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B2A6E4 (GLGA_NATTJ) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glycogen synthase

EC=2.4.1.21
Alternative name(s):
Starch [bacterial glycogen] synthase
Gene names
Name:glgA
Ordered Locus Names:Nther_0559
OrganismNatranaerobius thermophilus (strain ATCC BAA-1301 / DSM 18059 / JW/NM-WN-LF) [Complete proteome] [HAMAP]
Taxonomic identifier457570 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaNatranaerobialesNatranaerobiaceaeNatranaerobius

Protein attributes

Sequence length496 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Synthesizes alpha-1,4-glucan chains using ADP-glucose By similarity. HAMAP-Rule MF_00484

Catalytic activity

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1). HAMAP-Rule MF_00484

Pathway

Glycan biosynthesis; glycogen biosynthesis. HAMAP-Rule MF_00484

Sequence similarities

Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.

Ontologies

Keywords
   Biological processGlycogen biosynthesis
   Molecular functionGlycosyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycogen biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionstarch synthase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 496496Glycogen synthase HAMAP-Rule MF_00484
PRO_1000126086

Sites

Binding site151ADP-glucose By similarity

Sequences

Sequence LengthMass (Da)Tools
B2A6E4 [UniParc].

Last modified May 20, 2008. Version 1.
Checksum: 38B72975E91B310F

FASTA49657,308
        10         20         30         40         50         60 
MKVLVATAEA SPFAKRGGLG DVLGALPIAI KKQSEIDIRV VLPGYSAIPS QFKSEFQPID 

        70         80         90        100        110        120 
SIIIPLGWRA QKSRVSSYNF RNVTFYFIEN DYYFNREDIY GYFDEAEQFG FFSKAILDIM 

       130        140        150        160        170        180 
PLLDFYPDII HLNDWHTAMV SPLLKYKYAH KTNYNQMKTI LTIHNLKYQG IFTPHVLEDF 

       190        200        210        220        230        240 
FDLHDHKLQH DPEYLEYHGQ ISFLKGGLIF SDAITTVSPT YAKEIQSPEL GMGVDGLLHK 

       250        260        270        280        290        300 
RRDDLYGILN GIDYQDYNPK TDVNIYRNYN LPDEGKTNEK LINKLRLQED LRLPVSSRVP 

       310        320        330        340        350        360 
LIAFINRLVK QKGLDLITYV LPELLESEEV QFVFLGTGDP HYEQYLSYLA EKHQNLSAQI 

       370        380        390        400        410        420 
KFDEGLARKI YAASDLFLMP SLFEPCGIGQ QIAIRYGSVP IVRKVGGLHD TVYPSISEEG 

       430        440        450        460        470        480 
TRGIGFTFES FNAHEMLFTI KEAIQYYHQK AFWQEIINNL TTIDFSWEKS ACEYIELYHK 

       490 
LIHRNTNSTR KESYLK 

« Hide

References

[1]"Complete sequence of chromosome of Natranaerobius thermophilus JW/NM-WN-LF."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L. expand/collapse author list , Kyrpides N., Lykidis A., Mesbah N.M., Wiegel J.
Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-1301 / DSM 18059 / JW/NM-WN-LF.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001034 Genomic DNA. Translation: ACB84155.1.
RefSeqYP_001916743.1. NC_010718.1.

3D structure databases

ProteinModelPortalB2A6E4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING457570.Nther_0559.

Protein family/group databases

CAZyGT5. Glycosyltransferase Family 5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACB84155; ACB84155; Nther_0559.
GeneID6314669.
KEGGnth:Nther_0559.
PATRIC22669740. VBINatThe92436_0580.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0297.
HOGENOMHOG000294940.
KOK00703.
OMAMWQLASR.
OrthoDBEOG6JTC6Z.

Enzyme and pathway databases

BioCycNTHE457570:GHRL-585-MONOMER.
UniPathwayUPA00164.

Family and domain databases

HAMAPMF_00484. Glycogen_synth.
InterProIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsTIGR02095. glgA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLGA_NATTJ
AccessionPrimary (citable) accession number: B2A6E4
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: May 20, 2008
Last modified: May 14, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways