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Protein

Glutaminase

Gene

glsA

Organism
Mycobacterium marinum (strain ATCC BAA-535 / M)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei70SubstrateUniRule annotation1
Binding sitei121SubstrateUniRule annotation1
Binding sitei165SubstrateUniRule annotation1
Binding sitei172SubstrateUniRule annotation1
Binding sitei196SubstrateUniRule annotation1
Binding sitei248SubstrateUniRule annotation1
Binding sitei266Substrate; via amide nitrogenUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
GlutaminaseUniRule annotation (EC:3.5.1.2UniRule annotation)
Gene namesi
Name:glsAUniRule annotation
Ordered Locus Names:MMAR_1548
OrganismiMycobacterium marinum (strain ATCC BAA-535 / M)
Taxonomic identifieri216594 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacterium
Proteomesi
  • UP000001190 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001156991 – 320GlutaminaseAdd BLAST320

Proteomic databases

PRIDEiB2HGL4

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi216594.MMAR_1548

Structurei

3D structure databases

ProteinModelPortaliB2HGL4
SMRiB2HGL4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CSV Bacteria
COG2066 LUCA
HOGENOMiHOG000216890
KOiK01425
OMAiMYTCGMY
OrthoDBiPOG091H02PU

Family and domain databases

HAMAPiMF_00313 Glutaminase, 1 hit
InterProiView protein in InterPro
IPR012338 Beta-lactam/transpept-like
IPR015868 Glutaminase
PANTHERiPTHR12544 PTHR12544, 1 hit
PfamiView protein in Pfam
PF04960 Glutaminase, 1 hit
SUPFAMiSSF56601 SSF56601, 1 hit
TIGRFAMsiTIGR03814 Gln_ase, 1 hit

Sequencei

Sequence statusi: Complete.

B2HGL4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPTSVSNAR IEKAVLDAHE KQKNKHGGKN ADYIPILAQV PSTLFGVSVA
60 70 80 90 100
TVDGQVFTAG DAGYEFALES ISKIFTLALV IEQRGPRELR LKVGADPTGE
110 120 130 140 150
AFNSVLALEL HNDKPMSPLV NAGAISTTSL VDAVGPEDRW RQIVGAQSDF
160 170 180 190 200
AGRQISISEE INASEQATNF HNRAIAWLLR GSGYIYCDPM EACDIYTRQC
210 220 230 240 250
STLVTTADLA VMGATLANGG TNPITGKRVI ARKNVPHVLA EMTMEGVYTR
260 270 280 290 300
SGDWAYTVGL PAKSGVGGGL VAVAPGQLAI AAFSPPLDKV GNSVRAQAAV
310 320
AQIADTLQLG LFNVPGEEDE
Length:320
Mass (Da):33,748
Last modified:June 10, 2008 - v1
Checksum:i538A7317BF2254ED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000854 Genomic DNA Translation: ACC40000.1
RefSeqiWP_011741248.1, NC_010612.1

Genome annotation databases

EnsemblBacteriaiACC40000; ACC40000; MMAR_1548
GeneIDi34340252
KEGGimmi:MMAR_1548

Similar proteinsi

Entry informationi

Entry nameiGLSA_MYCMM
AccessioniPrimary (citable) accession number: B2HGL4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: June 10, 2008
Last modified: May 23, 2018
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health