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B2HG68 (B2HG68_MYCMM) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
2,3-dihydroxyphenylpropionate/2,3-dihydroxicinnamic acid 1,2-dioxygenase HAMAP MF_01653
EC=1.13.11.16 HAMAP MF_01653
Gene names
Name:mhpB HAMAP MF_01653 EMBL ACC43180.1
Ordered Locus Names:MMAR_4776
OrganismMycobacterium marinum (strain ATCC BAA-535 / M) [Complete proteome] [HAMAP]
Taxonomic identifier216594 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length306 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6-ketononatrienedioate, respectively By similarity. HAMAP MF_01653

Catalytic activity

(2E)-3-(2,3-dihydroxyphenyl)prop-2-enoate + O2 = 2-hydroxy-6-oxonona-2,4,7-triene-1,9-dioate. HAMAP MF_01653

3-(2,3-dihydroxyphenyl)propanoate + O2 = 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate. HAMAP MF_01653

Cofactor

Fe2+ ion By similarity. HAMAP MF_01653

Pathway

Aromatic compound metabolism; 3-phenylpropanoate degradation. HAMAP MF_01653

Subunit structure

Homotetramer By similarity. HAMAP MF_01653

Sequence similarities

Belongs to the ligB/mhpB extradiol dioxygenase family. HAMAP MF_01653

Sequences

Sequence LengthMass (Da)Tools
B2HG68 [UniParc].

Last modified June 10, 2008. Version 1.
Checksum: EB2B31B0D571399D

FASTA30632,757
        10         20         30         40         50         60 
MSHSPLLNLP GPRLDLLDEV HAAIAEAAEF VRAYDPDLVV IFSPDHYNGF FYRAMPPFCI 

        70         80         90        100        110        120 
GMYASAVGDY GTHIGALDVP TDLAADCAKA VLGADVDVAV SASMDVDHGT VQPLEKLFGT 

       130        140        150        160        170        180 
ATARPVIPIF INAIAAPLGP LRRCRALGTA VGTFLSTLDM RVLVIGSGGL SHSPPVPTLH 

       190        200        210        220        230        240 
SADPQVRERI VHGQPLTPAQ RQARQTVVME AAKSFAAGNS DLQPLNPAWD QRFLEIIDNG 

       250        260        270        280        290        300 
HLSDLDRWSN SFVTHEGGSS AHEIRTWISA FAAMAVAGPY QTKVRYYKQA ADLIAGFAIR 


TAVPIP

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000854 Genomic DNA. Translation: ACC43180.1.
RefSeqYP_001853035.1. NC_010612.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB2HG68.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBMYCT00000031641; EBMYCP00000030081; EBMYCG00000031636.
GeneID6229061.
GenomeReviewsGene locus MMAR_4776 in contig CP000854_GR.
KEGGmmi:MMAR_4776.
PATRIC18070933. VBIMycMar75906_5128.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000017557.
HOGENOMHBG565586.
OMAAHEIRTW.
ProtClustDBPRK13370.

Family and domain databases

HAMAPMF_01653. MhpB.
[Tree]
InterProIPR023789. DHPP/DHXA_dioxygenase.
IPR004183. Xdiol_dOase_suB.
[Graphical view]
Gene3DG3DSA:3.40.830.10. Xdiol_dOase_3B. 2 hits.
KOK05713.
PfamPF02900. LigB. 1 hit.
[Graphical view]
SUPFAMSSF53213. Xdiol_dOase_3B. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB2HG68_MYCMM
AccessionPrimary (citable) accession number: B2HG68
Entry history
Integrated into UniProtKB/TrEMBL: June 10, 2008
Last sequence update: June 10, 2008
Last modified: January 25, 2012
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info