Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

B2HGL4

- GLSA_MYCMM

UniProt

B2HGL4 - GLSA_MYCMM

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Glutaminase

Gene

glsA

Organism
Mycobacterium marinum (strain ATCC BAA-535 / M)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei70 – 701SubstrateUniRule annotation
Binding sitei121 – 1211SubstrateUniRule annotation
Binding sitei165 – 1651SubstrateUniRule annotation
Binding sitei172 – 1721SubstrateUniRule annotation
Binding sitei196 – 1961SubstrateUniRule annotation
Binding sitei248 – 2481SubstrateUniRule annotation
Binding sitei266 – 2661Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. glutaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glutamine metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciMMAR216594:GJOB-1556-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
GlutaminaseUniRule annotation (EC:3.5.1.2UniRule annotation)
Gene namesi
Name:glsAUniRule annotation
Ordered Locus Names:MMAR_1548
OrganismiMycobacterium marinum (strain ATCC BAA-535 / M)
Taxonomic identifieri216594 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
ProteomesiUP000001190: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 320320GlutaminasePRO_1000115699Add
BLAST

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi216594.MMAR_1548.

Structurei

3D structure databases

ProteinModelPortaliB2HGL4.
SMRiB2HGL4. Positions 10-312.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2066.
HOGENOMiHOG000216890.
KOiK01425.
OMAiQCSVGVT.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

B2HGL4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAPTSVSNAR IEKAVLDAHE KQKNKHGGKN ADYIPILAQV PSTLFGVSVA
60 70 80 90 100
TVDGQVFTAG DAGYEFALES ISKIFTLALV IEQRGPRELR LKVGADPTGE
110 120 130 140 150
AFNSVLALEL HNDKPMSPLV NAGAISTTSL VDAVGPEDRW RQIVGAQSDF
160 170 180 190 200
AGRQISISEE INASEQATNF HNRAIAWLLR GSGYIYCDPM EACDIYTRQC
210 220 230 240 250
STLVTTADLA VMGATLANGG TNPITGKRVI ARKNVPHVLA EMTMEGVYTR
260 270 280 290 300
SGDWAYTVGL PAKSGVGGGL VAVAPGQLAI AAFSPPLDKV GNSVRAQAAV
310 320
AQIADTLQLG LFNVPGEEDE
Length:320
Mass (Da):33,748
Last modified:June 10, 2008 - v1
Checksum:i538A7317BF2254ED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000854 Genomic DNA. Translation: ACC40000.1.
RefSeqiYP_001849855.1. NC_010612.1.

Genome annotation databases

EnsemblBacteriaiACC40000; ACC40000; MMAR_1548.
GeneIDi6225805.
KEGGimmi:MMAR_1548.
PATRICi18063921. VBIMycMar75906_1648.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000854 Genomic DNA. Translation: ACC40000.1 .
RefSeqi YP_001849855.1. NC_010612.1.

3D structure databases

ProteinModelPortali B2HGL4.
SMRi B2HGL4. Positions 10-312.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 216594.MMAR_1548.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACC40000 ; ACC40000 ; MMAR_1548 .
GeneIDi 6225805.
KEGGi mmi:MMAR_1548.
PATRICi 18063921. VBIMycMar75906_1648.

Phylogenomic databases

eggNOGi COG2066.
HOGENOMi HOG000216890.
KOi K01425.
OMAi QCSVGVT.
OrthoDBi EOG6N94BK.

Enzyme and pathway databases

BioCyci MMAR216594:GJOB-1556-MONOMER.

Family and domain databases

Gene3Di 3.40.710.10. 1 hit.
HAMAPi MF_00313. Glutaminase.
InterProi IPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view ]
PANTHERi PTHR12544. PTHR12544. 1 hit.
Pfami PF04960. Glutaminase. 1 hit.
[Graphical view ]
SUPFAMi SSF56601. SSF56601. 1 hit.
TIGRFAMsi TIGR03814. Gln_ase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-535 / M.

Entry informationi

Entry nameiGLSA_MYCMM
AccessioniPrimary (citable) accession number: B2HGL4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: June 10, 2008
Last modified: October 1, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3