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B1ZY55 (B1ZY55_OPITP) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
L-threonine 3-dehydrogenase 2 HAMAP MF_00627
EC=1.1.1.103 HAMAP MF_00627
Gene names
Name:tdh2 HAMAP MF_00627
Ordered Locus Names:Oter_2923
OrganismOpitutus terrae (strain DSM 11246 / PB90-1) [Complete proteome] [HAMAP]
Taxonomic identifier452637 [NCBI]
Taxonomic lineageBacteria › Verrucomicrobia › Opitutae › Opitutales › Opitutaceae › Opitutus

Protein attributes

Sequence length349 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-threonine + NAD+ = L-2-amino-3-oxobutanoate + NADH. HAMAP MF_00627 SAAS SAAS002328

Cofactor

Binds 2 zinc ions per subunit By similarity. HAMAP MF_00627 SAAS SAAS002328

Pathway

Amino-acid degradation; L-threonine degradation via oxydo-reductase pathway; glycine from L-threonine: step 1/2. HAMAP MF_00627 SAAS SAAS002328

Subunit structure

Homotetramer By similarity. HAMAP MF_00627

Subcellular location

Cytoplasm By similarity HAMAP MF_00627 SAAS SAAS002328.

Sequence similarities

Belongs to the zinc-containing alcohol dehydrogenase family. HAMAP MF_00627 RuleBase RU000468

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding441Zinc 1; catalytic By similarity HAMAP MF_00627
Metal binding691Zinc 1; catalytic By similarity HAMAP MF_00627
Metal binding991Zinc 2 By similarity HAMAP MF_00627
Metal binding1021Zinc 2 By similarity HAMAP MF_00627
Metal binding1051Zinc 2 By similarity HAMAP MF_00627
Metal binding1131Zinc 2 By similarity HAMAP MF_00627
Metal binding1541Zinc 1; catalytic By similarity HAMAP MF_00627

Sequences

Sequence LengthMass (Da)Tools
B1ZY55 [UniParc].

Last modified May 20, 2008. Version 1.
Checksum: 3F81561B25CB5FB6

FASTA34937,790
        10         20         30         40         50         60 
MHLPTTMQAI AKLKPGPGLN LIEVPVPVPG INDVLIRIKR TSICGTDIHI YNWDAWAAKT 

        70         80         90        100        110        120 
IPAPMVIGHE FVGEVAAVGS NVTTFQIGEL VDGEGHIVCG VCRNCLAGRR HLCKDTKGVG 

       130        140        150        160        170        180 
VNRPGAFAEY LCLPSSNAVK VDPTISLDVL SCFDPLGNAT HTALQYDLVG EDVLITGAGP 

       190        200        210        220        230        240 
IGCMAAAIAQ QAGARKVVVT DVNPDRLALA QRMGATRVVD VSKEKLPDVQ HEIGMKEGFD 

       250        260        270        280        290        300 
VGLEMSGNPR ALNDMIDNMA HGGRIALLGI MPERAAVDWN KVVFNMLTIR GIYGREIYAT 

       310        320        330        340 
WYKMQSLIQR GLDITPVITH RMPFTDFERG FELMRSGKSG KIVLNWEVA

« Hide

References

[1]"Complete sequence of Opitutus terrae PB90-1."
Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Pitluck S., Goltsman E., Clum A., Sun H., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Smidt H., Richardson P.
Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 11246 / PB90-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001032 Genomic DNA. Translation: ACB76204.1.
RefSeqYP_001819804.1. NC_010571.1.

3D structure databases

ProteinModelPortalB1ZY55.
ModBaseSearch...

Protein-protein interaction databases

STRINGB1ZY55.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6207125.
GenomeReviewsGene locus Oter_2923 in contig CP001032_GR.
KEGGote:Oter_2923.
PATRIC22817535. VBIOpiTer17422_3036.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG753318.
OMAGRCRNCL.
ProtClustDBPRK05396.

Family and domain databases

HAMAPMF_00627. Thr_dehydrog.
[Tree]
InterProIPR013149. ADH_C.
IPR013154. ADH_GroES-like.
IPR002085. ADH_SF_Zn-type.
IPR002328. ADH_Zn_CS.
IPR011032. GroES-like.
IPR004627. L-Threonine_3-DHase.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KOK00060.
PANTHERPTHR11695. ADH_Sf_Zn. 1 hit.
PfamPF08240. ADH_N. 1 hit.
PF00107. ADH_zinc_N. 1 hit.
[Graphical view]
SUPFAMSSF50129. GroES_like. 1 hit.
TIGRFAMsTIGR00692. Tdh. 1 hit.
PROSITEPS00059. ADH_ZINC. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB1ZY55_OPITP
AccessionPrimary (citable) accession number: B1ZY55
Entry history
Integrated into UniProtKB/TrEMBL: May 20, 2008
Last sequence update: May 20, 2008
Last modified: December 14, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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