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B2GJQ0 (B2GJQ0_KOCRD) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
UDP-N-acetylmuramoylalanine--D-glutamate ligase HAMAP MF_00639 RuleBase RU003664
EC=6.3.2.9 HAMAP MF_00639 RuleBase RU003664
Alternative name(s):
D-glutamic acid-adding enzyme HAMAP MF_00639
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase HAMAP MF_00639
Gene names
Name:murD HAMAP MF_00639 EMBL BAG29831.1
Ordered Locus Names:KRH_14840
OrganismKocuria rhizophila (strain ATCC 9341 / DSM 348 / NBRC 103217 / DC2201) [Complete proteome] [HAMAP]
Taxonomic identifier378753 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Kocuria

Protein attributes

Sequence length513 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) By similarity. HAMAP MF_00639 RuleBase RU003664 SAAS SAAS005762

Catalytic activity

ATP + UDP-N-acetylmuramoyl-L-alanine + glutamate = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate. HAMAP MF_00639 RuleBase RU003664 SAAS SAAS005762

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00639 RuleBase RU003664 SAAS SAAS005762

Subcellular location

Cytoplasm By similarity HAMAP MF_00639 RuleBase RU003664 SAAS SAAS005762.

Sequence similarities

Belongs to the MurCDEF family. HAMAP MF_00639 RuleBase RU003630

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding150 – 1567ATP By similarity HAMAP MF_00639

Sequences

Sequence LengthMass (Da)Tools
B2GJQ0 [UniParc].

Last modified June 10, 2008. Version 1.
Checksum: 353241883737999B

FASTA51353,936
        10         20         30         40         50         60 
MMHASNDNPI LDTPRLAGLT SWDAPWAGLR VVVAGIGVSG FAAADTLIEL GAKVTVVDAG 

        70         80         90        100        110        120 
DTERNRQSAD TLKIVGASDV VLGPDAMAAV PDVAGQRPEL VVTSPGIRPT SSLLTAAREE 

       130        140        150        160        170        180 
GIQIWGDVEL AWRVNRREGR KSPEWLCITG TNGKTTTVGM TASILQAAGL KAVAVGNVGT 

       190        200        210        220        230        240 
PILDALRDPV EYDVLAVELS SFQLHWMHSV SPLASAVLNV AEDHVDWHGS YENYRADKSR 

       250        260        270        280        290        300 
VYENTRVACV YNADQPGAEE LVEAADVVEG CRAVGFTTQH PGLSMVGVVE DLLVDRAFVA 

       310        320        330        340        350        360 
DRARTAAELG SVSDTGPIPT RHGVANALAA AALARAAGVE PEAVRDGLRA HHPGDHRIQL 

       370        380        390        400        410        420 
VAETDGVRWI NDSKATNPHA AEASLSAFDP VVWIAGGLSK GVTYDELVAR HAQRLRAVVV 

       430        440        450        460        470        480 
IGTDDAALLD ALARLAPDVP VLHATPGAGP DSAAGDPADG QEAMRRAVRL AHEHAAAQDT 

       490        500        510 
VLMAPAAASM DQFSDYAERG HAFIRSVHEE LGI

« Hide

References

[1]"Complete genome sequence of the soil actinomycete Kocuria rhizophila."
Takarada H., Sekine M., Kosugi H., Matsuo Y., Fujisawa T., Omata S., Kishi E., Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S.
J. Bacteriol. 190:4139-4146(2008) [PubMed: 18408034] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP009152 Genomic DNA. Translation: BAG29831.1.
RefSeqYP_001855337.1. NC_010617.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB2GJQ0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6239415.
GenomeReviewsGene locus KRH_14840 in contig AP009152_GR.
KEGGkrh:KRH_14840.
PATRIC22183250. VBIKocRhi5258_1476.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG750024.
OMAACASWDM.
ProtClustDBCLSK959755.

Family and domain databases

HAMAPMF_00639. MurD.
[Tree]
InterProIPR004101. Mur_ligase_C.
IPR013221. Mur_ligase_cen.
IPR016040. NAD(P)-bd_dom.
IPR005762. UDP-N-AcMur-Glu_ligase.
[Graphical view]
Gene3DG3DSA:3.90.190.20. Mur_ligase_C. 1 hit.
G3DSA:3.40.1190.10. Mur_ligase_cen. 1 hit.
G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KOK01925.
PANTHERPTHR23135:SF2. PTHR23135:SF2. 1 hit.
PfamPF02875. Mur_ligase_C. 1 hit.
PF08245. Mur_ligase_M. 1 hit.
[Graphical view]
SUPFAMSSF53244. Mur_ligase_C. 1 hit.
SSF53623. Mur_ligase_cen. 1 hit.
TIGRFAMsTIGR01087. MurD. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB2GJQ0_KOCRD
AccessionPrimary (citable) accession number: B2GJQ0
Entry history
Integrated into UniProtKB/TrEMBL: June 10, 2008
Last sequence update: June 10, 2008
Last modified: December 14, 2011
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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