B2E384 (B2E384_STRPN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Dihydrofolate reductase EMBL EDT99306.1
EC=1.5.1.3 EMBL EDT99306.1

Gene names

Name:	folA EMBL EDT99306.1
ORF Names:	SPMLV016_1486 EMBL EDT99306.1

Organism

Streptococcus pneumoniae MLV-016 EMBL EDT99306.1

Taxonomic identifier

453366 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus

Protein attributes

Sequence length	168 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the dihydrofolate reductase family. RuleBase RU004474

Ontologies

Keywords
Molecular function	Oxidoreductase EMBL EDT99306.1
Gene Ontology (GO)
Biological process	glycine biosynthetic process Inferred from electronic annotation. Source: InterPro nucleotide biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	NADP binding Inferred from electronic annotation. Source: InterPro dihydrofolate reductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B2E384 [UniParc]. Last modified June 10, 2008. Version 1. Checksum: 4C3887E290B6303E	FASTA	168	19,703
	10 20 30 40 50 60 MTKKIVAIWA QDEEGVIGKE NRLPWHLPAE LQHFKETTLN HAILMGRVTF DGMGRRLLPK 70 80 90 100 110 120 RETLILTRNP EEKIDGVATF QDVQSVLDWY QAQEKNLYII GGKQIFQAFE PYLDEVIVTH 130 140 150 160 IHARVEGDTY FPEELDLSLF ETVSSKFYAK DEKNPYDFTI QYRKRKEV

References

[1]

"Genome Sequence of Streptococcus pneumoniae MLV-016." Dunning Hotopp J., Dodson R., Masignani V., Coan P., Kumar N., Covacci A., Beall B., Rappuoli R., Hollingshead S., Tettelin H. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: MLV-016 EMBL EDT99306.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	ABGH01000001 Genomic DNA. Translation: EDT99306.1.
3D structure databases
ProteinModelPortal	B2E384.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
PATRIC	28636974. VBIStrPne30809_0326.
Phylogenomic databases
OMA	QDEEGVI.
Family and domain databases
InterPro	IPR012259. DHFR. IPR024072. DHFR-like_dom. IPR017925. DHFR_CS. IPR001796. DHFR_dom. [Graphical view]
Gene3D	G3DSA:3.40.430.10. G3DSA:3.40.430.10. 1 hit.
PANTHER	PTHR11549:SF1. DHFR. 1 hit.
Pfam	PF00186. DHFR_1. 1 hit. [Graphical view]
PIRSF	PIRSF000194. DHFR. 1 hit.
PRINTS	PR00070. DHFR.
SUPFAM	SSF53597. SSF53597. 1 hit.
PROSITE	PS00075. DHFR_1. 1 hit. PS51330. DHFR_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B2E384_STRPN

Accession

Primary (citable) accession number: B2E384

Entry history

Integrated into UniProtKB/TrEMBL:	June 10, 2008
Last sequence update:	June 10, 2008
Last modified:	January 25, 2012
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)