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Protein

Exodeoxyribonuclease 7 small subunit

Gene

xseB

Organism
Lactobacillus reuteri (strain JCM 1112)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.UniRule annotation

Catalytic activityi

Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Exonuclease, Hydrolase, Nuclease

Enzyme and pathway databases

BioCyciLREU557433:GHNR-1174-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Exodeoxyribonuclease 7 small subunitUniRule annotation (EC:3.1.11.6UniRule annotation)
Alternative name(s):
Exodeoxyribonuclease VII small subunitUniRule annotation
Short name:
Exonuclease VII small subunitUniRule annotation
Gene namesi
Name:xseBUniRule annotation
Ordered Locus Names:LAR_1114
OrganismiLactobacillus reuteri (strain JCM 1112)
Taxonomic identifieri557433 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 9393Exodeoxyribonuclease 7 small subunitPRO_1000119935Add
BLAST

Interactioni

Subunit structurei

Heterooligomer composed of large and small subunits.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB2G848.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the XseB family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000228798.
KOiK03602.
OMAiCHDKLQH.
OrthoDBiEOG69KV31.

Family and domain databases

Gene3Di1.10.287.1040. 1 hit.
HAMAPiMF_00337. Exonuc_7_S.
InterProiIPR003761. Exonuc_VII_S.
[Graphical view]
PfamiPF02609. Exonuc_VII_S. 1 hit.
[Graphical view]
ProDomiPD028235. Exonuc_VII_S. 1 hit.
[Graphical view] [Entries sharing at least one domain]
TIGRFAMsiTIGR01280. xseB. 1 hit.

Sequencei

Sequence statusi: Complete.

B2G848-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATAKPTFEE QLAQLQQIVN HLEQGNVPLE EALQQFQEGI KLSKELQTKL
60 70 80 90
TNAEKTLGHL IDDNGDEKVY EKQTDDPSNN GGGNRGFGSA DEQ
Length:93
Mass (Da):10,268
Last modified:June 10, 2008 - v1
Checksum:i8523E86F3A74C99C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP007281 Genomic DNA. Translation: BAG25630.1.
RefSeqiWP_003663862.1. NC_010609.1.

Genome annotation databases

EnsemblBacteriaiBAG25630; BAG25630; LAR_1114.
GeneIDi5188164.
KEGGilrf:LAR_1114.
PATRICi22259744. VBILacReu111271_1229.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP007281 Genomic DNA. Translation: BAG25630.1.
RefSeqiWP_003663862.1. NC_010609.1.

3D structure databases

ProteinModelPortaliB2G848.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAG25630; BAG25630; LAR_1114.
GeneIDi5188164.
KEGGilrf:LAR_1114.
PATRICi22259744. VBILacReu111271_1229.

Phylogenomic databases

HOGENOMiHOG000228798.
KOiK03602.
OMAiCHDKLQH.
OrthoDBiEOG69KV31.

Enzyme and pathway databases

BioCyciLREU557433:GHNR-1174-MONOMER.

Family and domain databases

Gene3Di1.10.287.1040. 1 hit.
HAMAPiMF_00337. Exonuc_7_S.
InterProiIPR003761. Exonuc_VII_S.
[Graphical view]
PfamiPF02609. Exonuc_VII_S. 1 hit.
[Graphical view]
ProDomiPD028235. Exonuc_VII_S. 1 hit.
[Graphical view] [Entries sharing at least one domain]
TIGRFAMsiTIGR01280. xseB. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Comparative genome analysis of Lactobacillus reuteri and Lactobacillus fermentum reveal a genomic island for reuterin and cobalamin production."
    Morita H., Toh H., Fukuda S., Horikawa H., Oshima K., Suzuki T., Murakami M., Hisamatsu S., Kato Y., Takizawa T., Fukuoka H., Yoshimura T., Itoh K., O'Sullivan D.J., McKay L.L., Ohno H., Kikuchi J., Masaoka T., Hattori M.
    DNA Res. 15:151-161(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JCM 1112.

Entry informationi

Entry nameiEX7S_LACRJ
AccessioniPrimary (citable) accession number: B2G848
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: June 10, 2008
Last modified: November 11, 2015
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.