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Protein

Glycogen synthase

Gene

glgA

Organism
Natranaerobius thermophilus (strain ATCC BAA-1301 / DSM 18059 / JW/NM-WN-LF)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Synthesizes alpha-1,4-glucan chains using ADP-glucose.UniRule annotation

Catalytic activityi

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1).UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei15 – 151ADP-glucoseUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Glycogen biosynthesis

Enzyme and pathway databases

BioCyciNTHE457570:GHRL-585-MONOMER.
UniPathwayiUPA00164.

Protein family/group databases

CAZyiGT5. Glycosyltransferase Family 5.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycogen synthaseUniRule annotation (EC:2.4.1.21UniRule annotation)
Alternative name(s):
Starch [bacterial glycogen] synthaseUniRule annotation
Gene namesi
Name:glgAUniRule annotation
Ordered Locus Names:Nther_0559
OrganismiNatranaerobius thermophilus (strain ATCC BAA-1301 / DSM 18059 / JW/NM-WN-LF)
Taxonomic identifieri457570 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaNatranaerobialesNatranaerobiaceaeNatranaerobius
ProteomesiUP000001683 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 496496Glycogen synthasePRO_1000126086Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi457570.Nther_0559.

Structurei

3D structure databases

ProteinModelPortaliB2A6E4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0297.
HOGENOMiHOG000294940.
KOiK00703.
OMAiLTCAYLE.
OrthoDBiEOG6JTC6Z.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.

Sequencei

Sequence statusi: Complete.

B2A6E4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKVLVATAEA SPFAKRGGLG DVLGALPIAI KKQSEIDIRV VLPGYSAIPS
60 70 80 90 100
QFKSEFQPID SIIIPLGWRA QKSRVSSYNF RNVTFYFIEN DYYFNREDIY
110 120 130 140 150
GYFDEAEQFG FFSKAILDIM PLLDFYPDII HLNDWHTAMV SPLLKYKYAH
160 170 180 190 200
KTNYNQMKTI LTIHNLKYQG IFTPHVLEDF FDLHDHKLQH DPEYLEYHGQ
210 220 230 240 250
ISFLKGGLIF SDAITTVSPT YAKEIQSPEL GMGVDGLLHK RRDDLYGILN
260 270 280 290 300
GIDYQDYNPK TDVNIYRNYN LPDEGKTNEK LINKLRLQED LRLPVSSRVP
310 320 330 340 350
LIAFINRLVK QKGLDLITYV LPELLESEEV QFVFLGTGDP HYEQYLSYLA
360 370 380 390 400
EKHQNLSAQI KFDEGLARKI YAASDLFLMP SLFEPCGIGQ QIAIRYGSVP
410 420 430 440 450
IVRKVGGLHD TVYPSISEEG TRGIGFTFES FNAHEMLFTI KEAIQYYHQK
460 470 480 490
AFWQEIINNL TTIDFSWEKS ACEYIELYHK LIHRNTNSTR KESYLK
Length:496
Mass (Da):57,308
Last modified:May 20, 2008 - v1
Checksum:i38B72975E91B310F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001034 Genomic DNA. Translation: ACB84155.1.
RefSeqiWP_012447041.1. NC_010718.1.
YP_001916743.1. NC_010718.1.

Genome annotation databases

EnsemblBacteriaiACB84155; ACB84155; Nther_0559.
KEGGinth:Nther_0559.
PATRICi22669740. VBINatThe92436_0580.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001034 Genomic DNA. Translation: ACB84155.1.
RefSeqiWP_012447041.1. NC_010718.1.
YP_001916743.1. NC_010718.1.

3D structure databases

ProteinModelPortaliB2A6E4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi457570.Nther_0559.

Protein family/group databases

CAZyiGT5. Glycosyltransferase Family 5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACB84155; ACB84155; Nther_0559.
KEGGinth:Nther_0559.
PATRICi22669740. VBINatThe92436_0580.

Phylogenomic databases

eggNOGiCOG0297.
HOGENOMiHOG000294940.
KOiK00703.
OMAiLTCAYLE.
OrthoDBiEOG6JTC6Z.

Enzyme and pathway databases

UniPathwayiUPA00164.
BioCyciNTHE457570:GHRL-585-MONOMER.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of chromosome of Natranaerobius thermophilus JW/NM-WN-LF."
    US DOE Joint Genome Institute
    Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L.
    , Kyrpides N., Lykidis A., Mesbah N.M., Wiegel J.
    Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-1301 / DSM 18059 / JW/NM-WN-LF.

Entry informationi

Entry nameiGLGA_NATTJ
AccessioniPrimary (citable) accession number: B2A6E4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: May 20, 2008
Last modified: April 29, 2015
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.