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B1ZEF2 (B1ZEF2_METPB) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferrochelatase HAMAP MF_00323 RuleBase RU000607
EC=4.99.1.1 HAMAP MF_00323 RuleBase RU000607
Alternative name(s):
Heme synthase HAMAP MF_00323
Protoheme ferro-lyase HAMAP MF_00323
Gene names
Name:hemH HAMAP MF_00323
Ordered Locus Names:Mpop_1470
OrganismMethylobacterium populi (strain ATCC BAA-705 / NCIMB 13946 / BJ001) [Complete proteome] [HAMAP]
Taxonomic identifier441620 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Methylobacteriaceae › Methylobacterium

Protein attributes

Sequence length356 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ferrous insertion into protoporphyrin IX By similarity. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Catalytic activity

Protoheme + 2 H+ = protoporphyrin + Fe2+. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Pathway

Porphyrin metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Subcellular location

Cytoplasm By similarity HAMAP MF_00323.

Sequence similarities

Belongs to the ferrochelatase family. HAMAP MF_00323 RuleBase RU004185

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding2261Iron By similarity HAMAP MF_00323
Metal binding3071Iron By similarity HAMAP MF_00323

Sequences

Sequence LengthMass (Da)Tools
B1ZEF2 [UniParc].

Last modified May 20, 2008. Version 1.
Checksum: 8CDA342BDD3CDACA

FASTA35640,580
        10         20         30         40         50         60 
MNERVEPDTL LRNPVRVAPT ALPPDHPAVR TGRVGVLLMN LGTPEGTSYW PMRRYLKEFL 

        70         80         90        100        110        120 
SDRRVIEVPR LIWWPLLNLI ILTKRPGPKG RDYASIWNNE RDEGPLKTIT RGQCEKLQAA 

       130        140        150        160        170        180 
MGDSVVVDWA MRYGKPEVSL RIQALLDQGC DRILLVPLYP QYAAATSATA CDQAFKALMQ 

       190        200        210        220        230        240 
MRWQPTVRVS PPYHDDPVYI EAMADSIREG LAKLDFEPEV ILTSFHGVPK SYLLKGDPYH 

       250        260        270        280        290        300 
CQCLKTGRLI REAMGYTPEQ MRVTFQSRFG NEEWLKPYTD ETVQALAKSG VKRMAIVAPG 

       310        320        330        340        350 
FTADCLETLE ELDGENRHYF EENGGEKYAF IPCLNDSDLG MRVIEHVVRR ELQGWI

« Hide

References

[1]"Complete sequence of chromosome of Methylobacterium populi BJ001."
Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L. expand/collapse author list , Kyrpides N., Mikhailova N., Marx C., Richardson P.
Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-705 / NCIMB 13946 / BJ001.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001029 Genomic DNA. Translation: ACB79637.1.
RefSeqYP_001924172.1. NC_010725.1.

3D structure databases

ProteinModelPortalB1ZEF2.
ModBaseSearch...

Protein-protein interaction databases

STRINGB1ZEF2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6313466.
GenomeReviewsGene locus Mpop_1470 in contig CP001029_GR.
KEGGmpo:Mpop_1470.
PATRIC22560170. VBIMetPop124700_1505.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG697135.
OMAIRPAKSA.
ProtClustDBCLSK979865.

Family and domain databases

HAMAPMF_00323. Ferrochelatase.
[Tree]
InterProIPR001015. Ferrochelatase.
IPR019772. Ferrochelatase_AS.
[Graphical view]
KOK01772.
PANTHERPTHR11108. Ferrochelatase. 1 hit.
PfamPF00762. Ferrochelatase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00109. HemH. 1 hit.
PROSITEPS00534. FERROCHELATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB1ZEF2_METPB
AccessionPrimary (citable) accession number: B1ZEF2
Entry history
Integrated into UniProtKB/TrEMBL: May 20, 2008
Last sequence update: May 20, 2008
Last modified: December 14, 2011
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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