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B1ZUU9

- B1ZUU9_OPITP

UniProt

B1ZUU9 - B1ZUU9_OPITP

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Protein

D-alanine--D-alanine ligase

Gene

ddl

Organism
Opitutus terrae (strain DSM 11246 / PB90-1)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Cell wall formation.UniRule annotationSAAS annotation

Catalytic activityi

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.UniRule annotationSAAS annotation

Cofactori

Note: Binds 2 magnesium or manganese ions per subunit.UniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi250 – 2501Magnesium or manganese 1UniRule annotation
Metal bindingi263 – 2631Magnesium or manganese 1UniRule annotation
Metal bindingi263 – 2631Magnesium or manganese 2UniRule annotation
Metal bindingi265 – 2651Magnesium or manganese 2UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi129 – 18254ATPUniRule annotationAdd
BLAST

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. D-alanine-D-alanine ligase activity Source: UniProtKB-HAMAP
  3. magnesium ion binding Source: UniProtKB-HAMAP
  4. manganese ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. cell wall organization Source: UniProtKB-KW
  2. peptidoglycan biosynthetic process Source: UniProtKB-HAMAP
  3. regulation of cell shape Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotationSAAS annotation

Keywords - Biological processi

Cell shape, Cell wall biogenesis/degradationUniRule annotationSAAS annotation, Peptidoglycan synthesisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, MagnesiumUniRule annotationSAAS annotation, ManganeseUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciOTER452637:GHBR-2691-MONOMER.
UniPathwayiUPA00219.

Names & Taxonomyi

Protein namesi
Recommended name:
D-alanine--D-alanine ligaseUniRule annotation (EC:6.3.2.4UniRule annotation)
Alternative name(s):
D-Ala-D-Ala ligaseUniRule annotation
D-alanylalanine synthetaseUniRule annotation
Gene namesi
Name:ddlUniRule annotation
Ordered Locus Names:Oter_2638Imported
OrganismiOpitutus terrae (strain DSM 11246 / PB90-1)Imported
Taxonomic identifieri452637 [NCBI]
Taxonomic lineageiBacteriaVerrucomicrobiaOpitutaeOpitutalesOpitutaceaeOpitutus
ProteomesiUP000007013: Chromosome

Subcellular locationi

Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi452637.Oter_2638.

Structurei

3D structure databases

ProteinModelPortaliB1ZUU9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini101 – 296196ATP-graspUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the D-alanine--D-alanine ligase family.UniRule annotation
Contains 1 ATP-grasp domain.UniRule annotation
Contains ATP-grasp domain.SAAS annotation

Phylogenomic databases

eggNOGiCOG1181.
HOGENOMiHOG000011592.
KOiK01921.
OMAiANDTQYR.
OrthoDBiEOG6ND0KB.

Family and domain databases

Gene3Di3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
HAMAPiMF_00047. Dala_Dala_lig.
InterProiIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERiPTHR23132. PTHR23132. 1 hit.
PfamiPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 2 hits.
[Graphical view]
SUPFAMiSSF52440. SSF52440. 1 hit.
TIGRFAMsiTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEiPS50975. ATP_GRASP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B1ZUU9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDSPVIAVFS GGTSSEREVS LGSGQACAAA LEKSFRVERF QIDADALPAG
60 70 80 90 100
LDPQRHVVFS TLHGTFGEDG GMQRLLDAAG MHYAGCDAVS SALTMDKTLT
110 120 130 140 150
KETAAAKGIK VIPGVTFPAA KKPRPEQVIE QFGERVVVKP NAEGSSVGLN
160 170 180 190 200
LVGSREELTR VLDVIQNGRW IIERRIFGRE LAVGVLNGRA MGVVEIRPKS
210 220 230 240 250
GVYDYASKYT KGMTNYLAPA PLDAALTQKI QAAAQTAFAA CGCRDYARVD
260 270 280 290 300
FILGDDHELY LLEINTLPGM KETSLLPMSA RCEGIDFTAL VKAMVTPAVQ
310
RFHAARASRN P
Length:311
Mass (Da):33,359
Last modified:May 20, 2008 - v1
Checksum:i71076FA149D56C67
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001032 Genomic DNA. Translation: ACB75919.1.
RefSeqiYP_001819519.1. NC_010571.1.

Genome annotation databases

EnsemblBacteriaiACB75919; ACB75919; Oter_2638.
GeneIDi6208021.
KEGGiote:Oter_2638.
PATRICi22816945. VBIOpiTer17422_2745.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001032 Genomic DNA. Translation: ACB75919.1 .
RefSeqi YP_001819519.1. NC_010571.1.

3D structure databases

ProteinModelPortali B1ZUU9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 452637.Oter_2638.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACB75919 ; ACB75919 ; Oter_2638 .
GeneIDi 6208021.
KEGGi ote:Oter_2638.
PATRICi 22816945. VBIOpiTer17422_2745.

Phylogenomic databases

eggNOGi COG1181.
HOGENOMi HOG000011592.
KOi K01921.
OMAi ANDTQYR.
OrthoDBi EOG6ND0KB.

Enzyme and pathway databases

UniPathwayi UPA00219 .
BioCyci OTER452637:GHBR-2691-MONOMER.

Family and domain databases

Gene3Di 3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
HAMAPi MF_00047. Dala_Dala_lig.
InterProi IPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view ]
PANTHERi PTHR23132. PTHR23132. 1 hit.
Pfami PF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 2 hits.
[Graphical view ]
SUPFAMi SSF52440. SSF52440. 1 hit.
TIGRFAMsi TIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEi PS50975. ATP_GRASP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 11246 / PB90-1Imported.

Entry informationi

Entry nameiB1ZUU9_OPITP
AccessioniPrimary (citable) accession number: B1ZUU9
Entry historyi
Integrated into UniProtKB/TrEMBL: May 20, 2008
Last sequence update: May 20, 2008
Last modified: November 26, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3