Ubiquitin-like protein 4A
Reviewed-Annotation score: <p>Annotation score: 2 out of 5</p>
<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome.</p><p><a href='../manual/annotation_score' target='_top'>More...</a></p>Annotation score: 2 out of 5-Experimental evidence at transcript leveli
<p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.</p><p><a href='../manual/protein_existence' target='_top'>More...</a></p> Select a section on the left to see content.
<p>Provides any useful information about the protein, mostly biological knowledge.</p><p><a href='../manual/function_section' target='_top'>More...</a></p>Functioni
Component of the BAT3 complex, a multiprotein complex involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. TA membrane proteins, also named type II transmembrane proteins, contain a single C-terminal transmembrane region. The complex acts by facilitating TA proteins capture by ASNA1/TRC40: it is recruited to ribosomes synthesizing membrane proteins, interacts with the transmembrane region of newly released TA proteins, and transfers them to ASNA1/TRC40 for targeting (By similarity).
<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Biological processi
<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Biological processi
Transport<p>Provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.</p><p><a href='../manual/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi
| <p>Provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.</p><p><a href='../manual/protein_names' target='_top'>More...</a></p>Protein namesi | Recommended name: Ubiquitin-like protein 4A |
| <p>Indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.</p><p><a href='../manual/gene_name' target='_top'>More...</a></p>Gene namesi | |
| <p>Provides information on the name(s) of the organism that is the source of the protein sequence.</p><p><a href='../manual/organism-name' target='_top'>More...</a></p>Organismi | Rattus norvegicus (Rat) |
| <p>Shows the unique identifier assigned by the <span class="caps">NCBI</span> to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.</p><p><a href='../manual/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri | 10116 [NCBI] |
| <p>Contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.</p><p><a href='../manual/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineagei | cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus |
| <p>Is present for entries that are part of a <a href="/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.</p><p><a href='../manual/proteomes_manual' target='_top'>More...</a></p>Proteomesi | - UP000002494
<p>A UniProt <a href="/manual/proteomes_manual">proteome</a> can consist of several components. <br />The component name refers to the genomic component encoding a set of proteins. <br />These range from a single component such as Viral genomes to several components as in the case of eukaryotic chromosomes. They may also represent different stages in a genome project and include components such as contigs, scaffolds or Whole Genome Shotgun (WGS) master records.</p><p><a href='../manual/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X
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Organism-specific databases
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Rat genome database<br/><a href='/database/91'>More..</a>RGDi | 1563983. Ubl4a.
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<p>Provides information on the location and the topology of the mature protein in the cell.</p><p><a href='../manual/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi
<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti
<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti
Cytoplasm<p>Describes post-translational modifications (PTMs) and/or processing events.</p><p><a href='../manual/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi
Molecule processing
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | Actions |
|---|
| <p>Describes the extent of a polypeptide chain in the mature protein following processing.</p><p><a href='../manual/chain' target='_top'>More...</a></p>Chaini | 1 – 157 | 157 | Ubiquitin-like protein 4A |  | PRO_0000403739 | Add
BLAST |
Amino acid modifications
<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi
PhosphoproteinProteomic databases
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PaxDb, a database of protein abundance averages across all three domains of life<br/><a href='/database/173'>More..</a>PaxDbi | B2GV38.
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PeptideAtlas<br/><a href='/database/71'>More..</a>PeptideAtlasi | B2GV38.
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PRoteomics IDEntifications database<br/><a href='/database/130'>More..</a>PRIDEi | B2GV38.
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PTM databases
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iPTMnet integrated resource for PTMs in systems biology context<br/><a href='/database/200'>More..</a>iPTMneti | B2GV38.
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Comprehensive resource for the study of human and mouse PTMs<br/><a href='/database/123'>More..</a>PhosphoSitei | B2GV38.
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<p>Provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.</p><p><a href='../manual/expression_section' target='_top'>More...</a></p>Expressioni
Gene expression databases
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Bgee dataBase for Gene Expression Evolution<br/><a href='/database/133'>More..</a>Bgeei | ENSRNOG00000037250.
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Genevisible search portal to normalized and curated expression data from Genevestigator<br/><a href='/database/194'>More..</a>Genevisiblei | B2GV38. RN.
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<p>Provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.</p><p><a href='../manual/interaction_section' target='_top'>More...</a></p>Interactioni
<p>Provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="/help/function_section">‘Function’</a> section).</p><p><a href='../manual/subunit_structure' target='_top'>More...</a></p>Subunit structurei
Component of the BAT3 complex, at least composed of BAG6/BAT3, UBL4A and GET4/TRC35.
Protein-protein interaction databases
<p>Provides information on the tertiary and secondary structure of a protein.</p><p><a href='../manual/structure_section' target='_top'>More...</a></p>Structurei
3D structure databases
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Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase<br/><a href='/database/159'>More..</a>ProteinModelPortali | B2GV38.
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SWISS-MODEL Repository - a database of annotated 3D protein structure models<br/><a href='/database/98'>More..</a>SMRi | B2GV38. Positions 1-74.
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Database of comparative protein structure models<br/><a href='/database/63'>More..</a>ModBasei | Search...
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MobiDB: a database of protein disorder and mobility annotations<br/><a href='/database/183'>More..</a>MobiDBi | Search...
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<p>Provides information on sequence similarities with other proteins and the domain(s) present in a protein.</p><p><a href='../manual/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi
Domains and Repeats
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | Actions |
|---|
| <p>Describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.</p><p><a href='../manual/domain' target='_top'>More...</a></p>Domaini | 1 – 76 | 76 | Ubiquitin-like
<p>Manual validated information which has been generated by the UniProtKB automatic annotation system.</p>
<p><a href="/manual/evidences#ECO:0000255">More…</a></p> Manual assertion according to rulesi |  | | Add
BLAST |
<p>Provides information about the sequence similarity with other proteins.</p><p><a href='../manual/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi
Contains 1
ubiquitin-like domain.
<p>Manual validated information which has been generated by the UniProtKB automatic annotation system.</p>
<p><a href="/manual/evidences#ECO:0000255">More…</a></p> Manual assertion according to rulesi
Phylogenomic databases
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evolutionary genealogy of genes: Non-supervised Orthologous Groups<br/><a href='/database/152'>More..</a>eggNOGi | KOG0001. Eukaryota.
COG5272. LUCA.
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Ensembl GeneTree<br/><a href='/database/162'>More..</a>GeneTreei | ENSGT00730000111022.
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The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms<br/><a href='/database/44'>More..</a>HOGENOMi | HOG000006827.
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The HOVERGEN Database of Homologous Vertebrate Genes<br/><a href='/database/45'>More..</a>HOVERGENi | HBG072205.
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InParanoid: Eukaryotic Ortholog Groups<br/><a href='/database/146'>More..</a>InParanoidi | B2GV38.
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Identification of Orthologs from Complete Genome Data<br/><a href='/database/137'>More..</a>OMAi | QRDYDRS.
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Database of Orthologous Groups<br/><a href='/database/143'>More..</a>OrthoDBi | EOG091G0XVA.
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Database for complete collections of gene phylogenies<br/><a href='/database/144'>More..</a>PhylomeDBi | B2GV38.
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TreeFam database of animal gene trees<br/><a href='/database/185'>More..</a>TreeFami | TF354228.
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Family and domain databases
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Integrated resource of protein families, domains and functional sites<br/><a href='/database/52'>More..</a>InterProi | IPR019956. Ubiquitin.
IPR029071. Ubiquitin-rel_dom.
IPR019954. Ubiquitin_CS.
IPR000626. Ubiquitin_dom.
[Graphical view] |
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Pfam protein domain database<br/><a href='/database/73'>More..</a>Pfami | PF00240. ubiquitin. 1 hit.
[Graphical view] |
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Protein Motif fingerprint database; a protein domain database<br/><a href='/database/82'>More..</a>PRINTSi | PR00348. UBIQUITIN.
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Simple Modular Architecture Research Tool; a protein domain database<br/><a href='/database/97'>More..</a>SMARTi | SM00213. UBQ. 1 hit.
[Graphical view] |
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Superfamily database of structural and functional annotation<br/><a href='/database/155'>More..</a>SUPFAMi | SSF54236. SSF54236. 1 hit.
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PROSITE; a protein domain and family database<br/><a href='/database/84'>More..</a>PROSITEi | PS00299. UBIQUITIN_1. 1 hit.
PS50053. UBIQUITIN_2. 1 hit.
[Graphical view] |
<p>Displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.</p><p><a href='../manual/sequences_section' target='_top'>More...</a></p>Sequencei
<p>Indicates if the <a href="/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.</p><p><a href='../manual/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.
Sequence databases
Genome annotation databases
<p>Is used to point to information related to entries and found in data collections other than UniProtKB.</p><p><a href='../manual/cross_references_section' target='_top'>More...</a></p>Cross-referencesi
Sequence databases
3D structure databases
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Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase<br/><a href='/database/159'>More..</a>ProteinModelPortali | B2GV38.
|
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SWISS-MODEL Repository - a database of annotated 3D protein structure models<br/><a href='/database/98'>More..</a>SMRi | B2GV38. Positions 1-74.
|
|
Database of comparative protein structure models<br/><a href='/database/63'>More..</a>ModBasei | Search...
|
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MobiDB: a database of protein disorder and mobility annotations<br/><a href='/database/183'>More..</a>MobiDBi | Search...
|
Protein-protein interaction databases
PTM databases
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iPTMnet integrated resource for PTMs in systems biology context<br/><a href='/database/200'>More..</a>iPTMneti | B2GV38.
|
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Comprehensive resource for the study of human and mouse PTMs<br/><a href='/database/123'>More..</a>PhosphoSitei | B2GV38.
|
Proteomic databases
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PaxDb, a database of protein abundance averages across all three domains of life<br/><a href='/database/173'>More..</a>PaxDbi | B2GV38.
|
|
PeptideAtlas<br/><a href='/database/71'>More..</a>PeptideAtlasi | B2GV38.
|
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PRoteomics IDEntifications database<br/><a href='/database/130'>More..</a>PRIDEi | B2GV38.
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Protocols and materials databases
Genome annotation databases
Organism-specific databases
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Comparative Toxicogenomics Database<br/><a href='/database/140'>More..</a>CTDi | 8266.
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Rat genome database<br/><a href='/database/91'>More..</a>RGDi | 1563983. Ubl4a.
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Phylogenomic databases
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evolutionary genealogy of genes: Non-supervised Orthologous Groups<br/><a href='/database/152'>More..</a>eggNOGi | KOG0001. Eukaryota.
COG5272. LUCA.
|
|
Ensembl GeneTree<br/><a href='/database/162'>More..</a>GeneTreei | ENSGT00730000111022.
|
|
The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms<br/><a href='/database/44'>More..</a>HOGENOMi | HOG000006827.
|
|
The HOVERGEN Database of Homologous Vertebrate Genes<br/><a href='/database/45'>More..</a>HOVERGENi | HBG072205.
|
|
InParanoid: Eukaryotic Ortholog Groups<br/><a href='/database/146'>More..</a>InParanoidi | B2GV38.
|
|
Identification of Orthologs from Complete Genome Data<br/><a href='/database/137'>More..</a>OMAi | QRDYDRS.
|
|
Database of Orthologous Groups<br/><a href='/database/143'>More..</a>OrthoDBi | EOG091G0XVA.
|
|
Database for complete collections of gene phylogenies<br/><a href='/database/144'>More..</a>PhylomeDBi | B2GV38.
|
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TreeFam database of animal gene trees<br/><a href='/database/185'>More..</a>TreeFami | TF354228.
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Miscellaneous databases
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Protein Ontology<br/><a href='/database/181'>More..</a>PROi | B2GV38.
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Gene expression databases
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Bgee dataBase for Gene Expression Evolution<br/><a href='/database/133'>More..</a>Bgeei | ENSRNOG00000037250.
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Genevisible search portal to normalized and curated expression data from Genevestigator<br/><a href='/database/194'>More..</a>Genevisiblei | B2GV38. RN.
|
Family and domain databases
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Integrated resource of protein families, domains and functional sites<br/><a href='/database/52'>More..</a>InterProi | IPR019956. Ubiquitin.
IPR029071. Ubiquitin-rel_dom.
IPR019954. Ubiquitin_CS.
IPR000626. Ubiquitin_dom.
[Graphical view] |
|
Pfam protein domain database<br/><a href='/database/73'>More..</a>Pfami | PF00240. ubiquitin. 1 hit.
[Graphical view] |
|
Protein Motif fingerprint database; a protein domain database<br/><a href='/database/82'>More..</a>PRINTSi | PR00348. UBIQUITIN.
|
|
Simple Modular Architecture Research Tool; a protein domain database<br/><a href='/database/97'>More..</a>SMARTi | SM00213. UBQ. 1 hit.
[Graphical view] |
|
Superfamily database of structural and functional annotation<br/><a href='/database/155'>More..</a>SUPFAMi | SSF54236. SSF54236. 1 hit.
|
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PROSITE; a protein domain and family database<br/><a href='/database/84'>More..</a>PROSITEi | PS00299. UBIQUITIN_1. 1 hit.
PS50053. UBIQUITIN_2. 1 hit.
[Graphical view] |
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ProtoNet; Automatic hierarchical classification of proteins<br/><a href='/database/85'>More..</a>ProtoNeti | Search...
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<p>Provides general information on the entry.</p><p><a href='../manual/entry_information_section' target='_top'>More...</a></p>Entry informationi
| <p>Provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.</p><p><a href='../manual/entry_name' target='_top'>More...</a></p>Entry namei | UBL4A_RAT |
| <p>Provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.</p><p><a href='../manual/accession_numbers' target='_top'>More...</a></p>Accessioni | B2GV38Primary (citable) accession number: B2GV38 |
| <p>Shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="help/canonical_and_isoforms">canonical sequence</a> are also displayed.</p><p><a href='../manual/entry_history' target='_top'>More...</a></p>Entry historyi | | Integrated into UniProtKB/Swiss-Prot: | January 11, 2011 | | Last sequence update: | June 10, 2008 | | Last modified: | September 7, 2016 | | This is version 56 of the entry and version 1 of the sequence. [Complete history] |
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| <p>Indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).</p><p><a href='../manual/entry_status' target='_top'>More...</a></p>Entry statusi | Reviewed (UniProtKB/Swiss-Prot) |
| Annotation program | Chordata Protein Annotation Program |
<p>Contains any relevant information that doesn’t fit in any other defined sections</p><p><a href='../manual/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi
<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi
Complete proteome, Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families
<p>Provides links to the UniProt Reference Clusters (<a href="/help/uniref">UniRef</a>). UniRef consists of clusters for UniProtKB sequences (including isoforms) and selected UniParc sequences, in order to obtain complete coverage of the sequence space at resolutions of 100%, 90% and 50% identity.</p><p><a href='../manual/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi
Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:| 100% | UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry. |
| 90% | UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence). |
| 50% | UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster. |
