Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Trehalose-6-phosphate synthase

Gene

otsA

Organism
Cupriavidus taiwanensis (strain DSM 17343 / BCRC 17206 / CIP 107171 / LMG 19424 / R1) (Ralstonia taiwanensis (strain LMG 19424))
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor.UniRule annotation

Catalytic activityi

UDP-alpha-D-glucose + D-glucose 6-phosphate = UDP + alpha,alpha-trehalose 6-phosphate.UniRule annotation

Pathwayi: trehalose biosynthesis

This protein is involved in the pathway trehalose biosynthesis, which is part of Glycan biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway trehalose biosynthesis and in Glycan biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferaseUniRule annotationImported, Transferase

Enzyme and pathway databases

BioCyciCTAI977880:G1GJV-366-MONOMER
UniPathwayiUPA00299

Protein family/group databases

CAZyiGT20 Glycosyltransferase Family 20

Names & Taxonomyi

Protein namesi
Recommended name:
Trehalose-6-phosphate synthaseUniRule annotation (EC:2.4.1.15UniRule annotation)
Alternative name(s):
Osmoregulatory trehalose synthesis protein AUniRule annotation
UDP-glucose-glucosephosphate glucosyltransferaseUniRule annotation
Gene namesi
Name:otsAImported
Ordered Locus Names:RALTA_A0372Imported
OrganismiCupriavidus taiwanensis (strain DSM 17343 / BCRC 17206 / CIP 107171 / LMG 19424 / R1) (Ralstonia taiwanensis (strain LMG 19424))Imported
Taxonomic identifieri977880 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeCupriavidus
Proteomesi
  • UP000001692 Componenti: Chromosome 1

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi977880.RALTA_A0372

Structurei

3D structure databases

ProteinModelPortaliB2AGZ2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini18 – 458Glyco_transf_20InterPro annotationAdd BLAST441

Sequence similaritiesi

Belongs to the glycosyltransferase 20 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C1K Bacteria
COG0380 LUCA
HOGENOMiHOG000191478
KOiK00697
OMAiGYRRVNQ

Family and domain databases

CDDicd03788 GT1_TPS, 1 hit
InterProiView protein in InterPro
IPR001830 Glyco_trans_20
IPR012766 Trehalose_OtsA
PfamiView protein in Pfam
PF00982 Glyco_transf_20, 1 hit
TIGRFAMsiTIGR02400 trehalose_OtsA, 1 hit

Sequencei

Sequence statusi: Complete.

B2AGZ2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPRLVAVSNR VADPRNVAAG GLAVALSEAL RQTGGLWFGW SGKALQTAQG
60 70 80 90 100
GTPGEGDLHL QQAGNVTLAT VDLSREDHDA YYLGYSNGVL WPVFHYRLDL
110 120 130 140 150
ADFDSNFLNG YRRVNQLFAR KLAPLLQPDD IIWIHDYHLI PLASELRAIG
160 170 180 190 200
CGQKIGFFLH VPLPPPLILA AIPQHEWLMR ALFAYDLLGF QSHADVEHFS
210 220 230 240 250
RYVQAEAQAE PMGEHRYRAF HRTVRAQAFP IGIDVDEFME LGRGEEAQET
260 270 280 290 300
YEMMCAQYAR RRLLLGIDRL DYSKGLPQRL KAFYRLLAEY PENRSSATLV
310 320 330 340 350
QIAAPSRESV DAYADLRREM EQLSGSINGE FGELDWMPVR YIHRTTARKR
360 370 380 390 400
LPGLCRASRV ALVTPLRDGM NLVAKEFIAA QDPEDPGVLV LSRFAGAAEQ
410 420 430 440 450
LREALLVNPY DTRATAQAIQ QALHMPLAER HQRHQKLLER IRAQDVHWWS
460
REYLRALSET EGA
Length:463
Mass (Da):52,343
Last modified:May 20, 2008 - v1
Checksum:iA2F1D51485F9A2C2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU633749 Genomic DNA Translation: CAP63041.1
RefSeqiWP_012351706.1, NC_010528.1

Genome annotation databases

EnsemblBacteriaiCAP63041; CAP63041; RALTA_A0372
GeneIDi29760538
KEGGicti:RALTA_A0372

Similar proteinsi

Entry informationi

Entry nameiB2AGZ2_CUPTR
AccessioniPrimary (citable) accession number: B2AGZ2
Entry historyiIntegrated into UniProtKB/TrEMBL: May 20, 2008
Last sequence update: May 20, 2008
Last modified: April 25, 2018
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health