B2GI90 (B2GI90_KOCRD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Dihydroorotase RuleBase RU003441
EC=3.5.2.3 RuleBase RU003441

Gene names

Name:	pyrC EMBL BAG29682.1
Ordered Locus Names:	KRH_13350

Organism

Kocuria rhizophila (strain ATCC 9341 / DSM 348 / NBRC 103217 / DC2201) [Complete proteome] [HAMAP]

Taxonomic identifier

378753 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Kocuria

Protein attributes

Sequence length	436 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(S)-dihydroorotate + H2O = N-carbamoyl-L-aspartate. RuleBase RU003441 SAAS SAAS002195
Cofactor	Binds 2 zinc ions per subunit By similarity. RuleBase RU003441 SAAS SAAS002195
Pathway	Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 3/3. RuleBase RU003441 SAAS SAAS002195
Subunit structure	Homodimer By similarity. SAAS SAAS002195
Sequence similarities	Belongs to the DHOase family. Type 2 subfamily. RuleBase RU003441

Ontologies

Keywords
Biological process	Pyrimidine biosynthesis RuleBase RU003441 SAAS SAAS002195
Ligand	Metal-binding RuleBase RU003441 SAAS SAAS002195 Zinc RuleBase RU003441 SAAS SAAS002195
Molecular function	Hydrolase SAAS SAAS002195 RuleBase RU003441 EMBL BAG29682.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pyrimidine nucleotide biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	dihydroorotase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B2GI90 [UniParc]. Last modified June 10, 2008. Version 1. Checksum: EB71415F7CB25A2E	FASTA	436	46,542
	10 20 30 40 50 60 MSTYLISNAR PEGGDPSDLL VVDGTVTAVG APGSLDVPED AEVIDATGLI ALPGLVDMHT 70 80 90 100 110 120 HLREPGREDA ETVETGTRAA ARGGYTAVFA MANSNPVADT AGVVEQVWQL GRDAGWADVH 130 140 150 160 170 180 PVGAVTVGLE GERLAEIRAM AESRAAVRMF SDDGKCVHDP VLMRRALEYV KAFDGIIAQH 190 200 210 220 230 240 AQEPRLTEGA QMNEGAVSAD LGLAGWPAVA EEAIIARDVL LAQHVDSRLH ICHLSTAGSV 250 260 270 280 290 300 EIVRWAKERG VTVTAEATPH HLLLTDELVR TFDPVYKVNP PLRTDEDVQA LRRAVAEGTI 310 320 330 340 350 360 DVIGTDHAPH TAEDKECEWS WAAHGMTGLE TALAVVQHTL VDTGLIGWQR VAQIMSRRPA 370 380 390 400 410 420 EILGLTDQGR ELAPGAPANI VLWDPTGATP VDPSRHASKA RNSPYRGMTL PGAVRATFYR 430 GHPVVRDGEL ATPLAR

References

[1]

"Complete genome sequence of the soil actinomycete Kocuria rhizophila." Takarada H., Sekine M., Kosugi H., Matsuo Y., Fujisawa T., Omata S., Kishi E., Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S. J. Bacteriol. 190:4139-4146(2008) [PubMed: 18408034] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP009152 Genomic DNA. Translation: BAG29682.1.
RefSeq	YP_001855188.1. NC_010617.1.
3D structure databases
ProteinModelPortal	B2GI90.
ModBase	Search...
Protein-protein interaction databases
STRING	B2GI90.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6238483.
GenomeReviews	Gene locus KRH_13350 in contig AP009152_GR.
KEGG	krh:KRH_13350.
PATRIC	22182932. VBIKocRhi5258_1319.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG724623.
OMA	GIFAEKE.
ProtClustDB	PRK09357.
Family and domain databases
HAMAP	MF_00220_B. PyrC_type2_B. [Tree]
InterPro	IPR006680. Amidohydro_1. IPR004722. DHOase. IPR002195. Dihydroorotase_CS. IPR011059. Metal-dep_hydrolase_composite. [Graphical view]
KO	K01465.
Pfam	PF01979. Amidohydro_1. 1 hit. [Graphical view]
SUPFAM	SSF51338. Metalo_hydrolase. 1 hit.
TIGRFAMs	TIGR00857. PyrC_multi. 1 hit.
PROSITE	PS00483. DIHYDROOROTASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B2GI90_KOCRD

Accession

Primary (citable) accession number: B2GI90

Entry history

Integrated into UniProtKB/TrEMBL:	June 10, 2008
Last sequence update:	June 10, 2008
Last modified:	December 14, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)