Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

EF-hand domain (C-terminal) containing 1, isoform CRA_a

Gene

EFHC1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
EF-hand domain (C-terminal) containing 1, isoform CRA_aImported
Submitted name:
EF-hand domain containing 1Imported
Gene namesi
Name:EFHC1Imported
ORF Names:hCG_21196Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000096093.14

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA27654

PTM / Processingi

Proteomic databases

PRIDEiB2CKC5

Expressioni

Gene expression databases

BgeeiENSG00000096093
ExpressionAtlasiB2CKC5 baseline and differential

Structurei

3D structure databases

SMRiB2CKC5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini93 – 198DM10InterPro annotationAdd BLAST106
Domaini239 – 359DM10InterPro annotationAdd BLAST121
Domaini416 – 520DM10InterPro annotationAdd BLAST105
Domaini574 – 609EF-handInterPro annotationAdd BLAST36

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili556 – 576Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0043 Eukaryota
ENOG410XQCQ LUCA
HOVERGENiHBG059646
OrthoDBiEOG091G063X

Family and domain databases

CDDicd00051 EFh, 1 hit
InterProiView protein in InterPro
IPR010554 DUF1126
IPR011992 EF-hand-dom_pair
IPR002048 EF_hand_dom
IPR006602 Uncharacterised_DM10
PfamiView protein in Pfam
PF06565 DUF1126, 3 hits
SMARTiView protein in SMART
SM00676 DM10, 3 hits
SUPFAMiSSF47473 SSF47473, 1 hit
PROSITEiView protein in PROSITE
PS51336 DM10, 3 hits
PS50222 EF_HAND_2, 1 hit

Sequencei

Sequence statusi: Complete.

B2CKC5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVSNPVHGLP FLPGTSFKDS TKTAFHRSQT LSYRNGYAIV RRPTVGIGGD
60 70 80 90 100
RLQFNQLSQA ELDELASKAP VLTYGQPKQA PPADFIPAHV AFDKKVLKFD
110 120 130 140 150
AYFQEDVPMS TEEQYRIRQV NIYYYLEDDS MSVIEPVVEN SGILQGKLIK
160 170 180 190 200
RQRLAKNDRG DHYHWKDLNR GINITIYGKT FRVVDCDQFT QVFLESQGIE
210 220 230 240 250
LNPPEKMALD PYTELRKQPL RKYVTPSDFD QLKQFLTFDK QVLRFYAIWD
260 270 280 290 300
DTDSMYGECR TYIIHYYLMD DTVEIREVHE RNDGRDPFPL LMNRQRVPKV
310 320 330 340 350
LVENAKNFPQ CVLEISDQEV LEWYTAKDFI VGKSLTILGR TFFIYDCDPF
360 370 380 390 400
TRRYYKEKFG ITDLPRIDVS KREPPPVKQE LPPYNGFGLV EDSAQNCFAL
410 420 430 440 450
IPKAPKKDVI KMLVNDNKVL RYLAVLESPI PEDKDRRFVF SYFLATDMIS
460 470 480 490 500
IFEPPVRNSG IIGGKYLGRT KVVKPYSTVD NPVYYGPSDF FIGAVIEVFG
510 520 530 540 550
HRFIILDTDE YVLKYMESNA AQYSPEALAS IQNHVRKREA PAPEAESKQT
560 570 580 590 600
EKDPGVQELE ALIDTIQKQL KDHSCKDNIR EAFQIYDKEA SGYVDRDMFF
610 620 630 640
KICESLNVPV DDSLVKELIR MCSHGEGKIN YYNFVRAFSN
Length:640
Mass (Da):73,990
Last modified:May 20, 2008 - v1
Checksum:i08F9E8BFEC42FCF3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EU520261 mRNA Translation: ACB20691.1
CH471081 Genomic DNA Translation: EAX04370.1
RefSeqiNP_001165891.1, NM_001172420.1
NP_060570.2, NM_018100.3
UniGeneiHs.403171

Genome annotation databases

GeneIDi114327
KEGGihsa:114327

Similar proteinsi

Entry informationi

Entry nameiB2CKC5_HUMAN
AccessioniPrimary (citable) accession number: B2CKC5
Entry historyiIntegrated into UniProtKB/TrEMBL: May 20, 2008
Last sequence update: May 20, 2008
Last modified: May 23, 2018
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health