B2HEL1 (B2HEL1_MYCMM) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Phosphoribosylaminoimidazole carboxylase ATPase subunit PurK (Air carboxylase) (AirC) EMBL ACC39718.1

Gene names

Name:	purK EMBL ACC39718.1
Ordered Locus Names:	MMAR_1260

Organism

Mycobacterium marinum (strain ATCC BAA-535 / M) [Complete proteome] [HAMAP]

Taxonomic identifier

216594 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	404 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Sequence similarities

Contains 1 ATP-grasp domain. SAAS SAAS003135

Ontologies

Keywords
Biological process	Purine biosynthesis SAAS SAAS003135
Ligand	ATP-binding SAAS SAAS003135 Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	'de novo' IMP biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ligase activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: InterPro phosphoribosylaminoimidazole carboxylase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B2HEL1 [UniParc]. Last modified June 10, 2008. Version 1. Checksum: 8C8C6EB735D7BD10	FASTA	404	43,214
	10 20 30 40 50 60 MMAVPSSRTP QVAMVGGGQL ARMTHQAAIA LGQNLRVLVN SADDPAAQVT PNVVIGSHTD 70 80 90 100 110 120 LDDLRRIAAG ADVVTFDHEH VPAELLDKLV AEGVVLAPPP QALVHAQDKL VMRRRLQALD 130 140 150 160 170 180 VPVPRYLGIH QLEELGELDA FARELDAPLV VKAVRGGYDG RGVQMARDLA DARDIASGYL 190 200 210 220 230 240 AGGVPVLVEE RVQLRRELSA LVARSPFGQG AAWPVVETVQ QDGICVAVIA PAPALSAQAG 250 260 270 280 290 300 ADAQQLALRL AAELGVVGVL AVELFETTDG ALVVNELAMR PHNSGHWTMD GSRTSQFEQH 310 320 330 340 350 360 LRAVLDYPLG DTEAIAPVTV MTNVLGAAAQ PAMSLDERLH HLFARMPDAR VHLYGKDERP 370 380 390 400 GRKVGHINFL GFDPAAVAGL RERAELAAHW LSHGQWTDGW DPHG

References

[1]

"Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis." Stinear T.P., Seemann T., Harrison P.F., Jenkin G.A., Davies J.K., Johnson P.D., Abdellah Z., Arrowsmith C., Chillingworth T., Churcher C., Clarke K., Cronin A., Davis P., Goodhead I., Holroyd N., Jagels K., Lord A., Moule S. , Mungall K., Norbertczak H., Quail M.A., Rabbinowitsch E., Walker D., White B., Whitehead S., Small P.L., Brosch R., Ramakrishnan L., Fischbach M.A., Parkhill J., Cole S.T. Genome Res. 18:729-741(2008) [PubMed: 18403782] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000854 Genomic DNA. Translation: ACC39718.1.
RefSeq	YP_001849573.1. NC_010612.1.
3D structure databases
ProteinModelPortal	B2HEL1.
ModBase	Search...
Protein-protein interaction databases
STRING	B2HEL1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000035387; EBMYCP00000033827; EBMYCG00000035382.
GeneID	6225515.
GenomeReviews	Gene locus MMAR_1260 in contig CP000854_GR.
KEGG	mmi:MMAR_1260.
PATRIC	18063309. VBIMycMar75906_1343.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000015722.
HOGENOM	HBG516369.
OMA	GRKMGHF.
ProtClustDB	PRK06019.
Family and domain databases
InterPro	IPR005875. AIR_COase_ATPase-su. IPR011761. ATP-grasp. IPR003135. ATP-grasp_carboxylate-amine. IPR013815. ATP_grasp_subdomain_1. IPR013816. ATP_grasp_subdomain_2. IPR013817. Pre-ATP_grasp. IPR016185. PreATP-grasp-like. IPR011054. Rudment_hybrid_motif. [Graphical view]
Gene3D	G3DSA:3.30.1490.20. ATP_grasp_subdomain_1. 1 hit. G3DSA:3.30.470.20. ATP_grasp_subdomain_2. 1 hit. G3DSA:3.40.50.20. Pre-ATP_grasp. 1 hit.
KO	K01589.
Pfam	PF02222. ATP-grasp. 1 hit. [Graphical view]
SUPFAM	SSF52440. PreATP-grasp-like. 1 hit. SSF51246. Rudmnt_hyb_motif. 1 hit.
TIGRFAMs	TIGR01161. PurK. 1 hit.
PROSITE	PS50975. ATP_GRASP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B2HEL1_MYCMM

Accession

Primary (citable) accession number: B2HEL1

Entry history

Integrated into UniProtKB/TrEMBL:	June 10, 2008
Last sequence update:	June 10, 2008
Last modified:	December 14, 2011
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)