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Protein

Alanine racemase

Gene

Mpop_4410

Organism
Methylobacterium populi (strain ATCC BAA-705 / NCIMB 13946 / BJ001)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotationSAAS annotation

Pathwayi: D-alanine biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes D-alanine from L-alanine.UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Alanine racemase (Mpop_4410)
This subpathway is part of the pathway D-alanine biosynthesis, which is itself part of Amino-acid biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-alanine from L-alanine, the pathway D-alanine biosynthesis and in Amino-acid biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei43Proton acceptor; specific for D-alanineUniRule annotation1
Binding sitei138SubstrateUniRule annotation1
Active sitei259Proton acceptor; specific for L-alanineUniRule annotation1
Binding sitei307Substrate; via amide nitrogenUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotationImported
LigandPyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciMPOP441620:GHMI-4380-MONOMER
UniPathwayiUPA00042; UER00497

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Mpop_4410Imported
OrganismiMethylobacterium populi (strain ATCC BAA-705 / NCIMB 13946 / BJ001)Imported
Taxonomic identifieri441620 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesMethylobacteriaceaeMethylobacterium
Proteomesi
  • UP000007136 Componenti: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei43N6-(pyridoxal phosphate)lysineUniRule annotation1

Interactioni

Protein-protein interaction databases

STRINGi441620.Mpop_4410

Structurei

3D structure databases

ProteinModelPortaliB1ZEY2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini238 – 362Ala_racemase_CInterPro annotationAdd BLAST125

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CJ4 Bacteria
COG0787 LUCA
HOGENOMiHOG000031445
KOiK01775
OMAiWRGPILL
OrthoDBiPOG091H022F

Family and domain databases

Gene3Di2.40.37.101 hit
3.20.20.101 hit
HAMAPiMF_01201 Ala_racemase, 1 hit
InterProiView protein in InterPro
IPR000821 Ala_racemase
IPR009006 Ala_racemase/Decarboxylase_C
IPR011079 Ala_racemase_C
IPR001608 Ala_racemase_N
IPR020622 Ala_racemase_pyridoxalP-BS
IPR029066 PLP-binding_barrel
PfamiView protein in Pfam
PF00842 Ala_racemase_C, 1 hit
PF01168 Ala_racemase_N, 1 hit
PRINTSiPR00992 ALARACEMASE
SMARTiView protein in SMART
SM01005 Ala_racemase_C, 1 hit
SUPFAMiSSF50621 SSF50621, 1 hit
SSF51419 SSF51419, 1 hit
TIGRFAMsiTIGR00492 alr, 1 hit
PROSITEiView protein in PROSITE
PS00395 ALANINE_RACEMASE, 1 hit

Sequencei

Sequence statusi: Complete.

B1ZEY2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGDSFADPG HGARLTVDLA AIAANWRALG ACAPQAECGA VVKADAYGCG
60 70 80 90 100
LAAVAPALWR AGCRTFFVAH LSEGIAARKI LPEAAIYVLN GLVPGHAEAF
110 120 130 140 150
RAHGLRPVLG DRGELLEWAA ATDGAAPAAL HVDTGMNRLG LRVEEALALA
160 170 180 190 200
GDPLIARAGI DLVMSHLVSA ERPDDPLNAG QAEAFARVRD AFPPLRASLA
210 220 230 240 250
NSSGTCLAAR ARHDLLRPGY ALFGGNPEPG QRNPMRPVVR LEATILQLRA
260 270 280 290 300
VEAGESCGYN GRWQAPAPRR LATLSLGYAD GYPRSASNSG HALVGGVPCP
310 320 330 340 350
IVGLISMDLI ILDVTDASEA RRGATATLIG DSLDIDTVGQ AAGTIGYEIL
360
TGLGSRYVRS YVE
Length:363
Mass (Da):37,679
Last modified:May 20, 2008 - v1
Checksum:iB822520BC2EF6F2A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001029 Genomic DNA Translation: ACB82510.1

Genome annotation databases

EnsemblBacteriaiACB82510; ACB82510; Mpop_4410
KEGGimpo:Mpop_4410

Similar proteinsi

Entry informationi

Entry nameiB1ZEY2_METPB
AccessioniPrimary (citable) accession number: B1ZEY2
Entry historyiIntegrated into UniProtKB/TrEMBL: May 20, 2008
Last sequence update: May 20, 2008
Last modified: April 25, 2018
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported