B2G592 (DEOD_LACRJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Purine nucleoside phosphorylase DeoD-type
Short name=PNP
EC=2.4.2.1

Gene names

Name:	deoD
Ordered Locus Names:	LAR_0108

Organism

Lactobacillus reuteri (strain JCM 1112) [Complete proteome] [HAMAP]

Taxonomic identifier

557433 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Lactobacillales › Lactobacillaceae › Lactobacillus › Lactobacillus reuteri

Protein attributes

Sequence length	236 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Purine nucleoside + phosphate = purine + alpha-D-ribose 1-phosphate. HAMAP-Rule MF_01627
Subunit structure	Homohexamer By similarity.
Sequence similarities	Belongs to the PNP/UDP phosphorylase family.

Ontologies

Keywords
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	purine nucleoside metabolic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	purine-nucleoside phosphorylase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 236	236	Purine nucleoside phosphorylase DeoD-type HAMAP-Rule MF_01627		PRO_1000186209

Sequences

	Sequence		Length	Mass (Da)
	B2G592 [UniParc]. Last modified October 14, 2008. Version 1. Checksum: 3CBA0DBDB8F45770	FASTA	236	25,751
	10 20 30 40 50 60 MSTHINAKMG DYADTVLLPG DPLRAKYIAE NFLENVKQVN SVRNAFGYTG EYKGHRISVQ 70 80 90 100 110 120 GSGMGIPSMS IYINELVREF GVKTIIRVGS CGGIAPDVHV RDVLLAQGSS TDSAVTVNTF 130 140 150 160 170 180 GPGFHYAPLA DFKLLDTAYH VAGKLGIETK VGDIFAADRF YNDELDMEKL RDYGILGTEM 190 200 210 220 230 ESAGLYLLAA KLHFRALSVL TVSDLIFGDE KATAEERERT FNDMINISLE TAIAGK

References

[1]

"Comparative genome analysis of Lactobacillus reuteri and Lactobacillus fermentum reveal a genomic island for reuterin and cobalamin production." Morita H., Toh H., Fukuda S., Horikawa H., Oshima K., Suzuki T., Murakami M., Hisamatsu S., Kato Y., Takizawa T., Fukuoka H., Yoshimura T., Itoh K., O'Sullivan D.J., McKay L.L., Ohno H., Kikuchi J., Masaoka T., Hattori M. DNA Res. 15:151-161(2008) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: JCM 1112.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP007281 Genomic DNA. Translation: BAG24624.1.
RefSeq	YP_001841104.1. NC_010609.1.
3D structure databases
ProteinModelPortal	B2G592.
SMR	B2G592. Positions 1-232.
ModBase	Search...
Protein-protein interaction databases
STRING	557433.LAR_0108.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAG24624; BAG24624; LAR_0108.
GeneID	6230170.
KEGG	lrf:LAR_0108.
PATRIC	22257398. VBILacReu111271_0117.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0813.
HOGENOM	HOG000274896.
KO	K03784.
OMA	SFETHAF.
ProtClustDB	CLSK2326020.
Enzyme and pathway databases
BioCyc	LREU557433:GHNR-109-MONOMER.
Family and domain databases
HAMAP	MF_01627. Pur_nucleosid_phosp.
InterPro	IPR004402. DeoD-type. IPR018017. Nucleoside_phosphorylase. IPR018016. Nucleoside_phosphorylase_CS. IPR000845. Nucleoside_phosphorylase_d. [Graphical view]
PANTHER	PTHR21234. PTHR21234. 1 hit.
Pfam	PF01048. PNP_UDP_1. 1 hit. [Graphical view]
TIGRFAMs	TIGR00107. deoD. 1 hit.
PROSITE	PS01232. PNP_UDP_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DEOD_LACRJ

Accession

Primary (citable) accession number: B2G592

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	October 14, 2008
Last modified:	May 1, 2013
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program