B2A258 (B2A258_NATTJ) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Chorismate synthase HAMAP MF_00300
EC=4.2.3.5 HAMAP MF_00300

Alternative name(s):
5-enolpyruvylshikimate-3-phosphate phospholyase HAMAP MF_00300

Gene names

Name:	aroC HAMAP MF_00300
Ordered Locus Names:	Nther_1280

Organism

Natranaerobius thermophilus (strain ATCC BAA-1301 / DSM 18059 / JW/NM-WN-LF) [Complete proteome] [HAMAP]

Taxonomic identifier

457570 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Natranaerobiales › Natranaerobiaceae › Natranaerobius

Protein attributes

Sequence length	408 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300
Cofactor	Reduced flavin By similarity. HAMAP MF_00300
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300
Subunit structure	Homotetramer By similarity. HAMAP MF_00300
Sequence similarities	Belongs to the chorismate synthase family. HAMAP MF_00300

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis HAMAP MF_00300
Molecular function	Lyase HAMAP MF_00300 EMBL ACB84863.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	chorismate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B2A258 [UniParc]. Last modified May 20, 2008. Version 1. Checksum: E4A6A80DC0840BAF	FASTA	408	44,885
	10 20 30 40 50 60 MSLNFLTAGE SHGPALVGIL EGFWSNFEID ESKINSELAR RQSGYGRGGR MKIEGDTVNF 70 80 90 100 110 120 LGGVRQGVTT GAPIAFQIFN KDYQNWKDEM NPSKIDSEES STKQSESQSK FNTQVTKPRP 130 140 150 160 170 180 GHADLAGALK YDQSDIRNIL ERSSARETAM RTAVGSLCKQ LLQDLNIKII SHVTRIGSIS 190 200 210 220 230 240 LSQELTGVTH TNNFSNMKEL ISNLERSQLN CIDPKTEQKM IEEIDSTRLQ GDTLGGEFEV 250 260 270 280 290 300 IVENLPPGLG SHVHYHRKLD GLLAGALMGL QGIKGVEIGA GFQTATLPGS QIHDEIFYSQ 310 320 330 340 350 360 DRGYYRDQNN AGGVEGGISN GEPVIVRGAM KPIPTLSKPL KSVDIHTKEA FDAQIERSDC 370 380 390 400 CAVPSAAIVA EHIIAYELAK VVKEKFGSDS IDELRRNYQA YFEYLDTR

References

[1]

"Complete sequence of chromosome of Natranaerobius thermophilus JW/NM-WN-LF." Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L. , Kyrpides N., Lykidis A., Mesbah N.M., Wiegel J. Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-1301 / DSM 18059 / JW/NM-WN-LF.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001034 Genomic DNA. Translation: ACB84863.1.
RefSeq	YP_001917451.1. NC_010718.1.
3D structure databases
ProteinModelPortal	B2A258.
ModBase	Search...
Protein-protein interaction databases
STRING	B2A258.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6315526.
GenomeReviews	Gene locus Nther_1280 in contig CP001034_GR.
KEGG	nth:Nther_1280.
PATRIC	22671226. VBINatThe92436_1315.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG292336.
OMA	MLRWLTA.
ProtClustDB	PRK05382.
Family and domain databases
HAMAP	MF_00300. Chorismate_synth. [Tree]
InterPro	IPR000453. Chorismate_synth. IPR020541. Chorismate_synthase_CS. [Graphical view]
KO	K01736.
PANTHER	PTHR21085. Chorismate_synth. 1 hit.
Pfam	PF01264. Chorismate_synt. 1 hit. [Graphical view]
PIRSF	PIRSF001456. Chorismate_synth. 1 hit.
SUPFAM	SSF103263. Chorismate_synth. 1 hit.
TIGRFAMs	TIGR00033. AroC. 1 hit.
PROSITE	PS00788. CHORISMATE_SYNTHASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B2A258_NATTJ

Accession

Primary (citable) accession number: B2A258

Entry history

Integrated into UniProtKB/TrEMBL:	May 20, 2008
Last sequence update:	May 20, 2008
Last modified:	January 25, 2012
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)