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Protein

Pantothenate kinase

Gene

coaA

Organism
Methylobacterium populi (strain ATCC BAA-705 / NCIMB 13946 / BJ001)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (R)-pantothenate = ADP + (R)-4'-phosphopantothenate.UniRule annotationSAAS annotation

Pathwayi

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi115 – 1228ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. pantothenate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. coenzyme A biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotation, Transferase

Keywords - Biological processi

Coenzyme A biosynthesisUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciMPOP441620:GHMI-2535-MONOMER.
UniPathwayiUPA00241; UER00352.

Names & Taxonomyi

Protein namesi
Recommended name:
Pantothenate kinaseUniRule annotation (EC:2.7.1.33UniRule annotation)
Alternative name(s):
Pantothenic acid kinaseUniRule annotation
Gene namesi
Name:coaAUniRule annotation
Ordered Locus Names:Mpop_2485Imported
OrganismiMethylobacterium populi (strain ATCC BAA-705 / NCIMB 13946 / BJ001)Imported
Taxonomic identifieri441620 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesMethylobacteriaceaeMethylobacterium
ProteomesiUP000007136: Chromosome

Subcellular locationi

Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi441620.Mpop_2485.

Structurei

3D structure databases

ProteinModelPortaliB1ZAD8.
SMRiB1ZAD8. Positions 28-337.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the prokaryotic pantothenate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1072.
HOGENOMiHOG000248571.
KOiK00867.
OMAiWPEHPRV.
OrthoDBiEOG62C9GX.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00215. Pantothen_kinase_1.
InterProiIPR027417. P-loop_NTPase.
IPR004566. PanK_bact.
IPR006083. PRK/URK.
[Graphical view]
PANTHERiPTHR10285:SF7. PTHR10285:SF7. 1 hit.
PfamiPF00485. PRK. 1 hit.
[Graphical view]
PIRSFiPIRSF000545. Pantothenate_kin. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00554. panK_bact. 1 hit.

Sequencei

Sequence statusi: Complete.

B1ZAD8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MIGAPIPSAG IEPEERQNPV TGQGPSRLSP YRIFSRDEWA QLRADTPLTL
60 70 80 90 100
TAEDIGRLQS LNDPISIEEV VAIYLPLSRL LSLYVAATQG LFKATQRFLL
110 120 130 140 150
AEHDAKVPYI IGLAGSVAVG KSTTARVLKA LLARWPNTPK VDLITTDGFL
160 170 180 190 200
HPNAELQRMG AMERKGFPES YDSAALLRFL ADIKAGHKHV AAPVYSHLVY
210 220 230 240 250
DVVPGEEQVI ESPDILIVEG LNVLQPARLP RDGTAIPFVS DFFDFSIYLD
260 270 280 290 300
GHEDDLHRWY VNRFLRLRQT AFRDPLSYFR KYAEVTEGEA LDIADRLWTT
310 320 330
INLPNLRDNI LPTRQRASLI LAKGPSHRIE SVALRRL
Length:337
Mass (Da):37,710
Last modified:May 20, 2008 - v1
Checksum:iFBFEC56CDF4D6776
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001029 Genomic DNA. Translation: ACB80646.1.
RefSeqiWP_012454376.1. NC_010725.1.
YP_001925181.1. NC_010725.1.

Genome annotation databases

EnsemblBacteriaiACB80646; ACB80646; Mpop_2485.
GeneIDi6313052.
KEGGimpo:Mpop_2485.
PATRICi22562260. VBIMetPop124700_2541.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001029 Genomic DNA. Translation: ACB80646.1.
RefSeqiWP_012454376.1. NC_010725.1.
YP_001925181.1. NC_010725.1.

3D structure databases

ProteinModelPortaliB1ZAD8.
SMRiB1ZAD8. Positions 28-337.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi441620.Mpop_2485.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACB80646; ACB80646; Mpop_2485.
GeneIDi6313052.
KEGGimpo:Mpop_2485.
PATRICi22562260. VBIMetPop124700_2541.

Phylogenomic databases

eggNOGiCOG1072.
HOGENOMiHOG000248571.
KOiK00867.
OMAiWPEHPRV.
OrthoDBiEOG62C9GX.

Enzyme and pathway databases

UniPathwayiUPA00241; UER00352.
BioCyciMPOP441620:GHMI-2535-MONOMER.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00215. Pantothen_kinase_1.
InterProiIPR027417. P-loop_NTPase.
IPR004566. PanK_bact.
IPR006083. PRK/URK.
[Graphical view]
PANTHERiPTHR10285:SF7. PTHR10285:SF7. 1 hit.
PfamiPF00485. PRK. 1 hit.
[Graphical view]
PIRSFiPIRSF000545. Pantothenate_kin. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00554. panK_bact. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of chromosome of Methylobacterium populi BJ001."
    US DOE Joint Genome Institute
    Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L.
    , Kyrpides N., Mikhailova N., Marx C., Richardson P.
    Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-705 / NCIMB 13946 / BJ001Imported.

Entry informationi

Entry nameiB1ZAD8_METPB
AccessioniPrimary (citable) accession number: B1ZAD8
Entry historyi
Integrated into UniProtKB/TrEMBL: May 20, 2008
Last sequence update: May 20, 2008
Last modified: February 4, 2015
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.