B2GHG2 (B2GHG2_KOCRD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Cobalamin-independent methionine synthase EMBL BAG30438.1
EC=2.1.1.14 EMBL BAG30438.1

Gene names

Name:	metE EMBL BAG30438.1
Ordered Locus Names:	KRH_20910

Organism

Kocuria rhizophila (strain ATCC 9341 / DSM 348 / NBRC 103217 / DC2201) [Complete proteome] [HAMAP]

Taxonomic identifier

378753 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Kocuria

Protein attributes

Sequence length	812 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation By similarity. SAAS SAAS013215
Catalytic activity	5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine = tetrahydropteroyltri-L-glutamate + L-methionine. SAAS SAAS013215
Pathway	Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-methionine from L-homocysteine (MetE route): step 1/1. SAAS SAAS013215

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Methionine biosynthesis SAAS SAAS013215
Ligand	Metal-binding SAAS SAAS013215 Zinc SAAS SAAS013215
Molecular function	Methyltransferase SAAS SAAS013215 EMBL BAG30438.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	methionine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity Inferred from electronic annotation. Source: EC zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B2GHG2 [UniParc]. Last modified June 10, 2008. Version 1. Checksum: A46297D950FDB8AD	FASTA	812	87,201
	10 20 30 40 50 60 MTVTNPATLP AATILGYPRI GPDRELKRAL EAHWKDPARH PASTVVDTLG ALRERTTLRL 70 80 90 100 110 120 RELGLGAEHA IPSEGFAVDH VLDTALALGA VPARFTADGY SPAAPDTPEG IGLLTALSRG 130 140 150 160 170 180 TDRLEPLEMT KWFDTNYHYY VPEIGPDTPL SAHPESLVAR YLDTLRRTGV RTRPVLVGPV 190 200 210 220 230 240 TLLLLSRPET TDDAPVDPLG RLEDVVGLYV RILSELAAAG VQWVQLDEPA LAADGWAVER 250 260 270 280 290 300 TEIVAAVESA YRRLTFPADR PAALVTVGYG DAGGDALLAL ARTDAEALAV DLDRGDVPGA 310 320 330 340 350 360 EALRAWGERP VVAGVVGGRT VWRTDLAGAT DTLDRLRAAA RGPVAVGTAT PLLHVPHDVT 370 380 390 400 410 420 QETGLDPDVR SWVAFADQKV TEVVELARGV EHGWEAITQT LETDARIRAA RAAHPATHRP 430 440 450 460 470 480 EVRERTAAVR GEDRVRASAV ERRAAQHERL RLPLLPTTTI GSFPQTTEIR ATRAAHRAGR 490 500 510 520 530 540 LDDAAYTEAI RREIARTVRA QEELGLDVLV HGEPERNDMV QYFAEALDGF ATTRHGWVQS 550 560 570 580 590 600 YGSRCTRPSI LFGDVSRPAP ITVDWTGYAA SLTDRPVKGM LTGPVTILAW SFVRDDAPAA 610 620 630 640 650 660 EVADQVALAL RDEITDLEAA GTAVVQVDEP ALRELLPLRE ADRPAYLEWS VGSFRLATGA 670 680 690 700 710 720 AATDTQIHTH LCYSEFETVL DAIEGLDADV TTLEASRSGS GIVDGLAAAD FPRDVGPGVW 730 740 750 760 770 780 DIHSPRVPTF EEVAGRVRHA AHAIGADRVW VNPDCGLKTR AWPETRAALD RLVAAAVTVR 790 800 810 GELARADRDG QGNDAARAVP PGTAPAGAAA TR

References

[1]

"Complete genome sequence of the soil actinomycete Kocuria rhizophila." Takarada H., Sekine M., Kosugi H., Matsuo Y., Fujisawa T., Omata S., Kishi E., Shimizu A., Tsukatani N., Tanikawa S., Fujita N., Harayama S. J. Bacteriol. 190:4139-4146(2008) [PubMed: 18408034] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP009152 Genomic DNA. Translation: BAG30438.1.
RefSeq	YP_001855944.1. NC_010617.1.
3D structure databases
ProteinModelPortal	B2GHG2.
ModBase	Search...
Protein-protein interaction databases
STRING	B2GHG2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6239584.
GenomeReviews	Gene locus KRH_20910 in contig AP009152_GR.
KEGG	krh:KRH_20910.
PATRIC	22184542. VBIKocRhi5258_2104.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG287495.
OMA	RNIWRAN.
ProtClustDB	PRK05222.
Family and domain databases
InterPro	IPR013215. Cbl-indep_Met_Synth_N. IPR002629. Methionine_synth. [Graphical view]
KO	K00549.
Pfam	PF08267. Meth_synt_1. 1 hit. PF01717. Meth_synt_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B2GHG2_KOCRD

Accession

Primary (citable) accession number: B2GHG2

Entry history

Integrated into UniProtKB/TrEMBL:	June 10, 2008
Last sequence update:	June 10, 2008
Last modified:	December 14, 2011
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)