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Protein
Submitted name:

Beta-galactosidase large subunit

Gene

LAF_0247

Organism
Lactobacillus fermentum (strain NBRC 3956 / LMG 18251)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. hydrolase activity, hydrolyzing O-glycosyl compounds Source: InterPro

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseUniRule annotationSAAS annotation, Hydrolase

Enzyme and pathway databases

BioCyciLFER334390:GJ2S-267-MONOMER.

Protein family/group databases

CAZyiGH2. Glycoside Hydrolase Family 2.

Names & Taxonomyi

Protein namesi
Submitted name:
Beta-galactosidase large subunitImported
Gene namesi
Ordered Locus Names:LAF_0247Imported
OrganismiLactobacillus fermentum (strain NBRC 3956 / LMG 18251)Imported
Taxonomic identifieri334390 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
ProteomesiUP000001697: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi334390.LAF_0247.

Structurei

3D structure databases

ProteinModelPortaliB2GAA1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 2 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG3250.
HOGENOMiHOG000111236.
KOiK01190.
OMAiPYQFGFR.
OrthoDBiEOG6XWV0T.

Family and domain databases

Gene3Di2.60.120.260. 1 hit.
2.60.40.320. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR008979. Galactose-bd-like.
IPR006101. Glyco_hydro_2.
IPR013812. Glyco_hydro_2/20_Ig-like.
IPR023232. Glyco_hydro_2_AS.
IPR023230. Glyco_hydro_2_CS.
IPR006102. Glyco_hydro_2_Ig-like.
IPR006104. Glyco_hydro_2_N.
IPR006103. Glyco_hydro_2_TIM.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF00703. Glyco_hydro_2. 1 hit.
PF02836. Glyco_hydro_2_C. 1 hit.
PF02837. Glyco_hydro_2_N. 1 hit.
[Graphical view]
PRINTSiPR00132. GLHYDRLASE2.
SUPFAMiSSF49303. SSF49303. 1 hit.
SSF49785. SSF49785. 1 hit.
SSF51445. SSF51445. 1 hit.
PROSITEiPS00719. GLYCOSYL_HYDROL_F2_1. 1 hit.
PS00608. GLYCOSYL_HYDROL_F2_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B2GAA1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEAELKWLDD PEVFRVNQLP AHSDHRFYRD QEEAALEKSS YVQNLNGRWG
60 70 80 90 100
FKFSKNPMER PVDFYKLDFD RNDFGEIEVP SEIELSNFAQ INYTNITMPW
110 120 130 140 150
TGKIYRRPAY TLGDNKEEGS FSQGQDNTVG SYVRHFTLAE GLKNHDVHVV
160 170 180 190 200
FEGVERAMYV WLNGHFIGYA EDSFTPSEFD LTPYLVDGDN LLAVEVYKHA
210 220 230 240 250
TSSWIEDQDM FRFSGIFRDV NLVAQPSIHV QDLKINARVA DDMKTGSLGL
260 270 280 290 300
VLKMVGQPGS VQVEVADQTG AAVLNRQLNA DGNWTMAPVQ LVGIHLWDNH
310 320 330 340 350
HPYLYQLTLT VRDATGRVVE VIPYQFGFRR VEIDQDKVLR LNGKRLIING
360 370 380 390 400
VNRHEWNCHR GRAVTIEDMH TDLGIFKENN INAVRTSHYP DQIPWYYLCD
410 420 430 440 450
REGIYMMAEN NLESHATWQK FGQDEPSYNV PGSLPQWKEA VVDRARSNYE
460 470 480 490 500
IFKNHTAILF WSVGNESYAG EDILAMNNYY KEVDDTRPVH YEGVVHTKEY
510 520 530 540 550
RDQISDFESW MYLPPKEVEA YLKKNPDKPF IECEYMHSMG NSVGGMGSYI
560 570 580 590 600
KLLDKYPQYC GGFIWDFVDQ AIEVVDPVTG QKSMRYGGDF DDHHADNEFS
610 620
GDGICFADRT PKPAMQEVKY YYGLHK
Length:626
Mass (Da):72,279
Last modified:June 10, 2008 - v1
Checksum:iD5C2409E3364D716
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008937 Genomic DNA. Translation: BAG26583.1.
RefSeqiYP_001843063.1. NC_010610.1.

Genome annotation databases

EnsemblBacteriaiBAG26583; BAG26583; LAF_0247.
GeneIDi6232392.
KEGGilfe:LAF_0247.
PATRICi22224530. VBILacFer15497_0278.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008937 Genomic DNA. Translation: BAG26583.1.
RefSeqiYP_001843063.1. NC_010610.1.

3D structure databases

ProteinModelPortaliB2GAA1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi334390.LAF_0247.

Protein family/group databases

CAZyiGH2. Glycoside Hydrolase Family 2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAG26583; BAG26583; LAF_0247.
GeneIDi6232392.
KEGGilfe:LAF_0247.
PATRICi22224530. VBILacFer15497_0278.

Phylogenomic databases

eggNOGiCOG3250.
HOGENOMiHOG000111236.
KOiK01190.
OMAiPYQFGFR.
OrthoDBiEOG6XWV0T.

Enzyme and pathway databases

BioCyciLFER334390:GJ2S-267-MONOMER.

Family and domain databases

Gene3Di2.60.120.260. 1 hit.
2.60.40.320. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR008979. Galactose-bd-like.
IPR006101. Glyco_hydro_2.
IPR013812. Glyco_hydro_2/20_Ig-like.
IPR023232. Glyco_hydro_2_AS.
IPR023230. Glyco_hydro_2_CS.
IPR006102. Glyco_hydro_2_Ig-like.
IPR006104. Glyco_hydro_2_N.
IPR006103. Glyco_hydro_2_TIM.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF00703. Glyco_hydro_2. 1 hit.
PF02836. Glyco_hydro_2_C. 1 hit.
PF02837. Glyco_hydro_2_N. 1 hit.
[Graphical view]
PRINTSiPR00132. GLHYDRLASE2.
SUPFAMiSSF49303. SSF49303. 1 hit.
SSF49785. SSF49785. 1 hit.
SSF51445. SSF51445. 1 hit.
PROSITEiPS00719. GLYCOSYL_HYDROL_F2_1. 1 hit.
PS00608. GLYCOSYL_HYDROL_F2_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Comparative genome analysis of Lactobacillus reuteri and Lactobacillus fermentum reveal a genomic island for reuterin and cobalamin production."
    Morita H., Toh H., Fukuda S., Horikawa H., Oshima K., Suzuki T., Murakami M., Hisamatsu S., Kato Y., Takizawa T., Fukuoka H., Yoshimura T., Itoh K., O'Sullivan D.J., McKay L.L., Ohno H., Kikuchi J., Masaoka T., Hattori M.
    DNA Res. 15:151-161(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NBRC 3956 / LMG 18251Imported.

Entry informationi

Entry nameiB2GAA1_LACF3
AccessioniPrimary (citable) accession number: B2GAA1
Entry historyi
Integrated into UniProtKB/TrEMBL: June 10, 2008
Last sequence update: June 10, 2008
Last modified: February 4, 2015
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.