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B1Z8W8 (B1Z8W8_METPB) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
UDP-N-acetylmuramoylalanine--D-glutamate ligase HAMAP-Rule MF_00639 RuleBase RU003664

EC=6.3.2.9 HAMAP-Rule MF_00639 RuleBase RU003664
Alternative name(s):
D-glutamic acid-adding enzyme HAMAP-Rule MF_00639
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase HAMAP-Rule MF_00639
Gene names
Name:murD HAMAP-Rule MF_00639
Ordered Locus Names:Mpop_5174 EMBL ACB83268.1
OrganismMethylobacterium populi (strain ATCC BAA-705 / NCIMB 13946 / BJ001) [Complete proteome] [HAMAP] EMBL ACB83268.1
Taxonomic identifier441620 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesMethylobacteriaceaeMethylobacterium

Protein attributes

Sequence length455 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) By similarity. HAMAP-Rule MF_00639 SAAS SAAS005762

Catalytic activity

ATP + UDP-N-acetylmuramoyl-L-alanine + glutamate = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate. HAMAP-Rule MF_00639 SAAS SAAS005762

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00639 SAAS SAAS005762

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00639 SAAS SAAS005762.

Sequence similarities

Belongs to the MurCDEF family. HAMAP-Rule MF_00639 RuleBase RU003630

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 3131 Potential EMBL ACB83268.1
Chain32 – 455424 Potential EMBL ACB83268.1
PRO_5000334233

Regions

Nucleotide binding121 – 1277ATP By similarity HAMAP-Rule MF_00639

Sequences

Sequence LengthMass (Da)Tools
B1Z8W8 [UniParc].

Last modified May 20, 2008. Version 1.
Checksum: F0D74AD6D6C13473

FASTA45547,273
        10         20         30         40         50         60 
MTPATTFAGQ KLALFGLGGS GLATVRSLLA GGADVLAWDD NAGSRDRARE QGITVTDLND 

        70         80         90        100        110        120 
ADWSGFSALV LAPGVPLTHP EPHWTVGLAQ QAGIPIIGDI EIFCRERAAL APEAPFVAIT 

       130        140        150        160        170        180 
GTNGKSTTTA LTAHLLRHAG RDVQMGGNIG TAVLSLAPPA ENRVHVVELS SFQIDLTPSL 

       190        200        210        220        230        240 
DPSVGILLNL TPDHLDRHGT MENYAAIKER LVAGSDLAVI GVDDAYCAAI AGRRRGERIR 

       250        260        270        280        290        300 
LHVEGHGDAA GDYVCRAGAV RGPDGAVIAE ISGIQSLLGE HNLQNAAAAV AAALRLGLTG 

       310        320        330        340        350        360 
AEIAAGLKSF PGLAHRMEPL RRIGPTLFVN DSKATNADST EKALLAFRDI HWIVGGKAKE 

       370        380        390        400        410        420 
GGIEPLAPLF DRVAHAYLIG ASSDAFAATL DGRLPFTRCD TLEAATAAAA QAARASATDA 

       430        440        450 
PVVLLSPACA SYDQFPNFEV RGDRFRALVA ALPEA 

« Hide

References

[1]"Complete sequence of chromosome of Methylobacterium populi BJ001."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L. expand/collapse author list , Kyrpides N., Mikhailova N., Marx C., Richardson P.
Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-705 / NCIMB 13946 / BJ001.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001029 Genomic DNA. Translation: ACB83268.1.
RefSeqYP_001927803.1. NC_010725.1.

3D structure databases

ProteinModelPortalB1Z8W8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING441620.Mpop_5174.

Proteomic databases

PRIDEB1Z8W8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACB83268; ACB83268; Mpop_5174.
GeneID6312528.
KEGGmpo:Mpop_5174.
PATRIC22567614. VBIMetPop124700_5198.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0771.
HOGENOMHOG000049428.
KOK01925.
OMAYCFGQDG.
OrthoDBEOG6HXJ9C.

Enzyme and pathway databases

BioCycMPOP441620:GHMI-5244-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.40.1190.10. 1 hit.
3.40.50.720. 1 hit.
3.90.190.20. 1 hit.
HAMAPMF_00639. MurD.
InterProIPR018109. Folylpolyglutamate_synth_CS.
IPR004101. Mur_ligase_C.
IPR013221. Mur_ligase_cen.
IPR016040. NAD(P)-bd_dom.
IPR005762. UDP-N-AcMur-Glu_ligase.
[Graphical view]
PfamPF02875. Mur_ligase_C. 1 hit.
PF08245. Mur_ligase_M. 1 hit.
[Graphical view]
SUPFAMSSF53244. SSF53244. 1 hit.
SSF53623. SSF53623. 1 hit.
TIGRFAMsTIGR01087. murD. 1 hit.
PROSITEPS01011. FOLYLPOLYGLU_SYNT_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB1Z8W8_METPB
AccessionPrimary (citable) accession number: B1Z8W8
Entry history
Integrated into UniProtKB/TrEMBL: May 20, 2008
Last sequence update: May 20, 2008
Last modified: June 11, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)