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B2GUV6

- B2GUV6_RAT

UniProt

B2GUV6 - B2GUV6_RAT

Protein
Submitted name:

Protein Sesn2

Gene

Sesn2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 37 (01 Oct 2014)
      Sequence version 1 (10 Jun 2008)
      Previous versions | rss
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    Functioni

    GO - Biological processi

    1. regulation of response to reactive oxygen species Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Protein Sesn2Imported
    Submitted name:
    RCG31441Imported
    Submitted name:
    Similar to Sestrin 2 (Hi95)Imported
    Gene namesi
    Name:Sesn2Imported
    Synonyms:RGD1566319Imported
    ORF Names:rCG_31441Imported
    OrganismiRattus norvegicus (Rat)Imported
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
    ProteomesiUP000002494: Chromosome 5

    Organism-specific databases

    RGDi1566319. Sesn2.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: Ensembl
    2. nucleus Source: InterPro

    Expressioni

    Gene expression databases

    GenevestigatoriB2GUV6.

    Interactioni

    Protein-protein interaction databases

    STRINGi10116.ENSRNOP00000062295.

    Family & Domainsi

    Phylogenomic databases

    eggNOGiNOG312456.
    GeneTreeiENSGT00440000040103.
    HOVERGENiHBG054648.
    KOiK10141.
    OMAiASSWRHY.
    OrthoDBiEOG7SBNNF.

    Family and domain databases

    Gene3Di1.20.1290.10. 1 hit.
    InterProiIPR029032. AhpD-like.
    IPR006730. Sestrin.
    [Graphical view]
    PfamiPF04636. PA26. 1 hit.
    [Graphical view]
    SUPFAMiSSF69118. SSF69118. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B2GUV6-1 [UniParc]FASTAAdd to Basket

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    MIVADSECHG EIKGYLPFTR GGVAGPGTRE EHREGQARRG PRGPSAFIPV    50
    EEILREGAES LEQHLGLEAL MSSGRVDNLA VVMGLHPDYL SSFWRLHYLL 100
    LHTDGPLASS WRHYIAIMAA ARHQCSYLVG SHMTEFLQTG GDPEWLLGLH 150
    RAPEKLRKLS EINKLLAHRP WLITKEHIQA LLKTGEHSWS LAELIQALVL 200
    LTHCHCLASF VFGCGILPEG DAEGSPASQA PSPPSEQGGP PSRDPLNNSG 250
    GFEAARDIEA LMERMRQLQE SLLRDEGASQ EEMENRFELE KTESLLVTPS 300
    ADILEPSPHP DILCFVEDPT FGYEDFTRRG TQAPPTFRAQ DYTWEDHGYS 350
    LIQRLYPEGG QLLDEKFQVA YSLTYNTIAM HSGVDTSMLR RAVWNYIHCV 400
    FGIRYDDYDY GEVNQLLERN LKIYIKTVAC YPEKTTRRMY NLFWRHFRHS 450
    EKVHVNLLLL EARMQAALLY ALRAITRYMT 480
    Length:480
    Mass (Da):54,474
    Last modified:June 10, 2008 - v1
    Checksum:iD66B8D2654EA9DC6
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AABR06040248 Genomic DNA. No translation available.
    BC166423 mRNA. Translation: AAI66423.1.
    CH473968 Genomic DNA. Translation: EDL80638.1.
    RefSeqiNP_001102828.1. NM_001109358.2.
    UniGeneiRn.37672.

    Genome annotation databases

    EnsembliENSRNOT00000067455; ENSRNOP00000062295; ENSRNOG00000042785.
    GeneIDi502988.
    KEGGirno:502988.
    UCSCiRGD:1566319. rat.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AABR06040248 Genomic DNA. No translation available.
    BC166423 mRNA. Translation: AAI66423.1 .
    CH473968 Genomic DNA. Translation: EDL80638.1 .
    RefSeqi NP_001102828.1. NM_001109358.2.
    UniGenei Rn.37672.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10116.ENSRNOP00000062295.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSRNOT00000067455 ; ENSRNOP00000062295 ; ENSRNOG00000042785 .
    GeneIDi 502988.
    KEGGi rno:502988.
    UCSCi RGD:1566319. rat.

    Organism-specific databases

    CTDi 83667.
    RGDi 1566319. Sesn2.

    Phylogenomic databases

    eggNOGi NOG312456.
    GeneTreei ENSGT00440000040103.
    HOVERGENi HBG054648.
    KOi K10141.
    OMAi ASSWRHY.
    OrthoDBi EOG7SBNNF.

    Miscellaneous databases

    NextBioi 712999.

    Gene expression databases

    Genevestigatori B2GUV6.

    Family and domain databases

    Gene3Di 1.20.1290.10. 1 hit.
    InterProi IPR029032. AhpD-like.
    IPR006730. Sestrin.
    [Graphical view ]
    Pfami PF04636. PA26. 1 hit.
    [Graphical view ]
    SUPFAMi SSF69118. SSF69118. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: LungImported.
    2. "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
      Rat Genome Sequencing Project Consortium
      Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., Morgan M.
      , Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., Collins F.S.
      Nature 428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Brown NorwayImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BNImported.
    4. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BNImported.
    5. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: Brown NorwayImported.

    Entry informationi

    Entry nameiB2GUV6_RAT
    AccessioniPrimary (citable) accession number: B2GUV6
    Secondary accession number(s): D3ZFT9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 10, 2008
    Last sequence update: June 10, 2008
    Last modified: October 1, 2014
    This is version 37 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3