B1ZTU5 (B1ZTU5_OPITP) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Histidinol-phosphate aminotransferase 2 HAMAP MF_01023
EC=2.6.1.9 HAMAP MF_01023

Alternative name(s):
Imidazole acetol-phosphate transaminase 2 HAMAP MF_01023

Gene names

Name:	hisC2 HAMAP MF_01023
Ordered Locus Names:	Oter_1594

Organism

Opitutus terrae (strain DSM 11246 / PB90-1) [Complete proteome] [HAMAP]

Taxonomic identifier

452637 [NCBI]

Taxonomic lineage

Bacteria › Verrucomicrobia › Opitutae › Opitutales › Opitutaceae › Opitutus

Protein attributes

Sequence length	365 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-histidinol phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate. HAMAP MF_01023 SAAS SAAS005861
Cofactor	Pyridoxal phosphate By similarity. HAMAP MF_01023 SAAS SAAS005861
Pathway	Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9. HAMAP MF_01023 SAAS SAAS005861
Subunit structure	Homodimer By similarity. HAMAP MF_01023
Sequence similarities	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. HAMAP MF_01023

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Histidine biosynthesis HAMAP MF_01023 SAAS SAAS005861
Ligand	Pyridoxal phosphate HAMAP MF_01023 SAAS SAAS005861
Molecular function	Aminotransferase HAMAP MF_01023 SAAS SAAS005861 EMBL ACB74878.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	histidine biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	L-phenylalanine:2-oxoglutarate aminotransferase activity Inferred from electronic annotation. Source: EC histidinol-phosphate transaminase activity Inferred from electronic annotation. Source: HAMAP pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Amino acid modifications
	Modified residue	226	1	N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_01023

Sequences

	Sequence		Length	Mass (Da)
	B1ZTU5 [UniParc]. Last modified May 20, 2008. Version 1. Checksum: EB4903D11A14765B	FASTA	365	39,571
	10 20 30 40 50 60 MNFQALVKPA VLTQPVYEPG KPIETVAREL GLDPAGIIKL ASNENAFGPS PRAVAAANLA 70 80 90 100 110 120 LGEGELYPDG GCFALREKLA QVRGLAPDQF IIGNGSNEII ELLGHALIGA GDEVVMGSPA 130 140 150 160 170 180 FVVYKLVTLV FGGKAVEVPL VNHRHDLPAI RAAITPRTKL VYVCSPNNPT GTANTEEELL 190 200 210 220 230 240 TFARSLPEHV VAVFDEAYAE YIPQAPDLRP LLREGRNVIC LRTFSKIYGL ASLRIGYGYA 250 260 270 280 290 300 AAETIALLNR VRQPFNVNAI AQAAAVAALD DIEFTTRCRD ANLAGLRQLE AGFRKLGLEY 310 320 330 340 350 360 VPSVANFLVV RVGDGARVFD ALQRRGVIVR PLKPYAMPEW LRVTVGTPQQ NDRLLAELAR YRDNP

References

[1]

"Complete sequence of Opitutus terrae PB90-1." Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Pitluck S., Goltsman E., Clum A., Sun H., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Smidt H., Richardson P. Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 11246 / PB90-1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001032 Genomic DNA. Translation: ACB74878.1.
RefSeq	YP_001818478.1. NC_010571.1.
3D structure databases
ProteinModelPortal	B1ZTU5.
ModBase	Search...
Protein-protein interaction databases
STRING	B1ZTU5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6206663.
GenomeReviews	Gene locus Oter_1594 in contig CP001032_GR.
KEGG	ote:Oter_1594.
PATRIC	22814719. VBIOpiTer17422_1654.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG646350.
OMA	ASNENAF.
ProtClustDB	CLSK2542702.
Family and domain databases
HAMAP	MF_01023. HisC_aminotrans_2. [Tree]
InterPro	IPR004839. Aminotransferase_I/II. IPR005861. HisP_aminotrans. IPR015424. PyrdxlP-dep_Trfase_major_dom. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view]
Gene3D	G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit. G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KO	K00817.
Pfam	PF00155. Aminotran_1_2. 1 hit. [Graphical view]
SUPFAM	SSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMs	TIGR01141. HisC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B1ZTU5_OPITP

Accession

Primary (citable) accession number: B1ZTU5

Entry history

Integrated into UniProtKB/TrEMBL:	May 20, 2008
Last sequence update:	May 20, 2008
Last modified:	December 14, 2011
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)