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B2HGE8 (B2HGE8_MYCMM) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
NADH-quinone oxidoreductase subunit A HAMAP-Rule MF_01394
EC=1.6.99.5 HAMAP-Rule MF_01394
Alternative name(s):
NADH dehydrogenase I subunit A HAMAP-Rule MF_01394
NDH-1 subunit A HAMAP-Rule MF_01394
NUO1 HAMAP-Rule MF_01394
Gene names
Name:nuoA HAMAP-Rule MF_01394 EMBL ACC39934.1
Ordered Locus Names:MMAR_1483 EMBL ACC39934.1
OrganismMycobacterium marinum (strain ATCC BAA-535 / M) [Complete proteome] [HAMAP] EMBL ACC39934.1
Taxonomic identifier216594 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium ›

Protein attributes

Sequence length162 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain By similarity. RuleBase RU003639

NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient By similarity. HAMAP-Rule MF_01394

Catalytic activity

NADH + quinone = NAD+ + quinol. HAMAP-Rule MF_01394 RuleBase RU003639

Subunit structure

NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex By similarity. HAMAP-Rule MF_01394

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01394.

Membrane; Multi-pass membrane protein By similarity RuleBase RU003639.

Sequence similarities

Belongs to the complex I subunit 3 family. HAMAP-Rule MF_01394 RuleBase RU003639

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Transmembrane40 – 6021Helical; By similarity HAMAP-Rule MF_01394
Transmembrane106 – 12621Helical; By similarity HAMAP-Rule MF_01394
Transmembrane134 – 15421Helical; By similarity HAMAP-Rule MF_01394

Sequences

Sequence LengthMass (Da)Tools
B2HGE8 [UniParc].

Last modified June 10, 2008. Version 1.
Checksum: A79130DEC9FFD07A

FASTA16217,604
        10         20         30         40         50         60 
MLKVTVTVHT PGPSQQPSQP PGRRAGGPYD GSWSDLNAYI PILVLATLAA GFAVVSVVIA 

        70         80         90        100        110        120 
SLVGPTRFNR SKLAAYECGI EPTEAQAGAS GRETASGQRF PVKYYLTAML FIVFDIEIVF 

       130        140        150        160 
LYPWAVSFDA LGTFALVEMA IFMLTVFVAY AYVWRRGGLT WD

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000854 Genomic DNA. Translation: ACC39934.1.
RefSeqYP_001849789.1. NC_010612.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRING216594.MMAR_1483.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACC39934; ACC39934; MMAR_1483.
GeneID6225738.
KEGGmmi:MMAR_1483.
PATRIC18063787. VBIMycMar75906_1581.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0838.
HOGENOMHOG000100120.
KOK00330.
OMAIGMFGFW.
ProtClustDBPRK07928.

Enzyme and pathway databases

BioCycMMAR216594:GJOB-1489-MONOMER.

Family and domain databases

HAMAPMF_01394. NDH1_NuoA.
InterProIPR023043. NAD(P)H_OxRDtase_bac/plastid.
IPR000440. NADH_UbQ/plastoQ_OxRdtase_su3.
[Graphical view]
PANTHERPTHR11058. PTHR11058. 1 hit.
PfamPF00507. Oxidored_q4. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB2HGE8_MYCMM
AccessionPrimary (citable) accession number: B2HGE8
Entry history
Integrated into UniProtKB/TrEMBL: June 10, 2008
Last sequence update: June 10, 2008
Last modified: May 1, 2013
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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