Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

B2A951

- DAPB_PODAN

UniProt

B2A951 - DAPB_PODAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Probable dipeptidyl-aminopeptidase B

Gene

DAPB

Organism
Podospora anserina (strain S / ATCC MYA-4624 / DSM 980 / FGSC 10383) (Pleurage anserina)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Type IV dipeptidyl-peptidase which removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.By similarity

Catalytic activityi

Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, from a polypeptide, preferentially when Yaa is Pro, provided Zaa is neither Pro nor hydroxyproline.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei769 – 7691Charge relay systemBy similarity
Active sitei846 – 8461Charge relay systemBy similarity
Active sitei879 – 8791Charge relay systemBy similarity

GO - Molecular functioni

  1. aminopeptidase activity Source: UniProtKB-KW
  2. serine-type peptidase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Aminopeptidase, Hydrolase, Protease, Serine protease

Protein family/group databases

MEROPSiS09.006.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable dipeptidyl-aminopeptidase B (EC:3.4.14.5)
Short name:
DPAP B
Gene namesi
Name:DAPB
Ordered Locus Names:PODANS_1_8430
OrganismiPodospora anserina (strain S / ATCC MYA-4624 / DSM 980 / FGSC 10383) (Pleurage anserina)
Taxonomic identifieri515849 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesSordariomycetidaeSordarialesLasiosphaeriaceaePodospora
ProteomesiUP000001197: Chromosome 1

Subcellular locationi

Vacuole membrane By similarity; Single-pass type II membrane protein By similarity
Note: Lysosome-like vacuoles.By similarity

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. vacuole Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Vacuole

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 927927Probable dipeptidyl-aminopeptidase BPRO_0000412159Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi365 – 3651N-linked (GlcNAc...)Sequence Analysis
Glycosylationi530 – 5301N-linked (GlcNAc...)Sequence Analysis
Glycosylationi828 – 8281N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Structurei

3D structure databases

ProteinModelPortaliB2A951.
ModBaseiSearch...
MobiDBiSearch...

Topological domain

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 108108CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini130 – 927798VacuolarSequence AnalysisAdd
BLAST

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei109 – 12921Helical; Signal-anchor for type II membrane proteinSequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase S9B family.Curated

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

KOiK01282.

Family and domain databases

Gene3Di2.140.10.30. 1 hit.
3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR001375. Peptidase_S9.
IPR002469. Peptidase_S9B.
[Graphical view]
PfamiPF00930. DPPIV_N. 1 hit.
PF00326. Peptidase_S9. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.

Sequencei

Sequence statusi: Complete.

B2A951-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAPAPGMAPY SDEPTGPFHR PEHNDESTGR MSHESESSVS TTSIVFDRIE
60 70 80 90 100
ERLAAKEGHF ELDDHDPMKE ADDDDNDLET GRFLGGRSST QEEDFPAKND
110 120 130 140 150
GMNRGMRRTL IIVAGLLISA WVVGLFFYVS HKSYKPASQI EHDPQATVVQ
160 170 180 190 200
GTGKQVTLDQ VMGSYWRAES HSISWIESPD GEDGLLLLKD GPGKDFLVVE
210 220 230 240 250
DVRTQNSAGV NAAVDVASSR TLIKERHFDF GGQTHTPGRV WPSKDLKKVL
260 270 280 290 300
IATNLEANWR HSFYASYWVF DVDMQIAEPL IPGEPNVRVQ LAQWSPTSDA
310 320 330 340 350
IAYVRDNNLF LRSLKHDKVV QITKDGGAEV FNGVPDWVYE EEVFSGNSAT
360 370 380 390 400
WWSEDGNYIA YLRTNETGVP EYPVQYFLSR PSGTEPAPGE ESYPEVRQIK
410 420 430 440 450
YPKAGAHNPV VNLKFYDVAR DESFTVEISG RFADDDRLIT EVVWAGGQVI
460 470 480 490 500
VKETNRVSDV LRVVLVDVAA RTGKAVRELD VKAIDGGWFE ITHKTKYIPA
510 520 530 540 550
DPSKGREQDG YIDMVIHDDN DHLAYFTPLN NSEPIMLTSG HWEVVDAPST
560 570 580 590 600
VDLDNNIVYF VATKESSIQR HVYQVDLSGN NLKAVTDTGS EGYYDISFSA
610 620 630 640 650
GTGYALLSYR GPNIPWQKVI STPANAHKYE HMVEENKELA KSAREYELPI
660 670 680 690 700
KIYGTIKVDG VELNYVERRP PHFDKNKKYP VLFQQYSGPG SQSVNKRFTV
710 720 730 740 750
DYQSYVAAGL GYVCVTVDGR GTGFIGRKNR VIIRGDLGKW EAHDQIAAAK
760 770 780 790 800
IWASKSYVDE ERLAIWGWSF GGFNTLKTLE QDGGRTFKYG MAVAPVTDWR
810 820 830 840 850
FYDSIYTERY MLTPQTNGHG YDTSAINNVT ALKQSVRFLM MHGVADDNVH
860 870 880 890 900
MQNSLTLLDK LNMVGVENYD VHVFPDSDHG IYFHNANRIV YDKLTNWLIN
910 920
AFNGEWIKVA NAKPQKKRSI QPILPIL
Length:927
Mass (Da):104,169
Last modified:May 20, 2008 - v1
Checksum:i288D2A5A7DD9AC52
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU633438 Genomic DNA. Translation: CAP60552.1.
RefSeqiXP_001913070.1. XM_001913035.1.

Genome annotation databases

GeneIDi6197654.
KEGGipan:PODANSg10119.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU633438 Genomic DNA. Translation: CAP60552.1 .
RefSeqi XP_001913070.1. XM_001913035.1.

3D structure databases

ProteinModelPortali B2A951.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

MEROPSi S09.006.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 6197654.
KEGGi pan:PODANSg10119.

Phylogenomic databases

KOi K01282.

Family and domain databases

Gene3Di 2.140.10.30. 1 hit.
3.40.50.1820. 1 hit.
InterProi IPR029058. AB_hydrolase.
IPR001375. Peptidase_S9.
IPR002469. Peptidase_S9B.
[Graphical view ]
Pfami PF00930. DPPIV_N. 1 hit.
PF00326. Peptidase_S9. 1 hit.
[Graphical view ]
SUPFAMi SSF53474. SSF53474. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: S / ATCC MYA-4624 / DSM 980 / FGSC 10383.

Entry informationi

Entry nameiDAPB_PODAN
AccessioniPrimary (citable) accession number: B2A951
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 27, 2011
Last sequence update: May 20, 2008
Last modified: October 29, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Peptidase families
    Classification of peptidase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3