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B2HEL2 (B2HEL2_MYCMM) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
N5-carboxyaminoimidazole ribonucleotide mutase PIRNR PIRNR001338
Short name=N5-CAIR mutase PIRNR PIRNR001338
EC=5.4.99.18 PIRNR PIRNR001338
Gene names
Name:purE EMBL ACC39719.1
Ordered Locus Names:MMAR_1261
OrganismMycobacterium marinum (strain ATCC BAA-535 / M) [Complete proteome] [HAMAP]
Taxonomic identifier216594 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length171 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) By similarity. PIRNR PIRNR001338

Catalytic activity

5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate. PIRNR PIRNR001338

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 2/2. PIRNR PIRNR001338

Sequence similarities

Belongs to the AIR carboxylase family. PIRNR PIRNR001338

Sequences

Sequence LengthMass (Da)Tools
B2HEL2 [UniParc].

Last modified June 10, 2008. Version 1.
Checksum: C2CA144E5DFA8D0C

FASTA17117,620
        10         20         30         40         50         60 
MAEQPRVAVI MGSDSDWSVM ADAAKALAEF DIAMEVRVVS AHRTPQVMFD YARDAAGRGI 

        70         80         90        100        110        120 
EVIIAGAGGA AHLPGMVASA TPLPVIGVPV PLARLDGLDS LLSIVQMPAG VPVATVSIGG 

       130        140        150        160        170 
ARNAGLLAVR MLGSSDPALR ARIAAFQDQL AQTVQAKDAE LQKLAGKLTR D

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000854 Genomic DNA. Translation: ACC39719.1.
RefSeqYP_001849574.1. NC_010612.1.

3D structure databases

ProteinModelPortalB2HEL2.
SMRB2HEL2. Positions 7-134.
ModBaseSearch...

Protein-protein interaction databases

STRINGB2HEL2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBMYCT00000031993; EBMYCP00000030433; EBMYCG00000031988.
GeneID6225516.
GenomeReviewsGene locus MMAR_1261 in contig CP000854_GR.
KEGGmmi:MMAR_1261.
PATRIC18063311. VBIMycMar75906_1344.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000016911.
HOGENOMHBG301965.
OMALIMGSDS.
ProtClustDBCLSK792398.

Family and domain databases

InterProIPR024694. N5-CAIR_mutase_PurE.
IPR000031. N5-CAIR_Mutase_PurE_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.7700. AIR_carboxyl. 1 hit.
KOK01588.
PfamPF00731. AIRC. 1 hit.
[Graphical view]
PIRSFPIRSF001338. AIR_carboxylase. 1 hit.
SMARTSM01001. AIRC. 1 hit.
[Graphical view]
SUPFAMSSF52255. AIR_carboxyl. 1 hit.
TIGRFAMsTIGR01162. PurE. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB2HEL2_MYCMM
AccessionPrimary (citable) accession number: B2HEL2
Entry history
Integrated into UniProtKB/TrEMBL: June 10, 2008
Last sequence update: June 10, 2008
Last modified: January 25, 2012
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info