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B1ZUV7

- SYE_OPITP

UniProt

B1ZUV7 - SYE_OPITP

Protein

Glutamate--tRNA ligase

Gene

gltX

Organism
Opitutus terrae (strain DSM 11246 / PB90-1)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 44 (01 Oct 2014)
      Sequence version 1 (20 May 2008)
      Previous versions | rss
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    Functioni

    Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).UniRule annotation

    Catalytic activityi

    ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu).UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei228 – 2281ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. glutamate-tRNA ligase activity Source: UniProtKB-HAMAP
    3. tRNA binding Source: InterPro

    GO - Biological processi

    1. glutamyl-tRNA aminoacylation Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Aminoacyl-tRNA synthetase, Ligase

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciOTER452637:GHBR-2699-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutamate--tRNA ligaseUniRule annotation (EC:6.1.1.17UniRule annotation)
    Alternative name(s):
    Glutamyl-tRNA synthetaseUniRule annotation
    Short name:
    GluRSUniRule annotation
    Gene namesi
    Name:gltXUniRule annotation
    Ordered Locus Names:Oter_2646
    OrganismiOpitutus terrae (strain DSM 11246 / PB90-1)
    Taxonomic identifieri452637 [NCBI]
    Taxonomic lineageiBacteriaVerrucomicrobiaOpitutaeOpitutalesOpitutaceaeOpitutus
    ProteomesiUP000007013: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 460460Glutamate--tRNA ligasePRO_0000367724Add
    BLAST

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi452637.Oter_2646.

    Structurei

    3D structure databases

    ProteinModelPortaliB1ZUV7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi10 – 2011"HIGH" regionAdd
    BLAST
    Motifi225 – 2295"KMSKS" region

    Sequence similaritiesi

    Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0008.
    HOGENOMiHOG000252720.
    KOiK01885.
    OMAiKRDANIM.
    OrthoDBiEOG6DRPF7.

    Family and domain databases

    Gene3Di1.10.10.350. 1 hit.
    1.10.1160.10. 1 hit.
    3.40.50.620. 2 hits.
    HAMAPiMF_00022_B. Glu_tRNA_synth_B.
    InterProiIPR008925. aa-tRNA-synth_I_codon-bd.
    IPR020751. aa-tRNA-synth_I_codon-bd_sub2.
    IPR004527. Glu-tRNA-ligase_bac/mito.
    IPR000924. Glu/Gln-tRNA-synth.
    IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
    IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
    IPR014729. Rossmann-like_a/b/a_fold.
    [Graphical view]
    PANTHERiPTHR10119. PTHR10119. 1 hit.
    PfamiPF00749. tRNA-synt_1c. 2 hits.
    [Graphical view]
    PRINTSiPR00987. TRNASYNTHGLU.
    SUPFAMiSSF48163. SSF48163. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B1ZUV7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAHVRVRFAP SPTGFFHIGS ARTALFNWLY ARHTGGTFVL RIEDTDKERN    50
    SEAFLNVIYD SLRWLGMEWD EGPGKGGEFG PYRQSERDAV YREYLAKLTA 100
    AGRTYEKDGA IWFKLLGERY EVFDEHRKKT VTKVKTAPTV IEDRIRGRVE 150
    RVEDEDFVIF RSDGNPVFHF VNVVDDIAMQ ITHVIRGEDH LSNTSKHVEL 200
    FKAFGAPVPQ FAHIPLILKQ NGPGKMSKRD QGALIEEYQR RGYLSEALVN 250
    FLSLLGWNPG DDREKMPIAE IIRLFDLPGV NQSNARFDDK KLAHMNMAYL 300
    LELPADTFVQ KARAFFESLG DNATAKAALA AEPAFFREVM LLSQPKIKGF 350
    EELPAYTAYF FTDEFATDAK VRDKVMGKGD PKARLRELIE ALPGFDFSND 400
    AAVEEGIKVL ATKNALGFGD YQSVARLGVS GTNVGPSITG MFRVLGRERV 450
    RARLERLLNA 460
    Length:460
    Mass (Da):51,927
    Last modified:May 20, 2008 - v1
    Checksum:iC1F34FE57EB80CBA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001032 Genomic DNA. Translation: ACB75927.1.
    RefSeqiYP_001819527.1. NC_010571.1.

    Genome annotation databases

    EnsemblBacteriaiACB75927; ACB75927; Oter_2646.
    GeneIDi6206933.
    KEGGiote:Oter_2646.
    PATRICi22816961. VBIOpiTer17422_2753.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001032 Genomic DNA. Translation: ACB75927.1 .
    RefSeqi YP_001819527.1. NC_010571.1.

    3D structure databases

    ProteinModelPortali B1ZUV7.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 452637.Oter_2646.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACB75927 ; ACB75927 ; Oter_2646 .
    GeneIDi 6206933.
    KEGGi ote:Oter_2646.
    PATRICi 22816961. VBIOpiTer17422_2753.

    Phylogenomic databases

    eggNOGi COG0008.
    HOGENOMi HOG000252720.
    KOi K01885.
    OMAi KRDANIM.
    OrthoDBi EOG6DRPF7.

    Enzyme and pathway databases

    BioCyci OTER452637:GHBR-2699-MONOMER.

    Family and domain databases

    Gene3Di 1.10.10.350. 1 hit.
    1.10.1160.10. 1 hit.
    3.40.50.620. 2 hits.
    HAMAPi MF_00022_B. Glu_tRNA_synth_B.
    InterProi IPR008925. aa-tRNA-synth_I_codon-bd.
    IPR020751. aa-tRNA-synth_I_codon-bd_sub2.
    IPR004527. Glu-tRNA-ligase_bac/mito.
    IPR000924. Glu/Gln-tRNA-synth.
    IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
    IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
    IPR014729. Rossmann-like_a/b/a_fold.
    [Graphical view ]
    PANTHERi PTHR10119. PTHR10119. 1 hit.
    Pfami PF00749. tRNA-synt_1c. 2 hits.
    [Graphical view ]
    PRINTSi PR00987. TRNASYNTHGLU.
    SUPFAMi SSF48163. SSF48163. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 11246 / PB90-1.

    Entry informationi

    Entry nameiSYE_OPITP
    AccessioniPrimary (citable) accession number: B1ZUV7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 24, 2009
    Last sequence update: May 20, 2008
    Last modified: October 1, 2014
    This is version 44 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Aminoacyl-tRNA synthetases
      List of aminoacyl-tRNA synthetase entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3