Skip Header

Contribute Send feedback
Read comments (?) or add your own

B2H0K3 (B2H0K3_BURPS) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 19. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Bifunctional purine biosynthesis protein PurH HAMAP MF_00139
Gene names
Name:purH HAMAP MF_00139 EMBL EDU08272.1
ORF Names:BURPS1655_E0415 EMBL EDU08272.1
OrganismBurkholderia pseudomallei 1655 EMBL EDU08272.1
Taxonomic identifier331109 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group

Protein attributes

Sequence length521 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

10-formyltetrahydrofolate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide = tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide. HAMAP MF_00139 SAAS SAAS002695

IMP + H2O = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide. HAMAP MF_00139 SAAS SAAS002695

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (10-formyl THF route): step 1/1. HAMAP MF_00139 SAAS SAAS002695

Purine metabolism; IMP biosynthesis via de novo pathway; IMP from 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide: step 1/1. HAMAP MF_00139 SAAS SAAS002695

Domain

The IMP cyclohydrolase activity resides in the N-terminal region By similarity. HAMAP MF_00139

Sequence similarities

Belongs to the PurH family. HAMAP MF_00139

Sequences

Sequence LengthMass (Da)Tools
B2H0K3 [UniParc].

Last modified June 10, 2008. Version 1.
Checksum: CDDA7B76B25BB0E6

FASTA52155,458
        10         20         30         40         50         60 
MIKQALISVS DKTGIVDFAK ALSALGVKLL STGGTAKLLA DAGLPVTEVA DYTGFPEMLD 

        70         80         90        100        110        120 
GRVKTLHPKV HGGILARRDL PEHMQALEAH GIPTIDLLVV NLYPFVQTIA KDDCTLADAI 

       130        140        150        160        170        180 
ENIDIGGPTM LRSAAKNHRD VTVVVDPADY AVVLDEMKAN GNTLGYKTNF RLATKVFAHT 

       190        200        210        220        230        240 
AQYDGAITNY LTSLGDDLQH GSRSAYPATL NLAFDKVQDL RYGENPHQSA AFYRDVATPA 

       250        260        270        280        290        300 
GALANYRQLQ GKELSYNNIA DSDAAWECVK TFDAPACVII KHANPCGVAV GADAGEAYAK 

       310        320        330        340        350        360 
AFQTDPTSAF GGIIAFNREV DEAAAQAVAK QFVEVLIAPS FSDAAKQVFA AKQNVRLLEI 

       370        380        390        400        410        420 
ALGEGHNAFD LKRVGGGLLV QSLDSKNVQP RELRVVTKRH PTPKEMDDLL FAWRVAKYVK 

       430        440        450        460        470        480 
SNAIVFCGNG MTLGVGAGQM SRVDSARIAS IKAQNAGLTL AGSAVASDAF FPFRDGLDVV 

       490        500        510        520 
VAAGATCVIQ PGGSVRDDEV IAAADEHNIA MVVTGVRHFR H

« Hide

References

[1]"Annotation of Burkholderia pseudomallei 1655."
DeShazer D., Woods D.E., Nierman W.C.
Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: 1655 EMBL EDU08272.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CH899712 Genomic DNA. Translation: EDU08272.1.

3D structure databases

ProteinModelPortalB2H0K3.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

PATRIC27826125. VBIBurPse91116_1961.

Family and domain databases

HAMAPMF_00139. PurH.
[Tree]
InterProIPR024051. AICAR_Tfase_dom.
IPR002695. AICARFT_IMPCHas.
IPR016193. Cytidine_deaminase-like.
IPR011607. MGS-like_dom.
[Graphical view]
Gene3DG3DSA:3.40.140.20. G3DSA:3.40.140.20. 2 hits.
G3DSA:3.40.50.1380. MGS-like_dom. 1 hit.
PANTHERPTHR11692. AICARFT_IMPCHas. 1 hit.
PfamPF01808. AICARFT_IMPCHas. 1 hit.
PF02142. MGS. 1 hit.
[Graphical view]
PIRSFPIRSF000414. AICARFT_IMPCHas. 1 hit.
SMARTSM00798. AICARFT_IMPCHas. 1 hit.
SM00851. MGS. 1 hit.
[Graphical view]
SUPFAMSSF53927. Cytidine_deaminase-like. 1 hit.
SSF52335. MGS-like_dom. 1 hit.
TIGRFAMsTIGR00355. PurH. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB2H0K3_BURPS
AccessionPrimary (citable) accession number: B2H0K3
Entry history
Integrated into UniProtKB/TrEMBL: June 10, 2008
Last sequence update: June 10, 2008
Last modified: December 14, 2011
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info