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Protein

Phosphoglucosamine mutase

Gene

glmM

Organism
Mycobacterium marinum (strain ATCC BAA-535 / M)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.UniRule annotation

Catalytic activityi

Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate.UniRule annotation

Cofactori

Mg2+UniRule annotationNote: Binds 1 Mg2+ ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei102Phosphoserine intermediateUniRule annotation1
Metal bindingi102Magnesium; via phosphate groupUniRule annotation1
Metal bindingi240MagnesiumUniRule annotation1
Metal bindingi242MagnesiumUniRule annotation1
Metal bindingi244MagnesiumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
LigandMagnesium, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglucosamine mutaseUniRule annotation (EC:5.4.2.10UniRule annotation)
Gene namesi
Name:glmMUniRule annotation
Ordered Locus Names:MMAR_1108
OrganismiMycobacterium marinum (strain ATCC BAA-535 / M)
Taxonomic identifieri216594 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacterium
Proteomesi
  • UP000001190 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10002011201 – 445Phosphoglucosamine mutaseAdd BLAST445

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei102PhosphoserineUniRule annotation1

Post-translational modificationi

Activated by phosphorylation.UniRule annotation

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiB2HCZ2

Interactioni

Protein-protein interaction databases

STRINGi216594.MMAR_1108

Structurei

3D structure databases

SMRiB2HCZ2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the phosphohexose mutase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107QJF Bacteria
COG1109 LUCA
HOGENOMiHOG000268678
KOiK03431
OMAiMFGEEYT
OrthoDBiPOG091H02H5

Family and domain databases

CDDicd05802 GlmM, 1 hit
HAMAPiMF_01554_B GlmM_B, 1 hit
InterProiView protein in InterPro
IPR005844 A-D-PHexomutase_a/b/a-I
IPR016055 A-D-PHexomutase_a/b/a-I/II/III
IPR005845 A-D-PHexomutase_a/b/a-II
IPR005846 A-D-PHexomutase_a/b/a-III
IPR005843 A-D-PHexomutase_C
IPR036900 A-D-PHexomutase_C_sf
IPR016066 A-D-PHexomutase_CS
IPR005841 Alpha-D-phosphohexomutase_SF
IPR006352 GlmM_bact
PfamiView protein in Pfam
PF02878 PGM_PMM_I, 1 hit
PF02879 PGM_PMM_II, 1 hit
PF02880 PGM_PMM_III, 1 hit
PF00408 PGM_PMM_IV, 1 hit
PRINTSiPR00509 PGMPMM
SUPFAMiSSF53738 SSF53738, 3 hits
SSF55957 SSF55957, 1 hit
TIGRFAMsiTIGR01455 glmM, 1 hit
PROSITEiView protein in PROSITE
PS00710 PGM_PMM, 1 hit

Sequencei

Sequence statusi: Complete.

B2HCZ2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRLFGTDGV RGVANRELTA ELALALGAAT AQHLASSTGP GRRVAVVGRD
60 70 80 90 100
PRASGEMLEA AVIAGLTSQG VDALRVGVLP TPAVAYLTGA YDADFGVMIS
110 120 130 140 150
ASHNPMPDNG IKIFGPGGHK LDDATEDRIE SLVAAGPGLR PVGSEIGRVI
160 170 180 190 200
DAEDAADRYL RHVSKACTTR LDGLTVVVDC AHGAASEVGP RAYRAAGARV
210 220 230 240 250
IEINADPNGL NINDDCGSTH LEAIRAAVLA HGADLGVAHD GDADRCLAVD
260 270 280 290 300
ANGDLVDGDA IMVVLALAMQ EAGELASDTL VTTVMSNLGL HLAMREAGVN
310 320 330 340 350
VRTTGVGDRY VLEELRAGDY SLGGEQSGHI VMPGLGSTGD GIVTGLRLMT
360 370 380 390 400
RMVATGASLA ALASRMQTLP QVLINVQVTD KAAAAAAPSV QAAVDRAETE
410 420 430 440
LGDTGRILLR PSGTEPLIRV MVEAADEEAA HRLATSVADA VSAAG
Length:445
Mass (Da):45,386
Last modified:June 10, 2008 - v1
Checksum:i1CA32A663854C94B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000854 Genomic DNA Translation: ACC39564.1
RefSeqiWP_012392995.1, NC_010612.1

Genome annotation databases

EnsemblBacteriaiACC39564; ACC39564; MMAR_1108
GeneIDi34342153
KEGGimmi:MMAR_1108

Similar proteinsi

Entry informationi

Entry nameiGLMM_MYCMM
AccessioniPrimary (citable) accession number: B2HCZ2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: June 10, 2008
Last modified: May 23, 2018
This is version 60 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health