ID   B2A3Q1_NATTJ            Unreviewed;       833 AA.
AC   B2A3Q1;
DT   20-MAY-2008, integrated into UniProtKB/TrEMBL.
DT   20-MAY-2008, sequence version 1.
DT   27-MAR-2024, entry version 79.
DE   SubName: Full=Stage II sporulation protein E, protein serine/threonine phosphatase {ECO:0000313|EMBL:ACB83677.1};
DE            EC=3.1.3.16 {ECO:0000313|EMBL:ACB83677.1};
GN   OrderedLocusNames=Nther_0078 {ECO:0000313|EMBL:ACB83677.1};
OS   Natranaerobius thermophilus (strain ATCC BAA-1301 / DSM 18059 /
OS   JW/NM-WN-LF).
OC   Bacteria; Bacillota; Clostridia; Natranaerobiales; Natranaerobiaceae;
OC   Natranaerobius.
OX   NCBI_TaxID=457570 {ECO:0000313|EMBL:ACB83677.1, ECO:0000313|Proteomes:UP000001683};
RN   [1] {ECO:0000313|EMBL:ACB83677.1, ECO:0000313|Proteomes:UP000001683}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1301 / DSM 18059 / JW/NM-WN-LF
RC   {ECO:0000313|Proteomes:UP000001683};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C.,
RA   Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L.,
RA   Kyrpides N., Lykidis A., Mesbah N.M., Wiegel J.;
RT   "Complete sequence of chromosome of Natranaerobius thermophilus JW/NM-WN-
RT   LF.";
RL   Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ACB83677.1, ECO:0000313|Proteomes:UP000001683}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1301 / DSM 18059 / JW/NM-WN-LF
RC   {ECO:0000313|Proteomes:UP000001683};
RX   PubMed=21642468; DOI=10.1128/JB.05157-11;
RA   Zhao B., Mesbah N.M., Dalin E., Goodwin L., Nolan M., Pitluck S.,
RA   Chertkov O., Brettin T.S., Han J., Larimer F.W., Land M.L., Hauser L.,
RA   Kyrpides N., Wiegel J.;
RT   "Complete genome sequence of the anaerobic, halophilic alkalithermophile
RT   Natranaerobius thermophilus JW/NM-WN-LF.";
RL   J. Bacteriol. 193:4023-4024(2011).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP001034; ACB83677.1; -; Genomic_DNA.
DR   RefSeq; WP_012446568.1; NC_010718.1.
DR   AlphaFoldDB; B2A3Q1; -.
DR   STRING; 457570.Nther_0078; -.
DR   KEGG; nth:Nther_0078; -.
DR   eggNOG; COG0697; Bacteria.
DR   eggNOG; COG2208; Bacteria.
DR   HOGENOM; CLU_017349_0_0_9; -.
DR   InParanoid; B2A3Q1; -.
DR   OrthoDB; 9763774at2; -.
DR   Proteomes; UP000001683; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0017018; F:myosin phosphatase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   InterPro; IPR014221; SpoII_E.
DR   InterPro; IPR045768; SpoIIE_N.
DR   NCBIfam; TIGR02865; spore_II_E; 1.
DR   PANTHER; PTHR43156:SF12; STAGE II SPORULATION PROTEIN E; 1.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   Pfam; PF19732; SpoIIE_N; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:ACB83677.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001683};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        45..67
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        95..127
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        139..156
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        162..183
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        204..222
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        228..245
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        252..283
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        289..307
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        319..335
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          601..810
FT                   /note="PPM-type phosphatase"
FT                   /evidence="ECO:0000259|SMART:SM00331"
SQ   SEQUENCE   833 AA;  93002 MW;  7224E8B76ADA7CB9 CRC64;
     MAYETEYIKT YERTYKQAYQ PLDTSKSATP RTKLLVTFWE KFRELFIKLF NGVTSLSTLY
     LLTGFLLGRA EVRGGLIPLV LAYLLALRLE KASYFSAAFI GSLIGIQLTH GIEGTVTVII
     PAMIYLLWER RSLGNKPKIG TVIFVASFMV TSWFYGGLPG SFPFNLLPLA IEGGLLVIFA
     VLLMPGLQFI ESKRKTDNIE KEEIVSIILL ASMAFMGLQG IMIGPYSIPR LVSLLAVLIV
     GYRYGGGQGA AAGAILGTIT SFYSLSQISI GALTLSGLLA GIFKDFGKLS STFAFIFSSG
     LVVFYLGEPF VMLHFLQEIL IISVIFLVIP ERFFYKITPS PISHGSKMVS DRKMDQIINH
     KFYEFASLFS DMAKVFEPNS NEQDYHDSSE IEDFVQTVVN QVCGGCSKVS YCWEKNFFVT
     YKNFLNVISK VDSGKKLHRD ELPEYLQESC IRPSLLLENA GSVFDDYQLE HNKAKSSAAE
     NKKLLSEQMF ALSELFNKMA KFKVVDSSNN RELEQEIRSA IENKNFVCEE ICVTGKVQED
     LTIELIINCS GTKQEDIKEI STLVSEVVGE KLSPVTWDLY REDSKINNHY FIRLRAEQQL
     QVITGCIQIN KEGEPLSGDT YMSRELSTGE HLLLLSDGMG SGSKANEESE ATVNLITKLL
     NYGYDKQMVI RSVNSLLATI NRVDSFATVD MALIDLYTGI GEFCKAGAVS SFISTAEGVE
     KVEASSLPAG IIESVEPKKM TYSLKPGDYL YMVSDGVFDM GDGEKWFEKA ISNLKSKDPQ
     EMAEELLEKV KRRYSYGDFP DDVTILIAKI TSNSKESELD SQTMGLDIWE KIN
//