B2AWA2 (B2AWA2_PODAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Recommended name: DNA ligase RuleBase RU000617 EC=6.5.1.1 RuleBase RU000617
Organism	Podospora anserina (strain S / ATCC MYA-4624 / DSM 980 / FGSC 10383) (Pleurage anserina) [Complete proteome]
Taxonomic identifier	515849 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Pezizomycotina › leotiomyceta › sordariomyceta › Sordariomycetes › Sordariomycetidae › Sordariales › Lasiosphaeriaceae › Podospora › Podospora anserina

Protein attributes

Sequence length	999 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). RuleBase RU000617
Sequence similarities	Belongs to the ATP-dependent DNA ligase family. RuleBase RU004196

Ontologies

Keywords
Biological process	DNA damage DNA recombination RuleBase RU000617 DNA repair RuleBase RU000617 DNA replication RuleBase RU000617
Ligand	ATP-binding RuleBase RU000617 Nucleotide-binding
Molecular function	Ligase RuleBase RU000617
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	DNA ligation involved in DNA repair Inferred from electronic annotation. Source: InterPro DNA recombination Inferred from electronic annotation. Source: UniProtKB-KW DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW DNA binding Inferred from electronic annotation. Source: InterPro DNA ligase (ATP) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B2AWA2 [UniParc]. Last modified May 20, 2008. Version 1. Checksum: 739CA3115035B4CC	FASTA	999	112,670
	10 20 30 40 50 60 MDCKPGSSAA AGAAAAAVPG KTRFGKAKKK TGGVNYHEQR RHIIERFMSQ WRKEVGDDFY 70 80 90 100 110 120 PAMRLILPDK DRDRGVYGLK ESGIGKMLVR VMKIGRDSED GYSLLHWKLP GGGGGNQRFG 130 140 150 160 170 180 GKGQPGTAGD FAGRVLEVVG KRAMRGTPGG WTIGEVNVLL DRLAGASGEE EQLPIFEEIY 190 200 210 220 230 240 RNCCAEEVMW LVRIILKDMR VGATERTFLG LWHPDAEALF SVSSSLRRVC WELWDPETRL 250 260 270 280 290 300 EQKETGVSLM QCFQPQLAQF QMTTGFGKLV QNLGVTEEEK EFWIEEKLDG ERMQMHMKED 310 320 330 340 350 360 ETVPGGFRFA FWSRKAKDYT YLYGEGLEDD NSALTRHLKN AFHDGVRELI LDGEMITWDP 370 380 390 400 410 420 EIDKIVPFGT LKTAALDQQK NPFQNGPRPL YRVFDILLLN KKPLADYTLR DRHAALEAAV 430 440 450 460 470 480 RGEHRRLEIH PYESATTPDA IEPFLRRVVA EASEGLILKN PRSRYQLNSR NNDWIKVKPE 490 500 510 520 530 540 YMSEYGESLD CVIIGGYFGS GRRGGILSSF LCGVRVSENH VRSGAALTRE KCLSFCKVGG 550 560 570 580 590 600 GLKAEDYAEI RHHTEGKWQD WQASNPPTDY IELAGGKMQY EKPDVWIRPS ESVVMSIKAA 610 620 630 640 650 660 SIGPSDQFAM GWTLRFPRFR KLRLDKSWDE GMDASDFVLL KDKVKEEEKE RKAMEMESRK 670 680 690 700 710 720 RKPAKRLKKE LVIAGTDPNA APVEFAEGGD NIKAEPMSQV AFPPPQARRK SDNQLFQGLD 730 740 750 760 770 780 FCVLSEAVKP RKMSKPDLEK LIKEHGGRIH QQVDKGGNMI LLAEKNVVRV ASLKRAGDAD 790 800 810 820 830 840 IVKPKWVFDC LAQNNGEGYL LPFEEGHLFH ATEEMVKLAA ENTDQYGDSY VRDVTPDELR 850 860 870 880 890 900 DIIDDMRTKG GVKEEEDAFH DDRTGEFDAE HFLDQLEERG RGLEGLKSFL FRRCRVYFPV 910 920 930 940 950 960 AAKEEEEEEK SGPSSTELKA VKLQNEVKFG NGTVVGGLDD KEITHVVVVG DGEKERKELA 970 980 990 ASVRYEVSSR RHVPRIVTGR WVEDCVKEGT LVDEEGYAP

References

[1]

"The genome sequence of the model ascomycete fungus Podospora anserina." Espagne E., Lespinet O., Malagnac F., Da Silva C., Jaillon O., Porcel B.M., Couloux A., Aury J.-M., Segurens B., Poulain J., Anthouard V., Grossetete S., Khalili H., Coppin E., Dequard-Chablat M., Picard M., Contamine V., Arnaise S. , Bourdais A., Berteaux-Lecellier V., Gautheret D., de Vries R.P., Battaglia E., Coutinho P.M., Danchin E.G.J., Henrissat B., El Khoury R., Sainsard-Chanet A., Boivin A., Pinan-Lucarre B., Sellem C.H., Debuchy R., Wincker P., Weissenbach J., Silar P. Genome Biol. 9:R77.1-R77.22(2008) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: S / ATCC MYA-4624 / DSM 980 / FGSC 10383.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU633900 Genomic DNA. Translation: CAP68676.1.
RefSeq	XP_001908003.1. XM_001907968.1.
3D structure databases
ProteinModelPortal	B2AWA2.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6192594.
KEGG	pan:PODANSg5038.
Phylogenomic databases
KO	K10777.
Family and domain databases
Gene3D	2.40.50.140. 1 hit.
InterPro	IPR001357. BRCT_dom. IPR000977. DNA_ligase_ATP-dep. IPR012309. DNA_ligase_ATP-dep_C. IPR012310. DNA_ligase_ATP-dep_cent. IPR016059. DNA_ligase_ATP-dep_CS. IPR012308. DNA_ligase_ATP-dep_N. IPR021536. DNA_ligase_IV. IPR012340. NA-bd_OB-fold. [Graphical view]
Pfam	PF00533. BRCT. 1 hit. PF04679. DNA_ligase_A_C. 1 hit. PF01068. DNA_ligase_A_M. 1 hit. PF04675. DNA_ligase_A_N. 1 hit. PF11411. DNA_ligase_IV. 1 hit. [Graphical view]
SMART	SM00292. BRCT. 2 hits. [Graphical view]
SUPFAM	SSF52113. BRCT. 2 hits. SSF50249. Nucleic_acid_OB. 1 hit.
TIGRFAMs	TIGR00574. dnl1. 1 hit.
PROSITE	PS50172. BRCT. 2 hits. PS00697. DNA_LIGASE_A1. 1 hit. PS00333. DNA_LIGASE_A2. 1 hit. PS50160. DNA_LIGASE_A3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B2AWA2_PODAN

Accession

Primary (citable) accession number: B2AWA2

Entry history

Integrated into UniProtKB/TrEMBL:	May 20, 2008
Last sequence update:	May 20, 2008
Last modified:	May 1, 2013
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)