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Protein
Submitted name:

O-acetylhomoserine sulfhydrylase MetC

Gene

metC

Organism
Mycobacterium marinum (strain ATCC BAA-535 / M)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
O-acetylhomoserine sulfhydrylase MetCImported
Gene namesi
Name:metCImported
Ordered Locus Names:MMAR_1185Imported
OrganismiMycobacterium marinum (strain ATCC BAA-535 / M)Imported
Taxonomic identifieri216594 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacterium
Proteomesi
  • UP000001190 Componenti: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei220N6-(pyridoxal phosphate)lysineUniRule annotation1

Interactioni

Protein-protein interaction databases

STRINGi216594.MMAR_1185.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4KAMX-ray2.00A/B/C/D1-449[»]
ProteinModelPortaliB2HDS7.
SMRiB2HDS7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the trans-sulfuration enzymes family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108IQK. Bacteria.
COG2873. LUCA.
HOGENOMiHOG000246417.
KOiK01740.
OMAiEPAYHGV.
OrthoDBiPOG091H053G.

Family and domain databases

CDDicd00614. CGS_like. 1 hit.
Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR000277. Cys/Met-Metab_PyrdxlP-dep_enz.
IPR006235. OAc-hSer/O-AcSer_sulfhydrylase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11808. PTHR11808. 2 hits.
PTHR11808:SF12. PTHR11808:SF12. 2 hits.
PfamiPF01053. Cys_Met_Meta_PP. 1 hit.
[Graphical view]
PIRSFiPIRSF001434. CGS. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01326. OAH_OAS_sulfhy. 1 hit.
PROSITEiPS00868. CYS_MET_METAB_PP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B2HDS7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAENTSTDA DPTAHWSFET KQIHAGQQPD SATNARALPI YQTTSYTFEN
60 70 80 90 100
TAHAAALFGL EVPGNIYTRL GNPTTDVVEQ RIAALEGGVA ALFLSSGQAA
110 120 130 140 150
ETFAILNLAG AGDHIVSSPR LYGGTYNLFH YSLAKLGIEV SFVDDPDNLD
160 170 180 190 200
SWQAAVRPNT KAFFGETISN PQIDLLDTPG VAEVAHRNGI PLIVDNTIAT
210 220 230 240 250
PYLIRPFTQG ADIVVHSATK YLGGHGAAIA GVIVDGGTFD WTQGRFPEFT
260 270 280 290 300
TPDPSYHGVV FAELGAPAYA LKARVQLLRD LGSAASPFNA FLVAQGLETL
310 320 330 340 350
SLRIERHVSN AQRVAEFLAD REDVVTVNYA GLPGSPWHER AKKLSPKGTG
360 370 380 390 400
AVLSFELAGG VEAGKAFVNA LKLHSHVANI GDVRSLVIHP ASTTHAQLSP
410 420 430 440
AEQLSTGVSP GLVRLAVGIE GIEDILADLE LGFAAARKFS GDSQAVAAI
Length:449
Mass (Da):47,398
Last modified:June 10, 2008 - v1
Checksum:i0D4CE32AF70A6FAB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000854 Genomic DNA. Translation: ACC39643.1.
RefSeqiWP_012393065.1. NC_010612.1.

Genome annotation databases

EnsemblBacteriaiACC39643; ACC39643; MMAR_1185.
KEGGimmi:MMAR_1185.
PATRICi18063153. VBIMycMar75906_1265.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000854 Genomic DNA. Translation: ACC39643.1.
RefSeqiWP_012393065.1. NC_010612.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4KAMX-ray2.00A/B/C/D1-449[»]
ProteinModelPortaliB2HDS7.
SMRiB2HDS7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi216594.MMAR_1185.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACC39643; ACC39643; MMAR_1185.
KEGGimmi:MMAR_1185.
PATRICi18063153. VBIMycMar75906_1265.

Phylogenomic databases

eggNOGiENOG4108IQK. Bacteria.
COG2873. LUCA.
HOGENOMiHOG000246417.
KOiK01740.
OMAiEPAYHGV.
OrthoDBiPOG091H053G.

Family and domain databases

CDDicd00614. CGS_like. 1 hit.
Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR000277. Cys/Met-Metab_PyrdxlP-dep_enz.
IPR006235. OAc-hSer/O-AcSer_sulfhydrylase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11808. PTHR11808. 2 hits.
PTHR11808:SF12. PTHR11808:SF12. 2 hits.
PfamiPF01053. Cys_Met_Meta_PP. 1 hit.
[Graphical view]
PIRSFiPIRSF001434. CGS. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01326. OAH_OAS_sulfhy. 1 hit.
PROSITEiPS00868. CYS_MET_METAB_PP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB2HDS7_MYCMM
AccessioniPrimary (citable) accession number: B2HDS7
Entry historyi
Integrated into UniProtKB/TrEMBL: June 10, 2008
Last sequence update: June 10, 2008
Last modified: November 2, 2016
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.