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Protein

tRNA pseudouridine synthase B

Gene

truB

Organism
Opitutus terrae (strain DSM 11246 / PB90-1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei45 – 451NucleophileUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

tRNA processing

Enzyme and pathway databases

BioCyciOTER452637:GHBR-2873-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
Alternative name(s):
tRNA pseudouridine(55) synthaseUniRule annotation
Short name:
Psi55 synthaseUniRule annotation
tRNA pseudouridylate synthaseUniRule annotation
tRNA-uridine isomeraseUniRule annotation
Gene namesi
Name:truBUniRule annotation
Ordered Locus Names:Oter_2817
OrganismiOpitutus terrae (strain DSM 11246 / PB90-1)
Taxonomic identifieri452637 [NCBI]
Taxonomic lineageiBacteriaVerrucomicrobiaOpitutaeOpitutalesOpitutaceaeOpitutus
Proteomesi
  • UP000007013 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 241241tRNA pseudouridine synthase BPRO_1000213506Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi452637.Oter_2817.

Structurei

3D structure databases

ProteinModelPortaliB1ZX46.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D0T. Bacteria.
COG0130. LUCA.
HOGENOMiHOG000231223.
KOiK03177.
OMAiKWLFNAQ.
OrthoDBiEOG6358D3.

Family and domain databases

HAMAPiMF_01080. TruB_bact.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR002501. PsdUridine_synth_N.
IPR014780. tRNA_psdUridine_synth_TruB.
IPR032819. TruB_C.
[Graphical view]
PANTHERiPTHR13767. PTHR13767. 1 hit.
PfamiPF16198. TruB_C_2. 1 hit.
PF01509. TruB_N. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00431. TruB. 1 hit.

Sequencei

Sequence statusi: Complete.

B1ZX46-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIQPRKELDG VLLVDKPTAH TSHDVVARLR RKLNMKRIGH AGTLDPMATG
60 70 80 90 100
LMILLIGKAT TISQYLTSLD KEYEGTIELG KVTDSQDADG EVLSTLPVPP
110 120 130 140 150
FTEAEIRAAM AGFMGDQYQT PPMYSAIKVD GVPLYKTARK GGEVEREPRF
160 170 180 190 200
IRVSSFELTR FALPQFDFRL RCTKGTYVRT IAHDLGQRLG CGAHLAALRR
210 220 230 240
TATDKFKLAD ALTLDAIEAL PLPEIEKRLI PVYQAAPSIV G
Length:241
Mass (Da):26,563
Last modified:May 20, 2008 - v1
Checksum:i647B9B9EB20B14CE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001032 Genomic DNA. Translation: ACB76098.1.
RefSeqiWP_012375633.1. NC_010571.1.

Genome annotation databases

EnsemblBacteriaiACB76098; ACB76098; Oter_2817.
KEGGiote:Oter_2817.
PATRICi22817309. VBIOpiTer17422_2925.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001032 Genomic DNA. Translation: ACB76098.1.
RefSeqiWP_012375633.1. NC_010571.1.

3D structure databases

ProteinModelPortaliB1ZX46.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi452637.Oter_2817.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACB76098; ACB76098; Oter_2817.
KEGGiote:Oter_2817.
PATRICi22817309. VBIOpiTer17422_2925.

Phylogenomic databases

eggNOGiENOG4105D0T. Bacteria.
COG0130. LUCA.
HOGENOMiHOG000231223.
KOiK03177.
OMAiKWLFNAQ.
OrthoDBiEOG6358D3.

Enzyme and pathway databases

BioCyciOTER452637:GHBR-2873-MONOMER.

Family and domain databases

HAMAPiMF_01080. TruB_bact.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR002501. PsdUridine_synth_N.
IPR014780. tRNA_psdUridine_synth_TruB.
IPR032819. TruB_C.
[Graphical view]
PANTHERiPTHR13767. PTHR13767. 1 hit.
PfamiPF16198. TruB_C_2. 1 hit.
PF01509. TruB_N. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00431. TruB. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 11246 / PB90-1.

Entry informationi

Entry nameiTRUB_OPITP
AccessioniPrimary (citable) accession number: B1ZX46
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: May 20, 2008
Last modified: January 20, 2016
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.