B2FM88 (PHS_STRMK) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative pterin-4-alpha-carbinolamine dehydratase
Short name=PHS
EC=4.2.1.96

Alternative name(s):
4-alpha-hydroxy-tetrahydropterin dehydratase
Pterin carbinolamine dehydratase
Short name=PCD

Gene names

Ordered Locus Names:

Smlt3243

Organism

Stenotrophomonas maltophilia (strain K279a) [Complete proteome] [HAMAP]

Taxonomic identifier

522373 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Xanthomonadales › Xanthomonadaceae › Stenotrophomonas › Stenotrophomonas maltophilia group

Protein attributes

Sequence length	116 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin + H2O. HAMAP MF_00434
Sequence similarities	Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

Ontologies

Keywords
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tetrahydrobiopterin biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	4-alpha-hydroxytetrahydrobiopterin dehydratase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 116	116	Putative pterin-4-alpha-carbinolamine dehydratase HAMAP MF_00434		PRO_1000192939

Sequences

	Sequence		Length	Mass (Da)
	B2FM88 [UniParc]. Last modified June 10, 2008. Version 1. Checksum: 44677C7BB3B492B1	FASTA	116	12,887
	10 20 30 40 50 60 MADLIPLAQA RCVPRKGSDH KLGEARLAEL LPQIPGWELS EGGQALSRTF RFKDYYATMA 70 80 90 100 110 FVNALAWIAH REDHHPDLGV HYDRAVVRFS THDVGGLSEN DFICAAKTSA LTEQLP

References

[1]

"The complete genome, comparative and functional analysis of Stenotrophomonas maltophilia reveals an organism heavily shielded by drug resistance determinants." Crossman L.C., Gould V.C., Dow J.M., Vernikos G.S., Okazaki A., Sebaihia M., Saunders D., Arrowsmith C., Carver T., Peters N., Adlem E., Kerhornou A., Lord A., Murphy L., Seeger K., Squares R., Rutter S., Quail M.A. , Rajandream M.A., Harris D., Churcher C., Bentley S.D., Parkhill J., Thomson N.R., Avison M.B. Genome Biol. 9:R74.1-R74.13(2008) [PubMed: 18419807] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K279a.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM743169 Genomic DNA. Translation: CAQ46683.1.
RefSeq	YP_001972974.1. NC_010943.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B2FM88.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6393546.
GenomeReviews	Gene locus Smlt3243 in contig AM743169_GR.
KEGG	sml:Smlt3243.
PATRIC	23701953. VBISteMal45202_3039.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG705804.
OMA	IALICEK.
ProtClustDB	PRK00823.
Family and domain databases
HAMAP	MF_00434. Pterin_4_alpha. [Tree]
InterPro	IPR001533. Trans/pterin_deHydtase. [Graphical view]
Gene3D	G3DSA:3.30.1360.20. Trans_pterinDh. 1 hit.
KO	K01724.
PANTHER	PTHR12599. Trans_pterinDh. 1 hit.
Pfam	PF01329. Pterin_4a. 1 hit. [Graphical view]
SUPFAM	SSF55248. Trans_pterinDh. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PHS_STRMK

Accession

Primary (citable) accession number: B2FM88

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	June 10, 2008
Last modified:	January 25, 2012
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program