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B2GLW8 (SYR_KOCRD) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:KRH_09620
OrganismKocuria rhizophila (strain ATCC 9341 / DSM 348 / NBRC 103217 / DC2201) [Complete proteome] [HAMAP]
Taxonomic identifier378753 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeMicrococcaceaeKocuria

Protein attributes

Sequence length556 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 556556Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000095373

Regions

Motif132 – 14211"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
B2GLW8 [UniParc].

Last modified June 10, 2008. Version 1.
Checksum: 25633AB3EA88782E

FASTA55660,057
        10         20         30         40         50         60 
MTPEELSSAV SACLQDAVAA GELTVVDGVD LPEAKVERPK NRDHGDWATT VAMQVAKKVG 

        70         80         90        100        110        120 
RSPRDVAQIL SERLARVPGV KTVDIAGPGF LNITLDAAAA GGLAQSVVEQ GSAFGTGDAL 

       130        140        150        160        170        180 
AGTTINLEFV SANPTGPIHL GGTRWAAVGD SLARVLQAQG AEVVREYYFN DHGNQIDRFA 

       190        200        210        220        230        240 
RSLLARARGE AAPEDGYGGQ YISDVAQEVL ALHPDALESE DPQEVFRAAG VELMFAQIKS 

       250        260        270        280        290        300 
SLHEFGVDFD VFFHENSLFE DGQVEKLLEQ LRSSDSLYFA DGAWWLRSTE HGDDKDRVVI 

       310        320        330        340        350        360 
KSDGNAAYIA GDIAYFKNKR DRGADLCIYM LGADHHGYVA RLKAAAAALG DSPDAVEVLI 

       370        380        390        400        410        420 
GQMVNLVRDG EAVRMSKRAG TVVTMEDLVE VVGVDAARYS LTRYSVDSNI DIDLDVLTRR 

       430        440        450        460        470        480 
SNENPVFYVQ YAHARTCAVA RNAEAAGVRR TDDAGAPQFD AALLSHPREA DLLAALGQYP 

       490        500        510        520        530        540 
SVVAQAADFR EPHRVARHLE ALAGAYHRWY DACRVTPQGD GEVELVHHTR LWLNDAVRQV 

       550 
LANGLDLLGV SAPERM 

« Hide

References

[1]"Complete genome sequence of the soil actinomycete Kocuria rhizophila."
Takarada H., Sekine M., Kosugi H., Matsuo Y., Fujisawa T., Omata S., Kishi E., Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S.
J. Bacteriol. 190:4139-4146(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 9341 / DSM 348 / NBRC 103217 / DC2201.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP009152 Genomic DNA. Translation: BAG29309.1.
RefSeqYP_001854815.1. NC_010617.1.

3D structure databases

ProteinModelPortalB2GLW8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING378753.KRH_09620.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAG29309; BAG29309; KRH_09620.
GeneID6239209.
KEGGkrh:KRH_09620.
PATRIC22182130. VBIKocRhi5258_0932.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMAQQEVFRS.
OrthoDBEOG6JB13C.

Enzyme and pathway databases

BioCycKRHI378753:GJ8F-981-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_KOCRD
AccessionPrimary (citable) accession number: B2GLW8
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: June 10, 2008
Last modified: May 14, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries