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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Lactobacillus fermentum (strain NBRC 3956 / LMG 18251)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei143GTPUniRule annotation1
Binding sitei147GTPUniRule annotation1
Binding sitei191GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi25 – 29GTPUniRule annotation5
Nucleotide bindingi112 – 114GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotation
Ordered Locus Names:LAF_0577Imported
OrganismiLactobacillus fermentum (strain NBRC 3956 / LMG 18251)Imported
Taxonomic identifieri334390 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
Proteomesi
  • UP000001697 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini17 – 209TubulinInterPro annotationAdd BLAST193
Domaini211 – 328Tubulin_CInterPro annotationAdd BLAST118

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000049094
KOiK03531
OMAiMRAVKGI
OrthoDBiPOG091H02KK

Family and domain databases

CDDicd02201 FtsZ_type1, 1 hit
Gene3Di3.30.1330.20, 1 hit
3.40.50.1440, 1 hit
HAMAPiMF_00909 FtsZ, 1 hit
InterProiView protein in InterPro
IPR000158 Cell_div_FtsZ
IPR020805 Cell_div_FtsZ_CS
IPR024757 FtsZ_C
IPR008280 Tub_FtsZ_C
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR037103 Tubulin/FtsZ_C_sf
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR003008 Tubulin_FtsZ_GTPase
PfamiView protein in Pfam
PF12327 FtsZ_C, 1 hit
PF00091 Tubulin, 1 hit
PRINTSiPR00423 CELLDVISFTSZ
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
TIGRFAMsiTIGR00065 ftsZ, 1 hit
PROSITEiView protein in PROSITE
PS01134 FTSZ_1, 1 hit
PS01135 FTSZ_2, 1 hit

Sequencei

Sequence statusi: Complete.

B2GB81-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDNATNEFDQ LHPTQAQIKV IGVGGGGGNA VNQMINENVE GVDFIVANTD
60 70 80 90 100
LQALEGSHAK TKLHLGPKLT RGLGAGSNPE VGAKAAQESE SDITKALEGA
110 120 130 140 150
DMVFVTAGMG GGTGTGAAPV IAKIAKDSGA LTVGVVTRPF SFEGTRRAKL
160 170 180 190 200
AAEGLENLEK NVDTLIVVSN DRLLEIIDKK TPMMEAFKEA DDVLRQGVEG
210 220 230 240 250
ISDLITNPGY INLDFADIRH TMTNQGAALM GIGAAGGDER AKEATKRAIS
260 270 280 290 300
SPLLEVSIDG AEHVLVNVTG GKDLSMTEAE DASSVIRQAA NTNVDITFGM
310 320 330 340 350
AIDETLNDEI RVTVIATGID KTKQGDEKPV EEVSQPAAQP VSQAPVQPQV
360 370 380 390 400
QAQPQASAAP APTSEFATTD DPFQNWNEDL GNELEGGARP NSFNHVKKPT
410 420
FSVQDDNLSN VDDGGEDLST PAFFKNRRK
Length:429
Mass (Da):45,111
Last modified:June 10, 2008 - v1
Checksum:iAC628950D973CCC5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008937 Genomic DNA Translation: BAG26913.1
RefSeqiWP_003686334.1, NC_010610.1

Genome annotation databases

EnsemblBacteriaiBAG26913; BAG26913; LAF_0577
GeneIDi6233683
KEGGilfe:LAF_0577

Similar proteinsi

Entry informationi

Entry nameiB2GB81_LACF3
AccessioniPrimary (citable) accession number: B2GB81
Entry historyiIntegrated into UniProtKB/TrEMBL: June 10, 2008
Last sequence update: June 10, 2008
Last modified: March 28, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
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Main funding by: National Institutes of Health