B1ZMU2 (B1ZMU2_OPITP) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Lipid-A-disaccharide synthase EMBL ACB75370.1
EC=2.4.1.182 EMBL ACB75370.1

Gene names

Ordered Locus Names:

Oter_2087

Organism

Opitutus terrae (strain DSM 11246 / PB90-1) [Complete proteome] [HAMAP]

Taxonomic identifier

452637 [NCBI]

Taxonomic lineage

Bacteria › Verrucomicrobia › Opitutae › Opitutales › Opitutaceae › Opitutus

Protein attributes

Sequence length	389 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS003835
Catalytic activity	UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. SAAS SAAS003835
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 5/6. SAAS SAAS003835

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS003835 Lipid synthesis
Molecular function	Glycosyltransferase SAAS SAAS003835 EMBL ACB75370.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	lipid-A-disaccharide synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B1ZMU2 [UniParc]. Last modified May 20, 2008. Version 1. Checksum: B3AA9CF2D3BD6B5B	FASTA	389	41,662
	10 20 30 40 50 60 MSSSPTVHLP SSTSGRVDVL IIAGEHSGDE HAARMVRELR AKQPGIAIAA LGGPELAAAG 70 80 90 100 110 120 AQLLFDLTAS SVVGLVEVLK HYGFFKALFA DTLRWIAEHQ PRAVCFIDYP GFNLRIAAAL 130 140 150 160 170 180 HERGLSVKGG GRIKCLFYIS PQIWAWKAGR RFTMARDLDA MATIFPFEPQ CYADTTLPVE 190 200 210 220 230 240 FVGHPFVAPD YVSPVRHDPA GPVLLLPGSR KQAVGRIFPA LLAGFREFGE RDAVVLYPSD 250 260 270 280 290 300 EIRTVLEAEN PPANVRLVEI DAHGGTAGGV ALPVAATLTS SGTMSMHCAL AAIPGAIAYR 310 320 330 340 350 360 ANPLTYVLGK MLVRVPYLGI ANLLLNEPMY PEYLQGAATP QALAAELRAS VHDPERQAKT 370 380 AEQSARLRAL LSQPTGGSAA DWVVRQMTG

References

[1]

"Complete sequence of Opitutus terrae PB90-1." Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Pitluck S., Goltsman E., Clum A., Sun H., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Smidt H., Richardson P. Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 11246 / PB90-1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001032 Genomic DNA. Translation: ACB75370.1.
RefSeq	YP_001818970.1. NC_010571.1.
3D structure databases
ProteinModelPortal	B1ZMU2.
ModBase	Search...
Protein-protein interaction databases
STRING	B1ZMU2.
Protein family/group databases
CAZy	GT19. Glycosyltransferase Family 19.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6207112.
GenomeReviews	Gene locus Oter_2087 in contig CP001032_GR.
KEGG	ote:Oter_2087.
PATRIC	22815775. VBIOpiTer17422_2171.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG584837.
OMA	IGLANIM.
ProtClustDB	CLSK2800455.
Family and domain databases
InterPro	IPR003835. Glyco_trans_19. [Graphical view]
KO	K00748.
Pfam	PF02684. LpxB. 1 hit. [Graphical view]
TIGRFAMs	TIGR00215. LpxB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B1ZMU2_OPITP

Accession

Primary (citable) accession number: B1ZMU2

Entry history

Integrated into UniProtKB/TrEMBL:	May 20, 2008
Last sequence update:	May 20, 2008
Last modified:	December 14, 2011
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)