B1ZFB6 (B1ZFB6_METPB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut EMBL ACB79689.1
EC=3.6.1.23 EMBL ACB79689.1

Gene names

Ordered Locus Names:

Mpop_1523

Organism

Methylobacterium populi (strain ATCC BAA-705 / NCIMB 13946 / BJ001) [Complete proteome] [HAMAP]

Taxonomic identifier

441620 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Methylobacteriaceae › Methylobacterium

Protein attributes

Sequence length	162 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA By similarity. SAAS SAAS008181
Catalytic activity	dUTP + H2O = dUMP + diphosphate. SAAS SAAS008181
Cofactor	Magnesium By similarity. SAAS SAAS008181

Ontologies

Keywords
Biological process	Nucleotide metabolism SAAS SAAS008181
Ligand	Magnesium SAAS SAAS008181 Metal-binding SAAS SAAS008181
Molecular function	Hydrolase SAAS SAAS008181 EMBL ACB79689.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	dUTP diphosphatase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B1ZFB6 [UniParc]. Last modified May 20, 2008. Version 1. Checksum: DBAE66C568661376	FASTA	162	16,791
	10 20 30 40 50 60 MKVGLHILDP RLTGWGFPRW GSAAAAGLDL HACLDAALPL EPQAPPALIP AGVSVRIGDP 70 80 90 100 110 120 DWCGLVFPRS GLGHREGLVL GNGTGVIDAD YEGPLLISAW NRNPPGGAAI RIEPGERIAQ 130 140 150 160 LVFTRVMRPD FEIREGMPAP EGSAAGEGAG RGAGGFGSTG RR

References

[1]

"Complete sequence of chromosome of Methylobacterium populi BJ001." Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L. , Kyrpides N., Mikhailova N., Marx C., Richardson P. Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-705 / NCIMB 13946 / BJ001.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001029 Genomic DNA. Translation: ACB79689.1.
RefSeq	YP_001924224.1. NC_010725.1.
3D structure databases
ProteinModelPortal	B1ZFB6.
ModBase	Search...
Protein-protein interaction databases
STRING	B1ZFB6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6309129.
GenomeReviews	Gene locus Mpop_1523 in contig CP001029_GR.
KEGG	mpo:Mpop_1523.
PATRIC	22560277. VBIMetPop124700_1558.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG436079.
OMA	LDLRACI.
ProtClustDB	CLSK2330713.
Family and domain databases
InterPro	IPR008180. dUTP_pyroPase. IPR008181. dUTP_pyroPase_sf. [Graphical view]
KO	K01520.
PANTHER	PTHR11241. PTHR11241. 1 hit.
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00576. Dut. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B1ZFB6_METPB

Accession

Primary (citable) accession number: B1ZFB6

Entry history

Integrated into UniProtKB/TrEMBL:	May 20, 2008
Last sequence update:	May 20, 2008
Last modified:	December 14, 2011
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)