B2HCT3 (B2HCT3_MYCMM) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
50S ribosomal protein L5 HAMAP MF_01333 RuleBase RU003931

Gene names

Name:	rplE HAMAP MF_01333 EMBL ACC39505.1
Ordered Locus Names:	MMAR_1047

Organism

Mycobacterium marinum (strain ATCC BAA-535 / M) [Complete proteome] [HAMAP]

Taxonomic identifier

216594 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Mycobacteriaceae › Mycobacterium

Protein attributes

Sequence length	190 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement By similarity. RuleBase RU003931 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs By similarity. HAMAP MF_01333
Subunit structure	Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome By similarity. HAMAP MF_01333
Sequence similarities	Belongs to the ribosomal protein L5P family. HAMAP MF_01333 RuleBase RU003930

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding HAMAP MF_01333 RuleBase RU003931 tRNA-binding HAMAP MF_01333 RuleBase RU003931
Molecular function	Ribonucleoprotein Ribosomal protein HAMAP MF_01333 RuleBase RU003930 EMBL ACC39505.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: HAMAP
Cellular component	ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	rRNA binding Inferred from electronic annotation. Source: HAMAP structural constituent of ribosome Inferred from electronic annotation. Source: InterPro tRNA binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B2HCT3 [UniParc]. Last modified June 10, 2008. Version 1. Checksum: 378F50C9C5B8CBDB	FASTA	190	21,305
	10 20 30 40 50 60 MSTTDSAVKI PPRLKERYRS EIRDVLHKQF GYGNVMQIPT VTKVVVNMGV GEAARDAKLI 70 80 90 100 110 120 NGAVSDLALI TGQRPEIRKA RKSIAQFKLR EGMPVGVRAT LRGDRMWEFL DRLTSIALPR 130 140 150 160 170 180 IRDFRGLSPK QFDGVGNYTF GLAEQSVFHE IDVDKIDRVR GMDINVVTSA TTDEEGRALL 190 RALGFPFKEN

References

[1]

"Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis." Stinear T.P., Seemann T., Harrison P.F., Jenkin G.A., Davies J.K., Johnson P.D., Abdellah Z., Arrowsmith C., Chillingworth T., Churcher C., Clarke K., Cronin A., Davis P., Goodhead I., Holroyd N., Jagels K., Lord A., Moule S. , Mungall K., Norbertczak H., Quail M.A., Rabbinowitsch E., Walker D., White B., Whitehead S., Small P.L., Brosch R., Ramakrishnan L., Fischbach M.A., Parkhill J., Cole S.T. Genome Res. 18:729-741(2008) [PubMed: 18403782] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000854 Genomic DNA. Translation: ACC39505.1.
RefSeq	YP_001849360.1. NC_010612.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B2HCT3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBMYCT00000034402; EBMYCP00000032842; EBMYCG00000034397.
GeneID	6225301.
GenomeReviews	Gene locus MMAR_1047 in contig CP000854_GR.
KEGG	mmi:MMAR_1047.
PATRIC	18062857. VBIMycMar75906_1117.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000016450.
HOGENOM	HBG592167.
OMA	RQGMPIG.
ProtClustDB	PRK00010.
Family and domain databases
HAMAP	MF_01333_B. Ribosomal_L5_B. [Tree]
InterPro	IPR002132. Ribosomal_L5. IPR020930. Ribosomal_L5_bac-type. IPR022803. Ribosomal_L5_domain. [Graphical view]
Gene3D	G3DSA:3.30.1440.10. Ribosomal_L5. 1 hit.
KO	K02931.
PANTHER	PTHR11994. Ribosomal_L5. 1 hit.
Pfam	PF00281. Ribosomal_L5. 1 hit. PF00673. Ribosomal_L5_C. 1 hit. [Graphical view]
PIRSF	PIRSF002161. Ribosomal_L5. 1 hit.
SUPFAM	SSF55282. Ribosomal_L5. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B2HCT3_MYCMM

Accession

Primary (citable) accession number: B2HCT3

Entry history

Integrated into UniProtKB/TrEMBL:	June 10, 2008
Last sequence update:	June 10, 2008
Last modified:	December 14, 2011
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)