B2HCW1 (B2HCW1_MYCMM) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
3-hydroxyisobutyrate dehydrogenase, MmsB EMBL ACC39533.1

Gene names

Name:	mmsB EMBL ACC39533.1
Ordered Locus Names:	MMAR_1077

Organism

Mycobacterium marinum (strain ATCC BAA-535 / M) [Complete proteome] [HAMAP]

Taxonomic identifier

216594 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	294 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt Inferred from electronic annotation. Source: InterPro valine metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	3-hydroxyisobutyrate dehydrogenase activity Inferred from electronic annotation. Source: InterPro NAD binding Inferred from electronic annotation. Source: InterPro phosphogluconate dehydrogenase (decarboxylating) activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B2HCW1 [UniParc]. Last modified June 10, 2008. Version 1. Checksum: DA7E5694C0F4B8AB	FASTA	294	29,412
	10 20 30 40 50 60 MTKSCQIAFL GLGHMGAPMS ANLIGAGHTV RGFDPVPAAA SAAAAKGATM FDSAAEAVAG 70 80 90 100 110 120 ADVVITMLPN GAVVKRCYAE VLPAARSGAL FIDSSTISVN DAREVHALAE SHGMAQLDAP 130 140 150 160 170 180 VSGGVKGAVA GTLAFMVGGD QSALAQARPV LEPMAGKIIH CGAAGAGQAA KVCNNMVLAV 190 200 210 220 230 240 QQIAIGEAFV LAENLGLDAQ SLFDVITGAT GNCWAVHTNC PVPGPVPTSP ANNDFKPGFA 250 260 270 280 290 TALMNKDLGL AMDAVTSTGS AAPLGSHAAE IYAKFAADHA DQDFSAVIEM LRGS

References

[1]

"Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis." Stinear T.P., Seemann T., Harrison P.F., Jenkin G.A., Davies J.K., Johnson P.D., Abdellah Z., Arrowsmith C., Chillingworth T., Churcher C., Clarke K., Cronin A., Davis P., Goodhead I., Holroyd N., Jagels K., Lord A., Moule S. , Mungall K., Norbertczak H., Quail M.A., Rabbinowitsch E., Walker D., White B., Whitehead S., Small P.L., Brosch R., Ramakrishnan L., Fischbach M.A., Parkhill J., Cole S.T. Genome Res. 18:729-741(2008) [PubMed: 18403782] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000854 Genomic DNA. Translation: ACC39533.1.
RefSeq	YP_001849388.1. NC_010612.1.
3D structure databases
ProteinModelPortal	B2HCW1.
ModBase	Search...
Protein-protein interaction databases
STRING	B2HCW1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000031517; EBMYCP00000029957; EBMYCG00000031512.
GeneID	6225330.
GenomeReviews	Gene locus MMAR_1077 in contig CP000854_GR.
KEGG	mmi:MMAR_1077.
PATRIC	18062921. VBIMycMar75906_1149.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000015861.
HOGENOM	HBG729179.
OMA	PMARNLI.
ProtClustDB	CLSK790712.
Family and domain databases
InterPro	IPR002204. 3-OH-isobutyrate_DH-rel_CS. IPR015815. 3hydroxyacid_DH/Rdtase. IPR008927. 6-PGluconate_DH_C-like. IPR006115. 6PGDH_NADP-bd. IPR013328. DH_multihelical. IPR011548. IsoBut3OH_DH. IPR016040. NAD(P)-bd_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit. G3DSA:1.10.1040.10. Opine_DH. 1 hit.
KO	K00020.
PANTHER	PTHR22981. 3hydroxy_acid_DH. 1 hit.
Pfam	PF03446. NAD_binding_2. 1 hit. [Graphical view]
SUPFAM	SSF48179. 6DGDH_C_like. 1 hit.
TIGRFAMs	TIGR01692. HIBADH. 1 hit.
PROSITE	PS00895. 3_HYDROXYISOBUT_DH. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B2HCW1_MYCMM

Accession

Primary (citable) accession number: B2HCW1

Entry history

Integrated into UniProtKB/TrEMBL:	June 10, 2008
Last sequence update:	June 10, 2008
Last modified:	December 14, 2011
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)