B2HD08 (B2HD08_MYCMM) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein HAMAP MF_01445

Gene names

Name:	gcp HAMAP MF_01445 EMBL ACC39580.1
Ordered Locus Names:	MMAR_1124

Organism

Mycobacterium marinum (strain ATCC BAA-535 / M) [Complete proteome] [HAMAP]

Taxonomic identifier

216594 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	343 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm By similarity HAMAP MF_01445 SAAS SAAS017860.
Sequence similarities	Belongs to the KAE1 / YgjD family. HAMAP MF_01445

Ontologies

Keywords
Biological process	tRNA processing HAMAP MF_01445 SAAS SAAS017860
Cellular component	Cytoplasm HAMAP MF_01445 SAAS SAAS017860
Molecular function	Hydrolase Protease EMBL ACC39580.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: UniProtKB-KW threonylcarbamoyladenosine biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B2HD08 [UniParc]. Last modified June 10, 2008. Version 1. Checksum: CFBBC51CC2D86D42	FASTA	343	34,973
	10 20 30 40 50 60 MPGTVILAIE TSCDETGVGI TRLEADGTLT LLADEVASSV DEHVRFGGVV PEIASRAHLE 70 80 90 100 110 120 ALGPAMRRAL TTAGIVRPDV VATTIGPGLA GALLVGVAAA KAYAAAWGVP FYAVNHLGGH 130 140 150 160 170 180 LAADVYEHGP LPECVALLVS GGHTHLLHVR SLGEPMVELG ATVDDAAGEA YDKVARLLGL 190 200 210 220 230 240 GYPGGKVLDD LARSGDPDAI VFPRGMTGPS DDPCAFSFSG LKTAVARYVE AHPDFRPADV 250 260 270 280 290 300 AAGFQEAVAD VLTRKAVRAA TGLGVSTLLI AGGVAANSRL RELATQRCSE AGLTLRIPRP 310 320 330 340 RLCTDNGAMI AAFAAHLVAA KAAPSPLDVP SDPGLPVVKG QVG

References

[1]

"Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis." Stinear T.P., Seemann T., Harrison P.F., Jenkin G.A., Davies J.K., Johnson P.D., Abdellah Z., Arrowsmith C., Chillingworth T., Churcher C., Clarke K., Cronin A., Davis P., Goodhead I., Holroyd N., Jagels K., Lord A., Moule S. , Mungall K., Norbertczak H., Quail M.A., Rabbinowitsch E., Walker D., White B., Whitehead S., Small P.L., Brosch R., Ramakrishnan L., Fischbach M.A., Parkhill J., Cole S.T. Genome Res. 18:729-741(2008) [PubMed: 18403782] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000854 Genomic DNA. Translation: ACC39580.1.
RefSeq	YP_001849435.1. NC_010612.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B2HD08.
Protein family/group databases
MEROPS	M22.A01.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000032213; EBMYCP00000030653; EBMYCG00000032208.
GeneID	6225377.
GenomeReviews	Gene locus MMAR_1124 in contig CP000854_GR.
KEGG	mmi:MMAR_1124.
PATRIC	18063019. VBIMycMar75906_1198.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000017447.
HOGENOM	HBG304663.
OMA	PLYGVNH.
ProtClustDB	PRK09604.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017860. Peptidase_M22_CS. IPR017861. Peptidase_M22_subgr. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B2HD08_MYCMM

Accession

Primary (citable) accession number: B2HD08

Entry history

Integrated into UniProtKB/TrEMBL:	June 10, 2008
Last sequence update:	June 10, 2008
Last modified:	December 14, 2011
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)