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Protein

Pseudouridine synthase

Gene

rluD

Organism
Kocuria rhizophila (strain ATCC 9341 / DSM 348 / NBRC 103217 / DC2201)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil.UniRule annotation

Catalytic activityi

RNA uridine = RNA pseudouridine.UniRule annotation

GO - Molecular functioni

  1. pseudouridine synthase activity Source: InterPro
  2. RNA binding Source: InterPro

GO - Biological processi

  1. pseudouridine synthesis Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotation

Enzyme and pathway databases

BioCyciKRHI378753:GJ8F-1508-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Pseudouridine synthaseUniRule annotation (EC:5.4.99.-UniRule annotation)
Gene namesi
Name:rluDImported
Ordered Locus Names:KRH_14720Imported
OrganismiKocuria rhizophila (strain ATCC 9341 / DSM 348 / NBRC 103217 / DC2201)Imported
Taxonomic identifieri378753 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeMicrococcaceaeKocuria
ProteomesiUP000008838 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi378753.KRH_14720.

Structurei

3D structure databases

ProteinModelPortaliB2GJN8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase RluA family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0564.
HOGENOMiHOG000275919.
KOiK06180.
OMAiNETHNEL.
OrthoDBiEOG6P070X.

Family and domain databases

Gene3Di3.10.290.10. 1 hit.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR006225. PsdUridine_synth_RluC/D.
IPR006224. PsdUridine_synth_RluC/D_CS.
IPR006145. PsdUridine_synth_RsuA/RluD.
IPR002942. S4_RNA-bd.
[Graphical view]
PfamiPF00849. PseudoU_synth_2. 1 hit.
[Graphical view]
SMARTiSM00363. S4. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00005. rluA_subfam. 1 hit.
PROSITEiPS01129. PSI_RLU. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B2GJN8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTAERTRPTG SEPQFDTTRF TVPPEQDGLR LDAAVAAWTG LSRSAAAQLC
60 70 80 90 100
AEQRVSHRGS PVAKSHRVAV SETYTVEVPV PEDPHRIAPQ HVPDLRLVHV
110 120 130 140 150
EPSYVVVDKP AGVAAHPSPG WKGPTVVGAL AGAGISVATS GAPERQGIVH
160 170 180 190 200
RLDVGTSGLM VVAREEGAYS QLKRAFKERT VTKVYHAVVQ GIPDPLKGTI
210 220 230 240 250
DAPIGRHPGH EWRFAVMEDG RNSVTHYEVL EAFGRASLVE VHLETGRTHQ
260 270 280 290 300
IRVHFSALQY PCCGDLTYGA DPALSAGLGL TRQWLHAKRL GFTSPATGQH
310 320
VEYESPYPTD LAYAVETLRE GGPRL
Length:325
Mass (Da):35,095
Last modified:June 9, 2008 - v1
Checksum:iA90C00BF71794348
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP009152 Genomic DNA. Translation: BAG29819.1.
RefSeqiWP_012398540.1. NC_010617.1.
YP_001855325.1. NC_010617.1.

Genome annotation databases

EnsemblBacteriaiBAG29819; BAG29819; KRH_14720.
KEGGikrh:KRH_14720.
PATRICi22183226. VBIKocRhi5258_1464.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP009152 Genomic DNA. Translation: BAG29819.1.
RefSeqiWP_012398540.1. NC_010617.1.
YP_001855325.1. NC_010617.1.

3D structure databases

ProteinModelPortaliB2GJN8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi378753.KRH_14720.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAG29819; BAG29819; KRH_14720.
KEGGikrh:KRH_14720.
PATRICi22183226. VBIKocRhi5258_1464.

Phylogenomic databases

eggNOGiCOG0564.
HOGENOMiHOG000275919.
KOiK06180.
OMAiNETHNEL.
OrthoDBiEOG6P070X.

Enzyme and pathway databases

BioCyciKRHI378753:GJ8F-1508-MONOMER.

Family and domain databases

Gene3Di3.10.290.10. 1 hit.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR006225. PsdUridine_synth_RluC/D.
IPR006224. PsdUridine_synth_RluC/D_CS.
IPR006145. PsdUridine_synth_RsuA/RluD.
IPR002942. S4_RNA-bd.
[Graphical view]
PfamiPF00849. PseudoU_synth_2. 1 hit.
[Graphical view]
SMARTiSM00363. S4. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00005. rluA_subfam. 1 hit.
PROSITEiPS01129. PSI_RLU. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 9341 / DSM 348 / NBRC 103217 / DC2201Imported.

Entry informationi

Entry nameiB2GJN8_KOCRD
AccessioniPrimary (citable) accession number: B2GJN8
Entry historyi
Integrated into UniProtKB/TrEMBL: June 9, 2008
Last sequence update: June 9, 2008
Last modified: March 31, 2015
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.