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B1ZS98

- PNP_OPITP

UniProt

B1ZS98 - PNP_OPITP

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Protein
Polyribonucleotide nucleotidyltransferase
Gene
pnp, Oter_2415
Organism
Opitutus terrae (strain DSM 11246 / PB90-1)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction By similarity.UniRule annotation

Catalytic activityi

RNA(n+1) + phosphate = RNA(n) + a nucleoside diphosphate.UniRule annotation

Cofactori

Magnesium By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi494 – 4941Magnesium By similarity
Metal bindingi500 – 5001Magnesium By similarity

GO - Molecular functioni

  1. 3'-5'-exoribonuclease activity Source: InterPro
  2. RNA binding Source: UniProtKB-HAMAP
  3. magnesium ion binding Source: UniProtKB-HAMAP
  4. polyribonucleotide nucleotidyltransferase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. RNA processing Source: InterPro
  2. mRNA catabolic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Ligandi

Magnesium, Metal-binding, RNA-binding

Enzyme and pathway databases

BioCyciOTER452637:GHBR-2466-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Polyribonucleotide nucleotidyltransferase (EC:2.7.7.8)
Alternative name(s):
Polynucleotide phosphorylase
Short name:
PNPase
Gene namesi
Name:pnp
Ordered Locus Names:Oter_2415
OrganismiOpitutus terrae (strain DSM 11246 / PB90-1)
Taxonomic identifieri452637 [NCBI]
Taxonomic lineageiBacteriaVerrucomicrobiaOpitutaeOpitutalesOpitutaceaeOpitutus
ProteomesiUP000007013: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 730730Polyribonucleotide nucleotidyltransferaseUniRule annotation
PRO_0000381908Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi452637.Oter_2415.

Structurei

3D structure databases

ProteinModelPortaliB1ZS98.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini561 – 62262KH
Add
BLAST
Domaini642 – 71170S1 motif
Add
BLAST

Sequence similaritiesi

Contains 1 KH domain.
Contains 1 S1 motif domain.

Phylogenomic databases

eggNOGiCOG1185.
HOGENOMiHOG000218326.
KOiK00962.
OMAiPRWDWVA.
OrthoDBiEOG6WT8CC.

Family and domain databases

Gene3Di1.10.10.400. 1 hit.
2.40.50.140. 1 hit.
3.30.1370.10. 1 hit.
3.30.230.70. 2 hits.
HAMAPiMF_01595. PNPase.
InterProiIPR001247. ExoRNase_PH_dom1.
IPR015847. ExoRNase_PH_dom2.
IPR004087. KH_dom.
IPR004088. KH_dom_type_1.
IPR012340. NA-bd_OB-fold.
IPR012162. PNPase.
IPR027408. PNPase/RNase_PH_dom.
IPR015848. PNPase_PH_RNA-bd_bac/org-type.
IPR003029. Rbsml_prot_S1_RNA-bd_dom.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR022967. RNA-binding_domain_S1.
[Graphical view]
PANTHERiPTHR11252. PTHR11252. 1 hit.
PfamiPF00013. KH_1. 1 hit.
PF03726. PNPase. 1 hit.
PF01138. RNase_PH. 2 hits.
PF03725. RNase_PH_C. 1 hit.
PF00575. S1. 1 hit.
[Graphical view]
PIRSFiPIRSF005499. PNPase. 1 hit.
SMARTiSM00322. KH. 1 hit.
SM00316. S1. 1 hit.
[Graphical view]
SUPFAMiSSF46915. SSF46915. 1 hit.
SSF50249. SSF50249. 1 hit.
SSF54211. SSF54211. 2 hits.
SSF54791. SSF54791. 1 hit.
SSF55666. SSF55666. 2 hits.
TIGRFAMsiTIGR03591. polynuc_phos. 1 hit.
PROSITEiPS50084. KH_TYPE_1. 1 hit.
PS50126. S1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B1ZS98-1 [UniParc]FASTAAdd to Basket

« Hide

MNQKYSVTVP ELGITFSTGS IAQLANGAVN VQVGETNVFV TACVAQTTKP    50
GQDWFPLTVD YREKYAAAGR FPGGYFKREG RPSEKEILTS RLCDRPCRPL 100
FPEGFLNEVQ IIGQLFSADL VNESDISMVN GASAALAISD IPWNGPIAAV 150
RVAEIEGKFV ANPTIDQMFA SSLDLIYVGN EKDMLMIEGS ADQIPEERFI 200
EALAFGHESI QPILKAIKEL VAQCGKPKGT FPLVGATPEA RTIIERVVPT 250
ERLIEAIFGK EKAVRANAVK LLKEEAKAAL TAELGEGKFT DVDLNVVFED 300
LQYKAYRKTV LERGVRADGR GQKDIRPLQA QVGVLPRVHG SAMFQRGDTQ 350
NIALTTLGPT KDAQDLDALT GGVKSKSFLL HYNFPPFSVG ETGRFTGPGR 400
REIGHGALAE RSLVPVLPPE DVFPYSIRVV SEIMASNGST SMASICGGCL 450
SLMDAGVPII APVAGISCGL MTQNASDGSI EKWVTITDIL GEEDHFGDMD 500
FKLAGTSKGI TGFQLDLKIN GLPFEIAKTA IMQARDARME ILKVMLGSLP 550
APRADLSKYA PRIQTIQIDP EKIGLLIGPG GKTIRRITET TGAQIDIAED 600
DSGKVFVYSN NAEAMNRAIQ EIDSLCGGGG PGGSKGPAIE VGKIYTGRVT 650
GVKEFGCFVE CTPGNEGLCH VSELADFRVR RTEDVVKMGD SITVKCIGID 700
ERSGKVRLSR KAAMKELEAQ KQSSEAAPAQ 730
Length:730
Mass (Da):78,463
Last modified:May 20, 2008 - v1
Checksum:i8D75403DC2DF0304
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001032 Genomic DNA. Translation: ACB75697.1.
RefSeqiWP_012375233.1. NC_010571.1.
YP_001819297.1. NC_010571.1.

Genome annotation databases

EnsemblBacteriaiACB75697; ACB75697; Oter_2415.
GeneIDi6207731.
KEGGiote:Oter_2415.
PATRICi22816489. VBIOpiTer17422_2519.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001032 Genomic DNA. Translation: ACB75697.1 .
RefSeqi WP_012375233.1. NC_010571.1.
YP_001819297.1. NC_010571.1.

3D structure databases

ProteinModelPortali B1ZS98.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 452637.Oter_2415.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACB75697 ; ACB75697 ; Oter_2415 .
GeneIDi 6207731.
KEGGi ote:Oter_2415.
PATRICi 22816489. VBIOpiTer17422_2519.

Phylogenomic databases

eggNOGi COG1185.
HOGENOMi HOG000218326.
KOi K00962.
OMAi PRWDWVA.
OrthoDBi EOG6WT8CC.

Enzyme and pathway databases

BioCyci OTER452637:GHBR-2466-MONOMER.

Family and domain databases

Gene3Di 1.10.10.400. 1 hit.
2.40.50.140. 1 hit.
3.30.1370.10. 1 hit.
3.30.230.70. 2 hits.
HAMAPi MF_01595. PNPase.
InterProi IPR001247. ExoRNase_PH_dom1.
IPR015847. ExoRNase_PH_dom2.
IPR004087. KH_dom.
IPR004088. KH_dom_type_1.
IPR012340. NA-bd_OB-fold.
IPR012162. PNPase.
IPR027408. PNPase/RNase_PH_dom.
IPR015848. PNPase_PH_RNA-bd_bac/org-type.
IPR003029. Rbsml_prot_S1_RNA-bd_dom.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR022967. RNA-binding_domain_S1.
[Graphical view ]
PANTHERi PTHR11252. PTHR11252. 1 hit.
Pfami PF00013. KH_1. 1 hit.
PF03726. PNPase. 1 hit.
PF01138. RNase_PH. 2 hits.
PF03725. RNase_PH_C. 1 hit.
PF00575. S1. 1 hit.
[Graphical view ]
PIRSFi PIRSF005499. PNPase. 1 hit.
SMARTi SM00322. KH. 1 hit.
SM00316. S1. 1 hit.
[Graphical view ]
SUPFAMi SSF46915. SSF46915. 1 hit.
SSF50249. SSF50249. 1 hit.
SSF54211. SSF54211. 2 hits.
SSF54791. SSF54791. 1 hit.
SSF55666. SSF55666. 2 hits.
TIGRFAMsi TIGR03591. polynuc_phos. 1 hit.
PROSITEi PS50084. KH_TYPE_1. 1 hit.
PS50126. S1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 11246 / PB90-1.

Entry informationi

Entry nameiPNP_OPITP
AccessioniPrimary (citable) accession number: B1ZS98
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 1, 2009
Last sequence update: May 20, 2008
Last modified: September 3, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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