B2GAA4 (B2GAA4_LACF3) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase 2 HAMAP MF_01039
Short name=BPG-dependent PGAM 2 HAMAP MF_01039
Short name=PGAM 2 HAMAP MF_01039
Short name=Phosphoglyceromutase 2 HAMAP MF_01039
Short name=dPGM 2 HAMAP MF_01039
EC=5.4.2.1 HAMAP MF_01039

Gene names

Name:	gpmA2 HAMAP MF_01039
Ordered Locus Names:	LAF_0250

Organism

Lactobacillus fermentum (strain NBRC 3956 / LMG 18251) [Complete proteome] [HAMAP]

Taxonomic identifier

334390 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Lactobacillaceae › Lactobacillus

Protein attributes

Sequence length	225 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity. HAMAP MF_01039 RuleBase RU004512
Catalytic activity	2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP MF_01039 RuleBase RU004512 SAAS SAAS005952
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP MF_01039 RuleBase RU004512
Sequence similarities	Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily. HAMAP MF_01039

Ontologies

Keywords
Biological process	Glycolysis HAMAP MF_01039 SAAS SAAS005952
Molecular function	Isomerase HAMAP MF_01039 SAAS SAAS005952
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: HAMAP
Molecular function	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	9	1	Tele-phosphohistidine intermediate By similarity HAMAP MF_01039
	Active site	176	1	By similarity HAMAP MF_01039
	Site	60	1	Interaction with carboxyl group of phosphoglycerates By similarity HAMAP MF_01039

Sequences

	Sequence		Length	Mass (Da)
	B2GAA4 [UniParc]. Last modified June 10, 2008. Version 1. Checksum: 8DBD50E231F7047B	FASTA	225	25,728
	10 20 30 40 50 60 MTKLVMVRHG QSQANLDNRF TGWSDVPLTA KGIAQGKEVG AELAAREFSF TDVHTSYMKR 70 80 90 100 110 120 AIMTADYILE ALDQLYLPIH KTWRLNERHY GALSGLNKEA VKREVGEQQL HAWRRGFFAV 130 140 150 160 170 180 PPQLAHPAHD RRYDRLGVKE PLAESLEMCL ERILPYWQDQ VAPRLLAGHD QLIVAHGSTL 190 200 210 220 RALVKYIEGI SDDQIDQVEV LNGQPIIYQF DDHLVPVHKE ILMEE

References

[1]

"Comparative genome analysis of Lactobacillus reuteri and Lactobacillus fermentum reveal a genomic island for reuterin and cobalamin production." Morita H., Toh H., Fukuda S., Horikawa H., Oshima K., Suzuki T., Murakami M., Hisamatsu S., Kato Y., Takizawa T., Fukuoka H., Yoshimura T., Itoh K., O'Sullivan D.J., McKay L.L., Ohno H., Kikuchi J., Masaoka T., Hattori M. DNA Res. 15:151-161(2008) [PubMed: 18487258] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NBRC 3956 / LMG 18251.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP008937 Genomic DNA. Translation: BAG26586.1.
RefSeq	YP_001843066.1. NC_010610.1.
3D structure databases
ProteinModelPortal	B2GAA4.
ModBase	Search...
Protein-protein interaction databases
STRING	B2GAA4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6233354.
GenomeReviews	Gene locus LAF_0250 in contig AP008937_GR.
KEGG	lfe:LAF_0250.
PATRIC	22224536. VBILacFer15497_0281.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG658938.
OMA	ESTANRD.
ProtClustDB	CLSK2326081.
Family and domain databases
HAMAP	MF_01039. PGAM_GpmA. [Tree]
InterPro	IPR013078. His_Pase_superF_clade-1. IPR001345. PG/BPGM_mutase_AS. IPR005952. Phosphogly_mut1. [Graphical view]
KO	K01834.
PANTHER	PTHR11931. Phosphogly_mut1. 1 hit.
Pfam	PF00300. His_Phos_1. 1 hit. [Graphical view]
SMART	SM00855. PGAM. 1 hit. [Graphical view]
TIGRFAMs	TIGR01258. Pgm_1. 1 hit.
PROSITE	PS00175. PG_MUTASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B2GAA4_LACF3

Accession

Primary (citable) accession number: B2GAA4

Entry history

Integrated into UniProtKB/TrEMBL:	June 10, 2008
Last sequence update:	June 10, 2008
Last modified:	December 14, 2011
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)