB/TrEMBL:	June 10, 2008
Last sequence update:	June 10, 2008
Last modified:	December 14, 2011
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)