B2GC42 (B2GC42_LACF3) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Dihydrofolate reductase EMBL BAG27224.1

Gene names

Ordered Locus Names:

LAF_0888

Organism

Lactobacillus fermentum (strain NBRC 3956 / LMG 18251) [Complete proteome] [HAMAP]

Taxonomic identifier

334390 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Lactobacillaceae › Lactobacillus

Protein attributes

Sequence length	167 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the dihydrofolate reductase family. RuleBase RU004474

Ontologies

Keywords
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycine biosynthetic process Inferred from electronic annotation. Source: InterPro nucleotide biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	NADP binding Inferred from electronic annotation. Source: InterPro dihydrofolate reductase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B2GC42 [UniParc]. Last modified June 10, 2008. Version 1. Checksum: E0CB665354B2DBD4	FASTA	167	18,709
	10 20 30 40 50 60 MVKIAFIWAE DEAGWIGKDN DMPWHLSADL KHFKHLTSGH PVIMGKNTYL SLGRPLPKRT 70 80 90 100 110 120 NIVVTRQTTP IEGVTLVNGV NALTDLLANY GEDEEVFIIG GAHLFASTMS LATVLYRTVV 130 140 150 160 EGDHHGDVKM APIDYRTWQK VAERHLQATE SDPACTFEKW VLNVKQN

References

[1]

"Comparative genome analysis of Lactobacillus reuteri and Lactobacillus fermentum reveal a genomic island for reuterin and cobalamin production." Morita H., Toh H., Fukuda S., Horikawa H., Oshima K., Suzuki T., Murakami M., Hisamatsu S., Kato Y., Takizawa T., Fukuoka H., Yoshimura T., Itoh K., O'Sullivan D.J., McKay L.L., Ohno H., Kikuchi J., Masaoka T., Hattori M. DNA Res. 15:151-161(2008) [PubMed: 18487258] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NBRC 3956 / LMG 18251.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP008937 Genomic DNA. Translation: BAG27224.1.
RefSeq	YP_001843704.1. NC_010610.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B2GC42.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6232336.
GenomeReviews	Gene locus LAF_0888 in contig AP008937_GR.
KEGG	lfe:LAF_0888.
PATRIC	22225976. VBILacFer15497_0974.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG665708.
OMA	YITHILQ.
ProtClustDB	CLSK2326299.
Family and domain databases
InterPro	IPR012259. DHFR. IPR024072. DHFR-like_dom. IPR001796. DHFR_dom. [Graphical view]
Gene3D	G3DSA:3.40.430.10. G3DSA:3.40.430.10. 1 hit.
KO	K00287.
PANTHER	PTHR11549:SF1. DHFR. 1 hit.
Pfam	PF00186. DHFR_1. 1 hit. [Graphical view]
PIRSF	PIRSF000194. DHFR. 1 hit.
PRINTS	PR00070. DHFR.
SUPFAM	SSF53597. SSF53597. 1 hit.
PROSITE	PS51330. DHFR_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B2GC42_LACF3

Accession

Primary (citable) accession number: B2GC42

Entry history

Integrated into UniProtKB/TrEMBL:	June 10, 2008
Last sequence update:	June 10, 2008
Last modified:	January 25, 2012
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)