Skip Header

Contribute Send feedback
Read comments (?) or add your own

B1Z1L1 (B1Z1L1_BURA4) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Malate dehydrogenase 1 HAMAP MF_01517
EC=1.1.1.37 HAMAP MF_01517
Gene names
Name:mdh1 HAMAP MF_01517
Ordered Locus Names:BamMC406_3825
OrganismBurkholderia ambifaria (strain MC40-6) [Complete proteome] [HAMAP]
Taxonomic identifier398577 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length328 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the reversible oxidation of malate to oxaloacetate By similarity. HAMAP MF_01517

Catalytic activity

(S)-malate + NAD+ = oxaloacetate + NADH. HAMAP MF_01517 SAAS SAAS010945

Subunit structure

Homodimer By similarity. HAMAP MF_01517 SAAS SAAS010945

Sequence similarities

Belongs to the LDH/MDH superfamily. MDH type 2 family. HAMAP MF_01517

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding12 – 187NAD By similarity HAMAP MF_01517
Nucleotide binding130 – 1323NAD By similarity HAMAP MF_01517

Sites

Active site1881Proton acceptor By similarity HAMAP MF_01517
Binding site931Substrate By similarity HAMAP MF_01517
Binding site991Substrate By similarity HAMAP MF_01517
Binding site1061NAD By similarity HAMAP MF_01517
Binding site1131NAD By similarity HAMAP MF_01517
Binding site1321Substrate By similarity HAMAP MF_01517
Binding site1631Substrate By similarity HAMAP MF_01517

Sequences

Sequence LengthMass (Da)Tools
B1Z1L1 [UniParc].

Last modified May 20, 2008. Version 1.
Checksum: 93DE88B218FE3F67

FASTA32835,115
        10         20         30         40         50         60 
MAKPAKRVAV TGAAGQIAYS LLFRIANGDL LGKDQPVILQ LLDLPQAQAA VKGVVMELDD 

        70         80         90        100        110        120 
CAFPLLAGVV ITDDPKVAFK DADVALLVGA RPRSKGMERK DLLSANAEIF TVQGAALNEV 

       130        140        150        160        170        180 
ASRDVKVLVV GNPANTNAYI AMKSAPDLPK KNFTAMLRLD HNRALSQLAA KSGKPVASIE 

       190        200        210        220        230        240 
KLAVWGNHSP TMYPDFRFAT AEGESLLKLI NDDVWNRDTF IPTVGKRGAA IIEARGLSSA 

       250        260        270        280        290        300 
ASAANAAIDH VRDWVLGTNG KWVTMGIPSD GSYGIPEDII YGVPVVCENG EYKRVEGLEI 

       310        320 
DAFSREKMDG TLAELLEERD GVAHLLKN

« Hide

References

[1]"Complete sequence of chromosome 2 of Burkholderia ambifaria MC40-6."
Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Lang D., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A. expand/collapse author list , Ramette A., Konstantinidis K., Tiedje J., Richardson P.
Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001026 Genomic DNA. Translation: ACB66292.1.
RefSeqYP_001810508.1. NC_010552.1.

3D structure databases

ProteinModelPortalB1Z1L1.
SMRB1Z1L1. Positions 3-325.
ModBaseSearch...

Protein-protein interaction databases

STRINGB1Z1L1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID6179650.
GenomeReviewsGene locus BamMC406_3825 in contig CP001026_GR.
KEGGbac:BamMC406_3825.
PATRIC19037312. VBIBurAmb82852_3947.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG289884.
OMADPNVAFK.
ProtClustDBPRK05442.

Family and domain databases

HAMAPMF_01517. Malate_dehydrog_2.
[Tree]
InterProIPR001557. L-lactate/malate_DH.
IPR022383. Lactate/malate_DH_C.
IPR001236. Lactate/malate_DH_N.
IPR015955. Lactate_DH/Glyco_Ohase_4_C.
IPR010945. Malate_DH_type2.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:3.90.110.10. lact_mal_DH. 1 hit.
G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KOK00024.
PANTHERPTHR23382. MDH_SF1. 1 hit.
PfamPF02866. Ldh_1_C. 1 hit.
PF00056. Ldh_1_N. 1 hit.
[Graphical view]
PIRSFPIRSF000102. Lac_mal_DH. 1 hit.
SUPFAMSSF56327. Lactate_DH/Glyco_hydro_4_C. 1 hit.
TIGRFAMsTIGR01759. MalateDH-SF1. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB1Z1L1_BURA4
AccessionPrimary (citable) accession number: B1Z1L1
Entry history
Integrated into UniProtKB/TrEMBL: May 20, 2008
Last sequence update: May 20, 2008
Last modified: December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info