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B2GEF7 (FENR_LACF3) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 30. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferredoxin--NADP reductase
Short name=FNR
Short name=Fd-NADP+ reductase
EC=1.18.1.2
Gene names
Ordered Locus Names:LAF_1703
OrganismLactobacillus fermentum (strain NBRC 3956 / LMG 18251) [Complete proteome] [HAMAP]
Taxonomic identifier334390 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Lactobacillales › Lactobacillaceae › Lactobacillus

Protein attributes

Sequence length330 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH. HAMAP MF_01685

Cofactor

Binds 1 FAD per subunit By similarity. HAMAP MF_01685

Subunit structure

Homodimer By similarity. HAMAP MF_01685

Sequence similarities

Belongs to the ferredoxin--NADP reductase type 2 family.

Ontologies

Keywords
   LigandFAD
Flavoprotein
NADP
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functionferredoxin-NADP+ reductase activity

Inferred from electronic annotation. Source: EC

flavin adenine dinucleotide binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 330330Ferredoxin--NADP reductase HAMAP MF_01685
PRO_0000364853

Sites

Binding site341FAD By similarity
Binding site421FAD By similarity
Binding site471FAD By similarity
Binding site871FAD; via amide nitrogen and carbonyl oxygen By similarity
Binding site1211FAD; via amide nitrogen By similarity
Binding site2851FAD By similarity
Binding site3251FAD By similarity

Sequences

Sequence LengthMass (Da)Tools
B2GEF7 [UniParc].

Last modified June 10, 2008. Version 1.
Checksum: 8F7D2B82F5D2338B

FASTA33035,670
        10         20         30         40         50         60 
MEERYDVTII GGGPAGMFAA FYCGLHQLKA QLIEALPQLG GQPAALYPEK RVWDVAGKAG 

        70         80         90        100        110        120 
VTGQELADDL AAQIEVAPVD QFLGEKVTDV VKEDDGSFTI HSAKRTSTSK SIVIAMGNGA 

       130        140        150        160        170        180 
FSPRKLALPG AEELEGKQVR YFANHKEDFK DQRVAVLGGG DAAIDMALML EDVAEQVYLV 

       190        200        210        220        230        240 
HRRDAFRALE HTVAQLEAST IEKLTPYLPK DLTVNADQSV TLNLKKMRAD EERPLEVDKV 

       250        260        270        280        290        300 
LVNYGFTSNN AALKDWSLDL ASERGQIKVD QTMKTSVPGV YAIGDGVVYE GKVALIATGF 

       310        320        330 
GEAPTAITNL AKELYPDKRM AIHSSSMGIG

« Hide

References

[1]"Comparative genome analysis of Lactobacillus reuteri and Lactobacillus fermentum reveal a genomic island for reuterin and cobalamin production."
Morita H., Toh H., Fukuda S., Horikawa H., Oshima K., Suzuki T., Murakami M., Hisamatsu S., Kato Y., Takizawa T., Fukuoka H., Yoshimura T., Itoh K., O'Sullivan D.J., McKay L.L., Ohno H., Kikuchi J., Masaoka T., Hattori M.
DNA Res. 15:151-161(2008) [PubMed: 18487258] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NBRC 3956 / LMG 18251.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP008937 Genomic DNA. Translation: BAG28039.1.
RefSeqYP_001844519.1. NC_010610.1.

3D structure databases

ProteinModelPortalB2GEF7.
ModBaseSearch...

Protein-protein interaction databases

STRINGB2GEF7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6233029.
GenomeReviewsGene locus LAF_1703 in contig AP008937_GR.
KEGGlfe:LAF_1703.
PATRIC22227835. VBILacFer15497_1878.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG669726.
OMAYPNKQKL.
ProtClustDBCLSK2326607.

Family and domain databases

HAMAPMF_01685. FENR2.
[Tree]
InterProIPR013027. FAD_pyr_nucl-diS_OxRdtase.
IPR022890. Fd--NADP_Rdtase_type_2.
IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD.
IPR001327. Pyr_OxRdtase_NAD-bd_dom.
IPR000103. Pyridine_nuc-diS_OxRdtase_2.
[Graphical view]
KOK00384.
PANTHERPTHR22912:SF53. PTHR22912:SF53. 1 hit.
PfamPF00070. Pyr_redox. 1 hit.
PF07992. Pyr_redox_2. 1 hit.
[Graphical view]
PRINTSPR00368. FADPNR.
PR00469. PNDRDTASEII.
ProtoNetSearch...

Entry information

Entry nameFENR_LACF3
AccessionPrimary (citable) accession number: B2GEF7
Entry history
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: June 10, 2008
Last modified: January 25, 2012
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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